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"Taming The Beast": Exploring The Lived Experience Of Relapsing Remitting Multiple Sclerosis Using A Life History Approach, Therese Burke Jan 2019

"Taming The Beast": Exploring The Lived Experience Of Relapsing Remitting Multiple Sclerosis Using A Life History Approach, Therese Burke

Theses

Multiple Sclerosis (MS) is a complex neurological disease affecting the central nervous system and is driven by a complex autoimmune cascade. The peak age of onset is between the ages of 20 and 40 years and shows a female preponderance of 3:1. The most common form of the disease affecting 85% of people living with the illness is called relapsing remitting MS (RRMS), and is characterised by unpredictable relapses or exacerbations which usually last a few weeks before returning to baseline function. There is the possibility of disease progression and non-reversible disability after many years. RRMS is also characterised by …


The Validity And Reliability Of The Basketball Jump Shooting Accuracy Test, Brenton Boddington Jan 2019

The Validity And Reliability Of The Basketball Jump Shooting Accuracy Test, Brenton Boddington

Theses

Valid and reliable jump shooting assessments that replicate in-game shooting performance are currently lacking in basketball. The aims of this thesis were to (1) describe the development of the newly-established Basketball Jump Shooting Accuracy Test (BJSAT), (2) determine the intra- and inter-rater reliability of the BJSAT, and (3) determine the content validity, construct validity, and test-retest reliability of the BJSAT. Basketball athletes from different playing levels (State Basketball League [SBL], n = 30, age: 22.7 ± 6.1 yr; SBL Division I, n = 11, age: 20.6 ± 2.1 yr) completed four trials of the BJSAT with each trial consisting of …


Evaluation Of The Impact Of A Low Dose Subcutaneous Lignocaine And Ketamine Infusion Utilising Nerve Excitability Studies In A Chronic Migraine Population., Christopher Rofe Jan 2019

Evaluation Of The Impact Of A Low Dose Subcutaneous Lignocaine And Ketamine Infusion Utilising Nerve Excitability Studies In A Chronic Migraine Population., Christopher Rofe

Theses

Migraine is a common condition in which the diagnosis is based on clinical grounds. There is no clinically available biophysical marker that can evaluate migraine. Migraines are linked to functional brain changes in the absence of structural abnormalities. A clinically useful tool capable of evaluating functional changes in patients with migraine could be used to aid diagnosis and management.

Patients with chronic migraine have frequent or continuous headache which is accompanied by significant morbidity. There are limited data available regarding treatment options for curtailment of chronic migraine. In this prospective observational study, patients suffering from chronic migraine underwent a prolonged …