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The Effectiveness And Clinical Outcomes Of The Minerva Cervical Thoracicjacket In Patients With Type Ii Odontoid Fractures, Sai̇t Öztürk, Fati̇h Serhat Erol, Beki̇r Akgün, Meti̇n Kaplan
The Effectiveness And Clinical Outcomes Of The Minerva Cervical Thoracicjacket In Patients With Type Ii Odontoid Fractures, Sai̇t Öztürk, Fati̇h Serhat Erol, Beki̇r Akgün, Meti̇n Kaplan
Turkish Journal of Medical Sciences
Background/aim: The objective of this study was to carry out a detailed analysis and assess the outcomes for the Minerva cervical thoracic jacket (CTJ) in patients with type II odontoid fractures who could not be surgically treated. Materials and methods: Twenty-six patients for whom the Minerva CTJ was used rather than surgery for different reasons were included in the study. All patients were fitted with the Minerva CTJ within the first 24 h following diagnosis. The patients were followed 4 weeks after hospital discharge and then at 2-week intervals. Results were considered significant at P < 0.05 and a 95% confidence interval was calculated. Results: Of the 26 patients, 17 were male and 9 were female. The mean age was 49.03 years old (range: 16?86 years old). Fusion occurred in 25 of the 26 patients (P = 0.004), and the mean time to fusion was 6.8 weeks (P = 0.002). The mean length of hospital stay was 4 days and the mean follow-up period was 7.3 weeks. None of the patients had any complications due to the Minerva CTJ and the mortality rate was 0%. Conclusions: The Minerva CTJ application was a safe and cheap technique in the management of type II odontoid fractures. It had a high fusion rate and no complications.
The Knowledge And High Seroprevalence Of Hepatitis A In A High-Risk Group(Agricultural Reproductive-Aged Women) In The Southeastern Region Of Turkey, Nebi̇ye Yentür Doni̇, Zeynep Şi̇mşek, Gülcan Gürses, Fadi̇le Yildiz Zeyrek, Muhsi̇n Akbaba
The Knowledge And High Seroprevalence Of Hepatitis A In A High-Risk Group(Agricultural Reproductive-Aged Women) In The Southeastern Region Of Turkey, Nebi̇ye Yentür Doni̇, Zeynep Şi̇mşek, Gülcan Gürses, Fadi̇le Yildiz Zeyrek, Muhsi̇n Akbaba
Turkish Journal of Medical Sciences
Background/aim: The aim of this study was to determine the seroprevalence of antihepatitis A virus (HAV), risk factors, and the knowledge of female farm workers living in the Southeastern Anatolia Region (SAR) of Turkey. Materials and methods: This representative cross-sectional survey was conducted between January and April of 2013 in the SAR. A total of 705 reproductive-aged women were randomly selected by clustering method using Epi Info software. The sera were analyzed for anti-HAV antibodies using ELISA. Sociodemographic information and the knowledge of female farm workers regarding hepatitis A were collected using a questionnaire. Results: Of the female farm workers, …
Endovascular Embolization In The Management Of Traumatic Andpostoperative Abdominopelvic Bleeding: A Single-Center Experience, Di̇lek Sağlam, Hasan Di̇nç, Abdulkadi̇r Gündüz, Ayşegül Cansu, Mehmet Hali̇l Öztürk
Endovascular Embolization In The Management Of Traumatic Andpostoperative Abdominopelvic Bleeding: A Single-Center Experience, Di̇lek Sağlam, Hasan Di̇nç, Abdulkadi̇r Gündüz, Ayşegül Cansu, Mehmet Hali̇l Öztürk
Turkish Journal of Medical Sciences
Background/aim: Endovascular embolization is widely used instead of surgery in the treatment of traumatic and postoperative abdominopelvic bleeding. The objective of this study is to evaluate the efficiency of computed tomography in the determination of active bleeding and the efficiency of endovascular embolization in traumatic and postoperative abdominopelvic bleeding. Materials and methods: Thirty-one patients admitted to our hospital with traumatic and postoperative abdominopelvic bleeding between January 2006 and September 2012 and treated with endovascular embolization were retrospectively enrolled in the study. In 15 hemodynamically stable patients, abdominal computed tomography was performed to detect the presence and/or localization of the hemorrhage. …
A Nationwide Evaluation Of Off-Label Drug Utilization In Turkey, Emi̇ne Nur Özdamar, Ahmet Akici, Ali̇ Alkan, Banu Bayar, Hakki Gürsöz
A Nationwide Evaluation Of Off-Label Drug Utilization In Turkey, Emi̇ne Nur Özdamar, Ahmet Akici, Ali̇ Alkan, Banu Bayar, Hakki Gürsöz
Turkish Journal of Medical Sciences
Background/aim: Off-label drug use (OLDU) is under the control of the Turkish Medicines and Medical Devices Agency (TMMDA) in Turkey. It was aimed to investigate demographic and medical features of patients with OLDU applications in Turkey. Materials and methods: A total of 4426 electronic OLDU application records of the TMMDA were evaluated retrospectively. Information regarding patients? demographic characteristics, diagnoses, requested drugs, institutions, and specialties of the physicians were evaluated. Results: OLDU applications were mostly made by rheumatologists (21.5%) and 95.2% of them were approved by the TMMDA. The mean age of the patients was 35 years and 54.4% of them …
Prevention Of Propofol Injection-Related Pain Using Pretreatment Transcutaneous Electrical Acupoint Stimulation, Luping Huang, Yuanyuan Pan, Sijia Chen, Minyuan Zhang, Xiuxiu Zhuang, Shenhui Jin, Junlu Wang, Qinxue Dai, Yunchang Mo
Prevention Of Propofol Injection-Related Pain Using Pretreatment Transcutaneous Electrical Acupoint Stimulation, Luping Huang, Yuanyuan Pan, Sijia Chen, Minyuan Zhang, Xiuxiu Zhuang, Shenhui Jin, Junlu Wang, Qinxue Dai, Yunchang Mo
Turkish Journal of Medical Sciences
Background/aim: This study aimed to study the effect of pretreatment transcutaneous electrical acupoint stimulation (TEAS) in preventing propofol injection-related pain. Materials and methods: A total of 360 patients who were to undergo elective hysteroscopy surgery were randomly divided into the following three groups of 120 patients each: control (Group C), sham TEAS (Group F), and TEAS (Group T). Patients in Group C did not undergo any treatment before surgery; 30 min before the induction of anesthesia, patients in Groups F and T underwent electrical stimulation of the bilateral LI4-PC6 acupoint. Patients in Group F were subjected to 'feeling flow', while …
Comparison Of Microscopy, Elisa, And Real-Time Pcr For Detectionof Giardia Intestinalis In Human Stool Specimens, Yunus Emre Beyhan, Zeynep Taş Cengi̇z
Comparison Of Microscopy, Elisa, And Real-Time Pcr For Detectionof Giardia Intestinalis In Human Stool Specimens, Yunus Emre Beyhan, Zeynep Taş Cengi̇z
Turkish Journal of Medical Sciences
Background/aim: This study included patients who had digestive system complaints between August 2015 and October 2015. The research was designed to compare conventional microscopy with an antigen detection ELISA kit and the TaqMan-based real-time PCR (RT-PCR) technique for detection of Giardia intestinalis in human stool specimens. Materials and methods: Samples were concentrated by formalin-ether sedimentation technique and microscopic examinations were carried out on wet mount slides. A commercially available ELISA kit (Giardia CELISA, Cellabs, Brookvale, Australia) was used for immunoassay. DNA was extracted from fecal samples of about 200 mg using the QIAamp Fast DNA Stool Mini Kit (QIAGEN, Hilden, …
Common Spink-1 Genetic Mutations Do Not Predispose To Crohn`S Disease, Nevi̇n Oruç, Necla Osmanoğlu, Çağdaş Aktan, Afi̇g Berdeli̇, Ahmet Ömer Özütemi̇z
Common Spink-1 Genetic Mutations Do Not Predispose To Crohn`S Disease, Nevi̇n Oruç, Necla Osmanoğlu, Çağdaş Aktan, Afi̇g Berdeli̇, Ahmet Ömer Özütemi̇z
Turkish Journal of Medical Sciences
No abstract provided.
Effect Of Varying Levels Of Concentrate On Growth Performance And Feed Economics In Nili-Ravi Buffalo Heifer Calves, Zeeshan Muhammad Iqbal, Muhammad Abdullah, Khalid Javed, Makhdoom Abdul Jabbar, Nisar Ahmad, Yasir Allah Ditta, Hamid Mustafa, Faisal Shahzad
Effect Of Varying Levels Of Concentrate On Growth Performance And Feed Economics In Nili-Ravi Buffalo Heifer Calves, Zeeshan Muhammad Iqbal, Muhammad Abdullah, Khalid Javed, Makhdoom Abdul Jabbar, Nisar Ahmad, Yasir Allah Ditta, Hamid Mustafa, Faisal Shahzad
Turkish Journal of Veterinary & Animal Sciences
An experiment was conducted to optimize the effect of concentrate levels on growth performance in Nili-Ravi buffalo heifers. These animals (n = 30), aged 4-6 months, were divided into three treatment groups (A, B, C) and were offered concentrate at the rate of 0.5%, 1.0%, and 1.5% of body weight for an 8-month period, respectively. The statistical data showed a significant (P < 0.01) effect on dry matter intake among all treatment groups. However, dietary treatments showed a nonsignificant effect on body weight gain. Treatment A showed a better (P < 0.01) feed conversion ratio (10.01 - 0.55) compared to treatment B (11.75 - 0.79) and C (12.85 - 0.74). The average body condition score, body measurements, and blood profiles were not affected by varying levels of concentrate. However, total serum protein was found lower (P < 0.01) in treatment A compared with the other two treatment groups. The cost for production per kg gain was 80.8% higher in treatment C and 46.6% higher in treatment B compared to treatment A. It can be concluded that buffalo heifers can be reared cost-effectively on a minimum concentrate level (0.5% of body weight) along with ad libitum green fodder.
The Csnp Scanning And Expression Analysis Of The Duck Fth1 Gene, Yu Zhang, Yiyu Tong, Yang Chen, Zhengyang Huang, Zhen Zhu, Yang Zhang, Qi Xu, Guohong Chen
The Csnp Scanning And Expression Analysis Of The Duck Fth1 Gene, Yu Zhang, Yiyu Tong, Yang Chen, Zhengyang Huang, Zhen Zhu, Yang Zhang, Qi Xu, Guohong Chen
Turkish Journal of Veterinary & Animal Sciences
Ferritin, heavy polypeptide 1 (FTH1) is a kind of ferritin complex that catalyzes the conversion of Fe(II) into Fe(III) to protect the cell from oxidative damage. Recent research has shown that FTH1 is also associated with several disease-related processes, such as inflammation and tumor progression and so on. In this study, the coding sequence (CDS) of FTH1 in Jinding ducks was cloned. The CDS sequence revealed an open reading frame of 546 nucleotides encoding a protein with 181 amino acids. Based on this sequence, the duck FTH1 protein is predicted to have conserved domains typical of eukaryotic ferritin. Only one …
Serotypes Of Salmonella Isolated From Feces Of Cattle, Buffalo,And Camel And Sensitivities To Antibiotics In Turkey, Hasan Hüseyi̇n Hadi̇mli̇, Yasemi̇n Pinarkara, Asli Sakmanoğlu, Zafer Sayin, Osman Ergani̇ş, Ali̇ Uslu, Huda Jihad Al-Shattrawi
Serotypes Of Salmonella Isolated From Feces Of Cattle, Buffalo,And Camel And Sensitivities To Antibiotics In Turkey, Hasan Hüseyi̇n Hadi̇mli̇, Yasemi̇n Pinarkara, Asli Sakmanoğlu, Zafer Sayin, Osman Ergani̇ş, Ali̇ Uslu, Huda Jihad Al-Shattrawi
Turkish Journal of Veterinary & Animal Sciences
In this study, Salmonella strains from dairy cows, calves with diarrhea, and buffalo and camel feces were isolated and serotyped. There were 869 feces samples (437 calves, 287 dairy cows, 100 buffalo, and 45 camels) collected from 13 provinces and 21 farms. Preenrichment feces samples were added to Rappaport-Vassiliadis medium. Samples were then subcultured on xylose lysine tergitol-4 agar and plates. Suspected colonies of Salmonella were confirmed by latex agglutination test. The isolates of Salmonella spp. were serotyped at the Etlik Central Veterinary Control Institute. In total, 40 Salmonella spp. were isolated, including 33 from calves, 5 from dairy cows, …
Aggressive Osteoblastoma Of The Cervical Vertebrae In A Turkish Angora Cat, Hyun Kim, Youngsu Lee, Kihoon Kim, Jiyong Kim, Saejong Yoo, A-Jin Lee, Hwi Yool Kim, Dai Jung Chung
Aggressive Osteoblastoma Of The Cervical Vertebrae In A Turkish Angora Cat, Hyun Kim, Youngsu Lee, Kihoon Kim, Jiyong Kim, Saejong Yoo, A-Jin Lee, Hwi Yool Kim, Dai Jung Chung
Turkish Journal of Veterinary & Animal Sciences
Aggressive osteoblastoma is a type of bone tumor rarely reported in veterinary literature. Osteoblastoma may be misdiagnosed as an osteosarcoma, which is a well-understood malignant bone tumor. Owing to poor prognosis, animals diagnosed with osteosarcoma are not always treated. In the present case, we diagnosed the tumor as aggressive osteoblastoma on the basis of macroscopic, microscopic, radiographic, and immunohistologic findings. The patient was treated via resections of the osteoblastoma and lived without metastasis for 3 years. This is the first reported case of aggressive feline osteoblastoma of the cervical vertebrae and will be useful for diagnosing and managing aggressive osteoblastoma.
Effects Of Season On Semen Parameters And Relationships Between Selected Semen Characteristics In Hypor Boars, Krzysztof Górski, Stanislaw Kondracki, Anna Wysokinska
Effects Of Season On Semen Parameters And Relationships Between Selected Semen Characteristics In Hypor Boars, Krzysztof Górski, Stanislaw Kondracki, Anna Wysokinska
Turkish Journal of Veterinary & Animal Sciences
The aim of this study was to evaluate the effect of the season of the year on the quality of Hypor boar semen and to determine the correlations between selected semen characteristics in particular seasons. Ejaculates from Hypor boars were analyzed for volume, sperm concentration, percentage of spermatozoa with normal motility, total number of spermatozoa, and the number of insemination doses per ejaculate. Microscopic slides were prepared from semen samples. Each sample was evaluated for the morphology of spermatozoa. Spermatozoa with normal morphology were counted, as well as those with both major and minor abnormalities. Spermatozoa were measured for morphometric …
The Effect Of Combining Vitamin E And C On The Viability Improvement Of Transfected Ovine Spermatogonial Stem Cells After Cryopreservation And Thawing, Hosein Shabani, Mohammad Zandi, Hamideh Ofogi, Mohammad Reza Sanjabi, Khosro Hoseini Pajooh
The Effect Of Combining Vitamin E And C On The Viability Improvement Of Transfected Ovine Spermatogonial Stem Cells After Cryopreservation And Thawing, Hosein Shabani, Mohammad Zandi, Hamideh Ofogi, Mohammad Reza Sanjabi, Khosro Hoseini Pajooh
Turkish Journal of Veterinary & Animal Sciences
The present study aimed to identify whether vitamin E and C and their combination in basal freezing medium improved the viability of postthaw transfected spermatogonial stem cells (SSCs). For this purpose, SSCs were harvested by enzymatic digestion twice. After enrichment and culture on Sertoli cell feeder layer, SSCs were characterized by using alkaline phosphatase staining and expression of oct-4 and c-kit genes as specific stem cell markers. As to the transfection of SSCs, different concentrations of DNA (0.2, 0.4, and 0.8 μg) and turbofect (0.4 and 0.8 μL) in 100 μL of medium were studied. The results showed that cryopreservation …
Molecular Types And Antimicrobial Resistance Profile Of Staphylococcus Aureus Isolated From Dairy Cows And Farm Environments, Dattatray Gandhale, Rahul Kolhe, Saba Nalband, Padmakar Deshpande, Urmila Jagtap, Chandrakant Dhandore, Sujata Bhave, Sameer Jadhav, Dushyant Muglikar, Smita Kolhe
Molecular Types And Antimicrobial Resistance Profile Of Staphylococcus Aureus Isolated From Dairy Cows And Farm Environments, Dattatray Gandhale, Rahul Kolhe, Saba Nalband, Padmakar Deshpande, Urmila Jagtap, Chandrakant Dhandore, Sujata Bhave, Sameer Jadhav, Dushyant Muglikar, Smita Kolhe
Turkish Journal of Veterinary & Animal Sciences
The aim of this study was to assess the prevalence of Staphylococcus aureus in cows with subclinical mastitis and detect enterotoxin genes and patterns of antimicrobial resistance. Out of 180 animals, subclinical mastitis was detected in 78 cows (46.99%) and three buffalo (21.43%). The prevalence of clinical mastitis was low (3.61%). S. aureus could be isolated from mastitic milk (67/81), udder swabs (38/81), floor swabs (13/27), milking machine liner (5/8), and healthy animals- milk (12/22). All the strains were confirmed by PCR targeting amplification of the femA gene. Out of 52 PCR-confirmed S. aureus samples, 17 were enterotoxin-producing strains. The …
Intravitreal Prn Ranibizumab Treatment For Macular Edemadue To Branch Retinal Vein Occlusion, Hasan Basri̇ Çakmak, Mücella Arikan Yorgun, Yasi̇n Toklu, Melek Mutlu
Intravitreal Prn Ranibizumab Treatment For Macular Edemadue To Branch Retinal Vein Occlusion, Hasan Basri̇ Çakmak, Mücella Arikan Yorgun, Yasi̇n Toklu, Melek Mutlu
Turkish Journal of Medical Sciences
Background/aim: To evaluate the effect of intravitreal pro re nata (PRN) ranibizumab treatment from the start on the best-corrected visual acuity (BCVA) and the central retinal thickness (CRT) in macular edema (ME) due to branch retinal vein occlusion (BRVO). Materials and methods: Patients with ME secondary to BRVO, who were treated on a PRN basis after a single intravitreal ranibizumab injection, were retrospectively evaluated. The main outcome measures were changes in BCVA and CRT as measured by optical coherence tomography. Results: The number of injections over 6 months was 2.43 ± 1.16. The mean BCVA of the patients was 0.84 …
Groin And Thigh Reconstructions With Pedicled Rectus Abdominis Myocutaneous Flaps, Hakan Uzun, Ozan Bi̇ti̇k, Yahya Baltu, Mehmet Dadaci, Aycan Uğur Kayikçioğlu
Groin And Thigh Reconstructions With Pedicled Rectus Abdominis Myocutaneous Flaps, Hakan Uzun, Ozan Bi̇ti̇k, Yahya Baltu, Mehmet Dadaci, Aycan Uğur Kayikçioğlu
Turkish Journal of Medical Sciences
Background/aim: Resection of tumors from the groin and thigh regions with safe margins often results in significant soft tissue defects, which preclude primary closure. This study presents a series of rectus abdominis myocutaneous flaps for irradiated thigh and groin wounds with the purpose of evaluating the efficacy and outcomes of these flaps in this population. Materials and methods: From 2008 to 2015, all patients who underwent resection of thigh or groin region tumors and reconstruction with an inferiorly based rectus abdominis myocutaneous flap were retrospectively identified. Medical records of the patients were reviewed. Results: A total of 27 patients, aged …
Effects Of A Closed System Suction Connector On Airwayresistance In Ventilated Neonates, Sezi̇n Ünal, Nuri̇ye Ebru Ergenekon, Ebru Kazanci, Selma Aktaş, Feri̇t Kulali, İbrahi̇m Murat Hirfanoğlu, Canan Türkyilmaz, Yildiz Atalay
Effects Of A Closed System Suction Connector On Airwayresistance In Ventilated Neonates, Sezi̇n Ünal, Nuri̇ye Ebru Ergenekon, Ebru Kazanci, Selma Aktaş, Feri̇t Kulali, İbrahi̇m Murat Hirfanoğlu, Canan Türkyilmaz, Yildiz Atalay
Turkish Journal of Medical Sciences
Background/aim: Increased airway resistance reduces the effectiveness of ventilation treatment. Endotracheal tubes (ETTs) and connectors contribute to resistance. However, the effect of a closed system suction (CSS) connector is not well known. We compared the in vivo resistance occurring with a CSS connector with that of the standard connector. Materials and methods: This prospective study was conducted at Gazi University Hospital's neonatal intensive care unit. Intubated neonates were studied for two cycles; each cycle contained two periods of ETT + connector pairs (15 min/period) as follows: cycle 1 [A: long ETT + standard connector; B: long ETT + CSS connector] …
Is There Any Difference In Tetanus Igg Levels Of Diabetic Patientswith Respect To The Presence Of Foot Ulcers?, Fati̇h Teki̇n, Mehmet Sürmeli̇, Zeynep Çi̇zmeci̇, Özlem Teki̇n, Ergi̇n Işik, Ömer Faruk Taner, Derun Taner Ertuğrul
Is There Any Difference In Tetanus Igg Levels Of Diabetic Patientswith Respect To The Presence Of Foot Ulcers?, Fati̇h Teki̇n, Mehmet Sürmeli̇, Zeynep Çi̇zmeci̇, Özlem Teki̇n, Ergi̇n Işik, Ömer Faruk Taner, Derun Taner Ertuğrul
Turkish Journal of Medical Sciences
Background/aim: The aim of this study was to reveal the tetanus immunization status of diabetic patients and to determine whether diabetic patients with foot ulcers have different TIG levels. Materials and methods: A cross-sectional study was designed that included diabetic patients with foot ulcers (n = 30) and diabetic patients without ulcers (n = 30). The groups were compared for serum TIG levels along with total serum protein, albumin, C-reactive protein (CRP), and total immunoglobulin G (Ig G). Results: For diabetic patients without foot ulcers, 17 of 30 (56.6%) patients were found to have nonprotective TIG levels whereas for diabetic …
Sex-Related Differences In Copd Assessment Test Scores Of Copd Populationswith Or Without Significant Anxiety And/Or Depression, Yelda Varol, Ceyda Anar, Pinar Çi̇men, Mehmet Ünlü, Hüseyi̇n Hali̇lçolar, Sali̇h Zeki̇ Güçlü
Sex-Related Differences In Copd Assessment Test Scores Of Copd Populationswith Or Without Significant Anxiety And/Or Depression, Yelda Varol, Ceyda Anar, Pinar Çi̇men, Mehmet Ünlü, Hüseyi̇n Hali̇lçolar, Sali̇h Zeki̇ Güçlü
Turkish Journal of Medical Sciences
Background/aim: Sex-related differences have not been thoroughly explored in chronic obstructive pulmonary disease (COPD). We aimed to evaluate possible sex-related differences in COPD Assessment Test (CAT) scores of COPD patients with or without significant anxiety and/or depression. Materials and methods: Stable COPD patients were prospectively enrolled in the study between July 2013 and April 2014. Levels of anxiety, depression, dyspnea, and health-related quality of life parameters were assessed using specific questionnaires, including the CAT and others. Demographic and clinical data were recorded and physiological tests were performed. All the data were compared to determine any sex-related differences. Results: A total …
Fecal Carriage Of Extended-Spectrum Beta-Lactamase-Producing Escherichia Coli And Klebsiella Spp. In A Turkish Community, Derya Çakir Erdoğan, Füsun Cömert, Eli̇f Aktaş Sepetci̇, Fürüzan Köktürk, Canan Külah
Fecal Carriage Of Extended-Spectrum Beta-Lactamase-Producing Escherichia Coli And Klebsiella Spp. In A Turkish Community, Derya Çakir Erdoğan, Füsun Cömert, Eli̇f Aktaş Sepetci̇, Fürüzan Köktürk, Canan Külah
Turkish Journal of Medical Sciences
Background/aim: The aim of this study was to determine the prevalence of fecal carriage of extended-spectrum beta-lactamase (ESBL)-producing bacteria, enzyme types, and risk factors affecting colonization. Materials and methods: A total of 576 stool samples from outpatients were examined between October 2012 and May 2013. Screening was done with selective EMB plates. ESBL were detected by double-disk synergy and confirmed agar strip gradient methods. Enzyme types were determined by PCR. Results: The prevalence of fecal carriage was found as 30% (173 of 576). Recent use of antibiotics, hospitalization and surgical operation, diabetes, crowded household populations, and old age were associated …
Significant Association Between Scgb1d4 Gene Polymorphisms And Susceptibility To Adenoid Hypertrophy In A Pediatric Population, Tali̇h Özdaş, Si̇bel Özdaş, Mehmet Ali̇ Babademez, Sami̇ Engi̇n Muz, Mahmut Huntürk Ati̇lla, Si̇bel Başti̇mur, Afi̇fe İzbirak, Kenan Kurt, Işilay Öz
Significant Association Between Scgb1d4 Gene Polymorphisms And Susceptibility To Adenoid Hypertrophy In A Pediatric Population, Tali̇h Özdaş, Si̇bel Özdaş, Mehmet Ali̇ Babademez, Sami̇ Engi̇n Muz, Mahmut Huntürk Ati̇lla, Si̇bel Başti̇mur, Afi̇fe İzbirak, Kenan Kurt, Işilay Öz
Turkish Journal of Medical Sciences
Background/aim: Adenoid hypertrophy (AH) is chronic enlargement of the adenoid tissue. The pathophysiology of the disease is unclear. We analyzed SCGB1D4 gene polymorphisms in order to determine the effect of the variants or their genetic combinations on AH. Materials and methods: We genotyped the SCGB1D4 (IIS) gene in 167 participants (95 children with AH and 72 controls) by performing DNA sequencing in blood samples. Results: We genotyped three single nucleotide polymorphisms (SNPs). In the analysis, we found that in the presence of those SNPs and the minor alleles of individual SNPs four haplotypes were associated with an increased risk of …
Attitudes And Behaviors Of Physicians In Dealing With Difficult Patientsand Relatives: A Cross-Sectional Study In Two Training And Research Hospitals, Kamuran Bahar Sandikci, Yusuf Üstü, Mert Muhi̇tti̇n Sandikci, Burcu Kayhan Teti̇k, Derya Işik, Mehmet Uğurlu
Attitudes And Behaviors Of Physicians In Dealing With Difficult Patientsand Relatives: A Cross-Sectional Study In Two Training And Research Hospitals, Kamuran Bahar Sandikci, Yusuf Üstü, Mert Muhi̇tti̇n Sandikci, Burcu Kayhan Teti̇k, Derya Işik, Mehmet Uğurlu
Turkish Journal of Medical Sciences
Background/aim: The aim of this study was to examine the reasons constituting the definition of 'difficult patient' and to evaluate attitudes and behaviors of physicians in coping with these patients and their relatives. Materials and methods: This cross-sectional study was conducted in May and June 2013 with 400 randomly selected physicians from different specialties working in two training and research hospitals in Ankara. A questionnaire was created by reviewing the relevant literature, by family medicine clinic, and delivered to the physicians following a pilot study. Results: In our study 92.8% of the physicians participating had experienced a negative contact with …
Radiation Therapy For Biliary Tract Tumors: The Joint Experience Of Three Centers, Mehmet Si̇nan Karabey, Eda Yi̇rmi̇beşoğlu Erkal, Ahmet Yolcu, Beki̇r Hakan Bakkal, Özlem Ay, Maksut Görkem Aksu, Emi̇ne Bi̇nnaz Sarper, Haldun Şükrü Erkal
Radiation Therapy For Biliary Tract Tumors: The Joint Experience Of Three Centers, Mehmet Si̇nan Karabey, Eda Yi̇rmi̇beşoğlu Erkal, Ahmet Yolcu, Beki̇r Hakan Bakkal, Özlem Ay, Maksut Görkem Aksu, Emi̇ne Bi̇nnaz Sarper, Haldun Şükrü Erkal
Turkish Journal of Medical Sciences
Background/aim: This study presents the joint experience of three centers in the treatment of patients with biliary tract tumors with radiation therapy (RT). Materials and methods: The records of 27 patients were retrospectively reviewed. All of the patients who had undergone surgical resection received postoperative adjuvant RT, whereas all of the patients who had not undergone a surgical resection received RT with palliative intent. Twenty patients with adequate performance status were treated with RT and chemotherapy, while the remaining seven patients were treated with RT alone. Results: Follow-up ranged from 1 to 44 months. Local control was not achieved in …
Wheezing, Asthma, And Atopy In Premature Infants At 2 Years Of Age, Sevi̇m Ünal, Ayşenur Kaya, Leyla Bi̇lgi̇n, Emi̇ne Di̇bek Misirlioğlu, Can Naci̇ Kocabaş
Wheezing, Asthma, And Atopy In Premature Infants At 2 Years Of Age, Sevi̇m Ünal, Ayşenur Kaya, Leyla Bi̇lgi̇n, Emi̇ne Di̇bek Misirlioğlu, Can Naci̇ Kocabaş
Turkish Journal of Medical Sciences
Background/aim: We aimed to evaluate wheezing, bronchial asthma (BA), and atopy in premature infants at 2 years of age via a crosssectional study. Materials and methods: Premature infants at <37 weeks of gestational age (GA) were assessed for atopy by skin-prick test and serum immunoglobulin E level at 2 years of age. The family's and infant's histories of allergy, BA, atopy, and wheezing were obtained by questionnaire and from hospital records. Results: There were 98 infants, with mean birth weight (BW) 1517.4 ± 486.5 g and GA 30.8 ± 2.9 weeks. The frequencies of wheezing, asthma, and bronchopulmonary dysplasia (BPD) were 32.7%, 16.3%, and 14.3%, respectively. Skin-prick tests were positive for 11 subjects, with allergy to cereals for 7 infants, egg for 3, and peanut for 1. Wheezing was related to GA, BW, respiratory distress syndrome, mechanical ventilation, sepsis, asphyxia, smoking, antenatal steroid, BA, palivizumab prophylaxis, number of people in the household, and duration of hospitalization (P < 0.05). Wheezing was negatively correlated to GA. Family history of BA, smoking, and number of people in the household were linked to BA (P < 0.05). Conclusion: Wheezing was related to degree of premature birth, but BA was linked to BA in the family and smoking. Increased gestation should improve the infant's respiratory health up to 2 years of age.
Predictive Values Of Plasma Kl-6 In Bronchopulmonary Dysplasia In Preterm Infants, Di̇lek Di̇lli̇, Ahmet Özyazici, Arzu Dursun, Serdar Beken, Nurdan Di̇nlen Fettah, Aysegul Zenci̇roğlu, Nurullah Okumuş
Predictive Values Of Plasma Kl-6 In Bronchopulmonary Dysplasia In Preterm Infants, Di̇lek Di̇lli̇, Ahmet Özyazici, Arzu Dursun, Serdar Beken, Nurdan Di̇nlen Fettah, Aysegul Zenci̇roğlu, Nurullah Okumuş
Turkish Journal of Medical Sciences
Background/aim: It has been suggested that plasma KL-6 increases in premature infants with bronchopulmonary dysplasia (BPD). We aimed to evaluate the predictive values of KL-6 in BPD. Materials and methods: The study was performed in preterm neonates with birthweight ≤1500 g and gestational age ≤32 weeks. Plasma KL-6 levels were measured on postnatal days 1, 7, and 14. Results: BPD was identified in eight of the 28 study infants. On postnatal days 1 and 7, plasma KL-6 levels were similar in infants with BPD [on day 1: 8.9 (7.5-17.8) U/mL and on day 7: 16.8 (10.5-47.7) U/mL] and without BPD …
Evaluation Of Quality Of Life And Cost-Effectiveness Of Definitive Surgery And The Levonorgestrel Intrauterine System As Treatment Options For Heavy Menstrual Bleeding, Cevdet Adigüzel, Sevtap Seyfetti̇noğlu, Deni̇z Aka Satar, Sefa Arlier, Eda Eski̇mez, Fatma Kaya, Hakan Nazi̇k
Evaluation Of Quality Of Life And Cost-Effectiveness Of Definitive Surgery And The Levonorgestrel Intrauterine System As Treatment Options For Heavy Menstrual Bleeding, Cevdet Adigüzel, Sevtap Seyfetti̇noğlu, Deni̇z Aka Satar, Sefa Arlier, Eda Eski̇mez, Fatma Kaya, Hakan Nazi̇k
Turkish Journal of Medical Sciences
Background/aim: This study aimed to compare the levonorgestrel intrauterine system (LNG-IUS) with abdominal hysterectomy (TAH) and total laparoscopic hysterectomy (TLH) as first-line treatments for heavy menstrual bleeding (HMB). Materials and methods: Ninety-eight patients aged 20-55 years who complained of regular heavy menstrual bleeding were enrolled in the study. The TAH group included 29 patients, the LNG-IUS group included 34, and the TLH group included 35. These groups were compared in terms of quality of life and the cost-effectiveness of the selected methods. Quality of life was assessed using the 36-Item Short Form (SF-36), and cost-effectiveness was assessed according to the …
Vitamin E As A Novel Therapy In The Treatment Of Acute Aluminum Phosphide Poisoning, Zahra Halvaei, Hiva Tehrani, Kambiz Soltaninejad, Mohammad Abdollahi, Shahin Shadnia
Vitamin E As A Novel Therapy In The Treatment Of Acute Aluminum Phosphide Poisoning, Zahra Halvaei, Hiva Tehrani, Kambiz Soltaninejad, Mohammad Abdollahi, Shahin Shadnia
Turkish Journal of Medical Sciences
Background/aim: Aluminum phosphide (AlP) is commonly used as a fumigant in developing countries. Induction of oxidative stress is one of the most important mechanisms of its toxicity. In this regard, and considering that there is no specific antidote for its treatment, the aim of this study was to evaluate the effect of vitamin E in the treatment of acute AlP poisoning. Materials and methods: This was a clinical trial on acute AlP poisoned patients. All patients received supportive treatment. In addition, the treatment group received vitamin E (400 mg/BD/IM). Level of malondialdehyde (MDA) and total antioxidant capacity of plasma were …
Analysis Of Epidemiology And Risk Factors For Mortality In Ventilator-Associated Pneumonia Attacks In Intensive Care Unit Patients, Ayşe But, Meltem Arzu Yetki̇n, Di̇lek Kanyilmaz, Hali̇de Aslaner, Ali̇ye Baştuğ, Adalet Aypak, Pinar Öngürü, Esragül Akinci, Nevzat Mehmet Mutlu, Hurrem Bodur
Analysis Of Epidemiology And Risk Factors For Mortality In Ventilator-Associated Pneumonia Attacks In Intensive Care Unit Patients, Ayşe But, Meltem Arzu Yetki̇n, Di̇lek Kanyilmaz, Hali̇de Aslaner, Ali̇ye Baştuğ, Adalet Aypak, Pinar Öngürü, Esragül Akinci, Nevzat Mehmet Mutlu, Hurrem Bodur
Turkish Journal of Medical Sciences
Background/aim: The aim of this study was to investigate the epidemiologic characteristics, the causative microorganisms and their antimicrobial susceptibility patterns, and the prognostic risk factors for mortality in critically ill patients with ventilator-associated pneumonia (VAP). Materials and methods: In this retrospective observational study, all the critically ill patients with VAP hospitalized in a medical/surgical intensive care unit (ICU) between January 2010 and June 2015 were evaluated. Patients' demographic features and microbiological data were reviewed. Results: A total of 417 patients were clinically diagnosed with VAP; 51.1% of them were male and the average age was found as 69.9 ± 15.9 …
The Effect Of Trimetazidine On Renal Oxidative Stress In Partialand Complete Ureteral Obstructions In A Rat Model, Sema Nur Ayyildiz, Ali̇ Ayyildiz, Erdal Benli̇, Selma Cirrik, Rüştü Cankon Germi̇yanoğlu, Tevfi̇k Noyan, Abdullah Çirakoğlu
The Effect Of Trimetazidine On Renal Oxidative Stress In Partialand Complete Ureteral Obstructions In A Rat Model, Sema Nur Ayyildiz, Ali̇ Ayyildiz, Erdal Benli̇, Selma Cirrik, Rüştü Cankon Germi̇yanoğlu, Tevfi̇k Noyan, Abdullah Çirakoğlu
Turkish Journal of Medical Sciences
Background/aim: Renal oxidative stress occurs in ureteral obstructions. The purpose of this study was to investigate the effect of the antioxidant and antiischemic agent trimetazidine (TMZ) on oxidative stress following ureteral obstruction. Materials and methods: Ten groups were established. Sham groups were checked as controls after 1 and 3 weeks. The other 8 groups had partial or complete ureteral obstruction while receiving or not receiving trimetazidine (TMZ) at 5 mg/kg daily and were evaluated after either 1 week or 3 weeks. Creatinine and cystatin C measurements were performed in the serum. Malondialdehyde, myeloperoxidase, catalase, and glutathione peroxidase activity were measured …
The Effects Of Iloprost And Alprostadil On Ischemia-Reperfusion Injury In Preventing Inflammation, Tissue Degeneration, And Apoptosis In Rat Skeletal Muscle, Eli̇f Güneysu, Atacan Emre Koçman, Orhan Özati̇k, Cengi̇z Ovali, Betül Can, İbrahi̇m Özkan Alataş, Mustafa Behçet Sevi̇n
The Effects Of Iloprost And Alprostadil On Ischemia-Reperfusion Injury In Preventing Inflammation, Tissue Degeneration, And Apoptosis In Rat Skeletal Muscle, Eli̇f Güneysu, Atacan Emre Koçman, Orhan Özati̇k, Cengi̇z Ovali, Betül Can, İbrahi̇m Özkan Alataş, Mustafa Behçet Sevi̇n
Turkish Journal of Medical Sciences
Background/aim: The protective effects of prostaglandin (PG) analogs on ischemia-reperfusion (I/R) have been well documented; however, comparative studies are lacking. The aim of the present study was to determine whether iloprost or alprostadil is more effective in preventing muscle I/R injury. Materials and methods: Thirty-two rats were divided into four groups (n = 8): sham, control, IL (I/R + iloprost), and AL (I/R + alprostadil). I/R was induced by a tourniquet in the hindlimb for 3 h/3 h. The IL and AL groups received iloprost (0.5 ng kg-1 min-1) and alprostadil (0.05 μg kg-1 min-1) during reperfusion, respectively. After 6 …