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Medicine and Health Sciences

SelectedWorks

Selected Works

2006

HIV

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Identifying Important Explanatory Variables For Time-Varying Outcomes., Oliver Bembom, Maya L. Petersen, Mark J. Van Der Laan Dec 2006

Identifying Important Explanatory Variables For Time-Varying Outcomes., Oliver Bembom, Maya L. Petersen, Mark J. Van Der Laan

Maya Petersen

This chapter describes a systematic and targeted approach for estimating the impact of each of a large number of baseline covariates on an outcome that is measured repeatedly over time. These variable importance estimates can be adjusted for a user-specified set of confounders and lend themselves in a straightforward way to obtaining confidence intervals and p-values. Hence, they can in particular be used to identify a subset of baseline covariates that are the most important explanatory variables for the time-varying outcome of interest. We illustrate the methodology in a data analysis aimed at finding mutations of the human immunodeficiency virus …


Predictors Of Quality Of Life In Hiv-Infected Rural Women: Psychometric Test Of The Chronic Illness Quality Of Life Ladder, C. Murdaugh, L. Moneyham, K. Jackson, Kenneth D. Phillips, A. Tavakoli Jan 2006

Predictors Of Quality Of Life In Hiv-Infected Rural Women: Psychometric Test Of The Chronic Illness Quality Of Life Ladder, C. Murdaugh, L. Moneyham, K. Jackson, Kenneth D. Phillips, A. Tavakoli

Kenneth D. Phillips

The Chronic Illness Quality of Life Ladder (CIQOLL) underwent psychometric testing in a sample of 278 women with HIV disease. The CIQOLL, a self-anchoring striving scale based on Cantril’s Ladder, measures seven domains (physical , emotional, financial, family and friends, spiritual well-being, peace of mind, and overall life satisfaction) across four time periods (present, past, future, life without a diagnosis of HIV). The domains were derived from focus groups with persons with HIV disease. Women with a diagnosis of HIV Infection, age 18 or older, residing in rural areas in the southeastern United States, completed questionnaires that measured physical functioning, …