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Induction Of Apoptosis In Human Prostate Cancer Cells By Resveratrol, Gary Zulfikar Morris Oct 2000

Induction Of Apoptosis In Human Prostate Cancer Cells By Resveratrol, Gary Zulfikar Morris

Chemistry & Biochemistry Theses & Dissertations

Recently attention has been brought to trans-resveratrol's {TR) anticancer activity, as determined through a number of cultured cancer cell models. This activity was attributed to TR behaving as an estrogen, and the orientation of TR' s hydroxyl groups. Based on this work it was of interest to determine whether TR would also be toxic in prostate cancer cells; if toxic, did TR induce necrosis or apoptosis in the cells; was it toxic through hormone mediated pathways; and were TR's hydroxyl groups responsible for its biological activity. To this end, cellular viability was assessed in two different prostate cancer cell …


Role Of Lipolysis And Lipogenesis In The Development Of Diet-Induced Obesity, Michael John Davies Jul 2000

Role Of Lipolysis And Lipogenesis In The Development Of Diet-Induced Obesity, Michael John Davies

Theses and Dissertations in Biomedical Sciences

Obesity is an increasingly common public health problem with approximately one-half of the American adult population overweight and one-quarter considered obese. This alarming trend has led researchers to determine potential causative factors of excess weight gain in humans. However, it is difficult to discern whether perturbations that result in obesity are the cause or simply the result of the obese state. Diet-induced obesity is one of the animal models that allow researchers to address temporal issues. Our laboratory utilizes a diet-induced obesity model in which Sprague-Dawley rats are placed on a purified moderately high fat diet and ultimately diverge into …


Medical Students And Their Attitudes Toward Abortion: An Assessment Of Which Factors Influence Medical Students' Willingness Or Unwillingness To Perform Abortions, Katherine M. Krupa Jul 2000

Medical Students And Their Attitudes Toward Abortion: An Assessment Of Which Factors Influence Medical Students' Willingness Or Unwillingness To Perform Abortions, Katherine M. Krupa

Sociology & Criminal Justice Theses & Dissertations

The purpose of this research is to determine which factors, if any, influence medical students' willingness or unwillingness to perform abortions. Ample research has been conducted evaluating both the general population's and college students' attitudes toward abortion; however, limited research has been collected on medical students. The present research study attempts to fill this void. The following research questions will be reviewed and evaluated throughout the current study: (1) What personal factors if any influence medical students' willingness or unwillingness to terminate a pregnancy; (2) Are medical students willing to perform abortions for the reasons that women are requesting them; …


The Pediatric Breathing Survey, Linda J. Galloway Apr 2000

The Pediatric Breathing Survey, Linda J. Galloway

Health Services Research Dissertations

To ensure culturally-sensitive assessments, the researcher designed a Pediatric Breathing Survey (PBS) to measure quality of life for African-American children. The purpose of this study was to test whether the PBS is a reliable and valid instrument. Comparisons of group differences on race, income and parent's level of education based on parent responses to the questionnaires were conducted. More specifically, differences in Health Related Quality of Life (HRQOL) between Caucasian and African-American children were examined. The researcher-designed instrument was compared to Juniper's Pediatric Asthma Quality of Life Questionnaire. The sample consisted of parents of 84 school-aged children diagnosed with asthma. …


Explanatory Power Of The Behavior Model Of Utilization For Pediatric Asthma Health Care In An Urban Managed Care Setting, Kathie Marie Sawyer Zimbro Apr 2000

Explanatory Power Of The Behavior Model Of Utilization For Pediatric Asthma Health Care In An Urban Managed Care Setting, Kathie Marie Sawyer Zimbro

Health Services Research Dissertations

The Behavior Model of Utilization played a key role in explaining health services use for pediatric members with asthma in one urban, regional managed care company. The critical role the asthma management program played in promoting the health and well-being of enrolled members was elucidated. Information gleaned from this empirical study can be used to encourage appropriate resource utilization, formulate pediatric asthma health policy, and deliver cost-effective, quality health care. More importantly, managed care company administrators and clinicians can demonstrate the value of their efforts by achieving measurable improvements in the health and well-being of children in the communities they …


Factors Associated With Asthma Readmissions In Children's Hospitals, Maria Acedo Kronenburg Jan 2000

Factors Associated With Asthma Readmissions In Children's Hospitals, Maria Acedo Kronenburg

Health Services Research Dissertations

Asthma is the most common chronic illness of childhood. Pediatric asthma hospitalization rates and costs of care have risen in recent years. Readmissions, an adverse outcome often used to monitor quality of care, may account for the increase in asthma hospitalization rates. This research examined selected hospital and patient risk factors related to asthma readmissions, using Donabedian's framework for structure, process, and outcomes to assess the quality of care for children with asthma. Outcome measures included readmission for asthma within one year of initial hospitalization, readmission within 30 days, and multiple readmissions within one year. Structure factors measured were insurance …


Perceptions Of Clinical Psychologists Relative To Other Mental Health Providers, Glenora Nelson Jan 2000

Perceptions Of Clinical Psychologists Relative To Other Mental Health Providers, Glenora Nelson

Psychology Theses & Dissertations

There is a myriad of job titles that exist within the mental health profession. Public perception about the differences between these professionals has been the focus of many studies and the results generally suggest that the public cannot clearly distinguish among these mental heath professionals. The present study is also concerned with perceptions about the various mental health professionals, in particular, perceptions of clinical psychologists relative to other professionals in this field. Undergraduate psychology students age 18–47 participated in a study of perceptions and attitudes about the qualifications and competence of clinical psychologists, professional counselors, psychiatrists and clinical social workers. …


Portuguese-Americans And Mental Health Treatment Client-Therapist Ethnic Match, Ethnic Identity, And Satisfaction With Treatment, Katherine B. Gamble Jan 2000

Portuguese-Americans And Mental Health Treatment Client-Therapist Ethnic Match, Ethnic Identity, And Satisfaction With Treatment, Katherine B. Gamble

Psychology Theses & Dissertations

Multicultural issues in psychotherapy have increasingly been recognized as important in the provision of mental health services to our diverse population. Issues such as beliefs about mental health, attitudes toward authority, and even world view affect how clients access and make use of psychotherapy. Cultural views are essential to how one sees the world, and consequently there is much debate about whether clients would benefit from having therapists from the same cultural background. Ethnic identity, or the degree to which a person holds to the beliefs of their culture of origin, consequently plays an important role in psychotherapy. The Portuguese …