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Articles 1 - 18 of 18
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The Relation Between Children‟S Socio-Economic Status And Their Performance On The Passive Subtest Of The Diagnostic Evaluation Of Language Variation – Norm Referenced, Maggie Faulk Deville
The Relation Between Children‟S Socio-Economic Status And Their Performance On The Passive Subtest Of The Diagnostic Evaluation Of Language Variation – Norm Referenced, Maggie Faulk Deville
Honors Theses
No abstract provided.
An Examination Of Errors Of Coherence In Adolescent Sentence Combining, Ginger Gunter Collins
An Examination Of Errors Of Coherence In Adolescent Sentence Combining, Ginger Gunter Collins
LSU Doctoral Dissertations
Young adolescents should be able to write organized multi-paragraph compositions that develop a central idea and unfold in logical and sequential order, unified through the use of transitional words and phrases. In other words, the compositions should not just consist of a string of related sentences, but represent a dynamic text that has coherence. It is important that speech-language pathologists develop quick and reliable methods for assessing coherence to aid in making data driven decisions and progress monitoring consistent with principles of Responsiveness to Intervention. Yet, the holistic quality of coherence makes it difficult to assess, both within a composition …
Identification Of Novel Core And Accessory Factors Involved In Nucleotide Excision Repair In Yeast, Danielle Marie Tatum
Identification Of Novel Core And Accessory Factors Involved In Nucleotide Excision Repair In Yeast, Danielle Marie Tatum
LSU Doctoral Dissertations
ABSTRACT Nucleotide excision repair (NER) is a highly conserved DNA repair mechanism which deals with a wide variety of bulky, helix-distorting lesions, such as UV-induced cyclobutane pyrimidine dimers (CPDs). NER is traditionally grouped into two pathways: global genomic repair (GGR), which is operative throughout the genome, and transcription coupled repair (TCR), which is dedicated to rapid repair of the transcribed strand of actively transcribed genes. Though most of the core NER proteins are known, the exact biochemical mechanism of eukaryotic NER remains elusive. This dissertation focused on identifying novel core and accessory factors which function in NER. In the budding …
Pharmacological And Non-Pharmacological Approaches To Prevent Hypertension-Induced Renal Disease In The Spontaneously Hypertensive Rate, Carrie Marie Elks
Pharmacological And Non-Pharmacological Approaches To Prevent Hypertension-Induced Renal Disease In The Spontaneously Hypertensive Rate, Carrie Marie Elks
LSU Doctoral Dissertations
Hypertension affects 50 million Americans and remains the second leading cause of renal failure in the United States. Current pharmacological and non-pharmacological approaches to treat hypertension have proven effective, but the complexities of the disease and its renal effects warrant the need for new treatments. The hypothesis of this dissertation was that pharmacological or non-pharmacological approaches to reducing inflammation and oxidative stress would prevent hypertension-induced renal injury in the spontaneously hypertensive rat (SHR). In the first study, we blocked the inflammatory transcription factor, nuclear factor-kappa B (NF-ĸB), with pyrrolidine dithiocarbamate in the SHR kidney. In treated SHR, blood pressure decreased, …
The Role Of Inflammatory Molecules In Hypertension, Jeffrey Paul Cardinale
The Role Of Inflammatory Molecules In Hypertension, Jeffrey Paul Cardinale
LSU Doctoral Dissertations
Hypertension is a serious condition with high morbidity and mortality rates, as well as a major predisposing factor for multiple cardiovascular and renal diseases. Angiotensin II (Ang II) of the renin-angiotensin system (RAS) plays a pivotal role in propagating the hypertensive response. Moreover, hypertension is considered a chronic low-grade inflammatory condition that intimately involves the actions of proinflammatory cytokines (PICs) such as tumor necrosis factor-alpha (TNF). Recent evidence highlights the role that inflammation, specifically TNF, plays in hypertension and in regulating the RAS, but the understanding as to how inflammation is regulated following Ang II or TNF activation, as well …
Time Of Day Effects On Language Discourse In Healthy Aging And Dementia, Amanda L. Stead
Time Of Day Effects On Language Discourse In Healthy Aging And Dementia, Amanda L. Stead
LSU Doctoral Dissertations
This study’s purpose was to investigate whether language discourse follows a diurnal pattern across one 10-hour day in normal healthy aging individuals (NHA) and individuals with mild to moderate Alzheimer’s disease. Ten healthy older adults; and ten older adults clinically labeled with probable Alzheimer’s disease were recruited for this study. Measurements of procedural language, narrative language, and cognition, the Benton Judgment of Line Orientation (BJLO), were collected across one day at 9:00am, 12:00pm, 3:00 pm, and 6:00pm. Language samples were evaluated for linguistic variables to evaluate the quantity and quality of the discourse samples. Results indicated that the two groups …
A Survey Of Selected Representations Of The Stroke And Aphasia Quality Of Life Scale-39 Items, Dara Lynn Elizabeth Deroche
A Survey Of Selected Representations Of The Stroke And Aphasia Quality Of Life Scale-39 Items, Dara Lynn Elizabeth Deroche
LSU Master's Theses
This research was designed to gain information that could be used in the future to improve quality of life measures for people with aphasia. Aphasia is a language disorder resulting from stroke or traumatic brain injury. People with aphasia exhibit difficulty producing and understanding verbal and written language. Existing quality of life measures, while valid and reliable for those with mild to moderate aphasia, are often unable to be used for those with severe aphasia. The written text is too complex for them to comprehend. Other studies have been done supporting the idea that pictures aid in the comprehension of …
Comparison Of The Diagnostic Evaluation Of Language Variation-Screening Test (Delv-St) To Two Other Screeners For Low-Income, African American Children, Christy Wynn Moland
Comparison Of The Diagnostic Evaluation Of Language Variation-Screening Test (Delv-St) To Two Other Screeners For Low-Income, African American Children, Christy Wynn Moland
LSU Doctoral Dissertations
The purpose of this study was to examine the validity of the DELV-ST by comparing it to two other screeners, the Fluharty-2 and the Washington-Craig Language Screener (WCLS). The participants were 73 African American Pre-K and Head Start children, aged four- to five-years-old. Fail rates were higher than what has been reported in the literature. They were highest for the Fluharty-2 (57%), lower for the DELV-ST (52%), and lowest for the WCLS (46%); however, there were no statistical differences in the fail rates by screener. Approximately 54% of the children passed or failed all screeners. Unfortunately, the remaining 46% failed …
Arginine Metabolism In The Edwardsiella Ictaluri- Channel Catfish Macrophage Dynamic, Wes Arend Baumgartner
Arginine Metabolism In The Edwardsiella Ictaluri- Channel Catfish Macrophage Dynamic, Wes Arend Baumgartner
LSU Doctoral Dissertations
Edwardsiella ictaluri encodes a urease operon and an arginine decarboxylase (AdiA) that are required for virulence in head kidney derived macrophages (HKDM). The urease produces ammonia in amounts sufficient to alter environmental pH from acid to neutral. A hypothetical model was proposed, involving arginine metabolism in E. ictaluri infected HKDM, focusing on bacterial urease, AdiA, a second arginine decarboxylase (SpeA), and agmatinase (SpeB). Using fluorescence based ratiometric pH determination of E. ictaluri in live HKDM, it was shown that E. ictaluri modulates HKDM phagosome pH to above six. Urease and AdiA mutants failed to up-regulate vacuole pH, while vacuole pH …
Characterization Of Spiroplasma Mirum And Its Role In Transmissible Spongiform Encephalopathies, Hilari Maree French
Characterization Of Spiroplasma Mirum And Its Role In Transmissible Spongiform Encephalopathies, Hilari Maree French
LSU Doctoral Dissertations
There are many contradictory reports in the literature involving the culture of Spiroplasma mirum, its resistance to disinfectants and antibiotics, and its potential role in Transmissible Spongiform Encephalopathies (TSEs). These contradictions led to an interest in a possible link between spiroplasma and TSEs and the development of a research plan to elucidate this connection. It was hypothesized that Spiroplasma was associated with a neurodegenerative disease such as TSE. In this work we further characterized S. mirum laboratory strains and continued to evaluate the possible correlations they have with TSE infections and the prion. To optimize recovery of S. mirum from …
Mapping And Modeling Of Neglected Tropical Diseases In Brazil And Bolivia, Paula Mischler
Mapping And Modeling Of Neglected Tropical Diseases In Brazil And Bolivia, Paula Mischler
LSU Doctoral Dissertations
Accurately defining disease distributions and calculating disease risk is an important step in the control and prevention of diseases. This study used geographical information systems and remote sensing technologies within the MaxEnt ecological niche modeling program to create predictive risk maps for leprosy and Schistosomiasis in Brazil and Chagas disease in both Brazil and Bolivia. New disease cases were compiled for leprosy, Schistosomiasis, and Chagas disease from the Brazilian ministry of Health for 2001 to 2009 and the data was stratified to a 10,000 population for each municipality. Bolivian Chagas prevalence rates were calculated from 2007 to 2009 survey data. …
The Tick Response To Rickettsial Dissemination During Typical And Atypical Rickettsial Infection, Piyanate Sunyakumthorn
The Tick Response To Rickettsial Dissemination During Typical And Atypical Rickettsial Infection, Piyanate Sunyakumthorn
LSU Doctoral Dissertations
Ticks are the only disease vectors for spotted fever group (SFG) Rickettsia which are obligate intracellular bacteria belonging to the genus Rickettsia. In nature, ticks maintain the infection of SFG Rickettsia via vertical and horizontal transmission. However, the prevalence of rickettsial transmission is limited to certain species of ticks, and this limitation is known as a specific tick/Rickettsia relationship. Due to the continuous increase of tick-borne rickettsial disease cases in the United States, which contrasts with very low prevalence of Rickettsia in tick vectors, the study of vector competence of tick to Rickettsia is needed in order to understand the …
Using The Ambulatory Phonation Monitor To Measure The Vocal Parameters Of Older People With And Without Parkinson's Disease, Danielle Marie Boudreaux
Using The Ambulatory Phonation Monitor To Measure The Vocal Parameters Of Older People With And Without Parkinson's Disease, Danielle Marie Boudreaux
LSU Master's Theses
Our project was designed to determine if there was a difference in vocal parameters, including mean fundamental frequency, mean amplitude, and total phonation time, between individuals diagnosed with Parkinson’s disease (PD) and age-and gender-matched individuals without a diagnosis of any neurologic or neurodegenerative diseases (NO PD) using the Ambulatory Phonation Monitor (APM: KayPENTAX, Lincoln Park, New Jersey). The APM was designed to gather objective data in a naturalistic environment by having participants wear the device over the course of three 8-hour days. The APM measured total phonation time, mean amplitude, and mean fundamental frequency throughout that time. The participants wore …
Arbovirus Phenotype Alters Transmission Potential, Rebecca C. Christofferson
Arbovirus Phenotype Alters Transmission Potential, Rebecca C. Christofferson
LSU Doctoral Dissertations
Extrinsic and environmental factors are known to affect the transmission of arthropod-borne viruses (arboviruses), including variations in the arthropod vector populations. Differences among these factors have been associated with differential transmission and are sometimes used to control the spread of an arbovirus through a vertebrate population in an effort to prevent or disrupt an outbreak. However, diversity in intrinsic viral populations, such as genetic and phenotypic variability, is not often accounted for when considering alterations in transmission. Presented in this dissertation are four experimental studies that explore the contribution of viral intrinsic factors, especially phenotypic variability, to the transmission potential …
Treatment Effects Of Attention Process Training For An Individual With Idiopathic Parkinson's Disease, Erin Renee' Guillory
Treatment Effects Of Attention Process Training For An Individual With Idiopathic Parkinson's Disease, Erin Renee' Guillory
LSU Master's Theses
Parkinson’s disease (PD) is characterized by a degeneration of the substantia nigra, resulting in a loss of dopaminergic neurons. Cognitive impairments, evident in 72% of people with PD (PWP) are indicated by deficits in visuospatial capacity, memory, executive functioning, and attention (Cooper, Sagar, Jordan, Harvey, & Sullivan, 1991; Duffy, 2005). Unfortunately, to date, there is little research that demonstrates improvement of these cognitive processes, particularly those affecting memory recall and attentional skills. The purpose of this study was to examine the effects of utilizing Attention Process Training (APT; Sohlberg & Mateer, 2005), a therapeutic protocol designed for individuals who have …
Biomechanical Evaluation Of Medial And Lateral Approaches For Experimentally Created Medial Condylar Fractures Of The Equine Third Metacarpal Bone, Saybl Beauton Sprinkle
Biomechanical Evaluation Of Medial And Lateral Approaches For Experimentally Created Medial Condylar Fractures Of The Equine Third Metacarpal Bone, Saybl Beauton Sprinkle
LSU Master's Theses
Objective -To compare the compression produced in reduction of experimentally created medial condylar fractures using lag screw fixation with medial vs. lateral approach, and to determine the maximum torque at screw failure. Materials and Methods- Twelve (12) pairs (left and right) 3rd metacarpal bones (MC3) were collected from adult (2-7 years) Thoroughbreds euthanized for reasons unrelated to orthopedic disease. Complete parasagittal medial condylar osteotomies were created at a measurement of 9, 13, and 21 mm axial to the epicondylar fossa on four pairs each of cadaveric MC3 bones resulting in fracture fragments measuring 8, 12, and 20 mm in thickness. …
Investigating The Use Of Graphic Organizers For Writing, Laura Nicole Delrose
Investigating The Use Of Graphic Organizers For Writing, Laura Nicole Delrose
LSU Master's Theses
Students are placed under increasing demands for more complex syntax and discourse structure in oral and written language as they age. Children with language and learning disabilities struggle to grasp the organization and relationships between the facts of the topic, making writing an increasingly daunting task. In addition, these students must also master conventions such as vocabulary, spelling, punctuation, and syntax to produce a written essay (Schumaker & Deshler, 2003). This study explored the efficacy of graphic organizers as a strategy to facilitate higher complexity of syntactic and discourse structures in sentence and story formation. After seven weeks of intervention, …
Mechanical Evaluation Of Aluminum Oxide Roughened Screws In Equine Third Metacarpal Bone, Petrisor Baia
Mechanical Evaluation Of Aluminum Oxide Roughened Screws In Equine Third Metacarpal Bone, Petrisor Baia
LSU Master's Theses
ABSTRACT Objectives – To compare the osseointegration of roughened and electropolished 5.5 mm cortical screws used to secure a 4.5 mm broad dynamic compression plate (DCP) in equine third metacarpal (MC3) bones. Study Design – In vivo study Animals – 5 Adult thoroughbred horses (2-7 years old). Methods – For each horse one MC3 was randomly assigned to secure a 4.5 mm broad DCP with 4aluminum oxide (Al2O3) roughened screws on the dorsal mid diaphysis. Four regular electropolished screws used to secure a similar plate on the contralateral limb served as control. They were removed at 12 weeks and the …