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A Novel Strategy Of Controlling Bovine Pneumonic Pasteurellosis: Transfecting The Upper Respiratory Tract Of Cattle With A Gene Coding For The Antimicrobial Peptide Cecropin B, Charles Mitchell Boudreaux
A Novel Strategy Of Controlling Bovine Pneumonic Pasteurellosis: Transfecting The Upper Respiratory Tract Of Cattle With A Gene Coding For The Antimicrobial Peptide Cecropin B, Charles Mitchell Boudreaux
LSU Master's Theses
The very potent antibacterial activity of cecropin B makes it a likely candidate to prevent and/or treat Mannheimia haemolytica 1:A infection in the upper respiratory tract (URT) of cattle. The purpose of this study was to ascertain if the URT could be transfected with a gene coding for the antimicrobial peptide cecropin B. By transfecting cattle with a gene coding for cecropin B, this study attempted to inhibit colonization of a virulent strain of M. haemolytica 1:A in the URT while investigating any possible changes in the indigenous and transient nasal flora. In this study the antibacterial efficacy of cecropin …