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Epigenomic Dysregulation-Mediated Alterations Of Key Biological Pathways And Tumor Immune Evasion Are Hallmarks Of Gingivo-Buccal Oral Cancer, Debodipta Das, Sahana Ghosh, Arindam Maitra, Nidhan K. Biswas, Chinmay K. Panda, Bidyut Roy, Rajiv Sarin, Partha P. Majumder Dec 2019

Epigenomic Dysregulation-Mediated Alterations Of Key Biological Pathways And Tumor Immune Evasion Are Hallmarks Of Gingivo-Buccal Oral Cancer, Debodipta Das, Sahana Ghosh, Arindam Maitra, Nidhan K. Biswas, Chinmay K. Panda, Bidyut Roy, Rajiv Sarin, Partha P. Majumder

Journal Articles

Background: Gingivo-buccal oral squamous cell carcinoma (OSCC-GB) is the most common cancer among men in India and is associated with high mortality. Although OSCC-GB is known to be quite different from tongue cancer in its genomic presentation and its clinical behavior, it is treated identically as tongue cancer. Predictive markers of prognosis and therapy that are specific to OSCC-GB are, therefore, required. Although genomic drivers of OSCC-GB have been identified by whole exome and whole genome sequencing, no epigenome-wide study has been conducted in OSCC-GB; our study has filled this gap, and has discovered and validated epigenomic hallmarks of gingivobuccal …


Socioeconomic Inequality In Life Expectancy In India, Miqdad Asaria, Sumit Mazumdar, Samik Chowdhury, Papiya Mazumdar, Abhiroop Mukhopadhyay, Indrani Gupta May 2019

Socioeconomic Inequality In Life Expectancy In India, Miqdad Asaria, Sumit Mazumdar, Samik Chowdhury, Papiya Mazumdar, Abhiroop Mukhopadhyay, Indrani Gupta

Journal Articles

Introduction Concern for health inequalities is an important driver of health policy in India; however, much of the empirical evidence regarding health inequalities in the country is piecemeal focusing only on specific diseases or on access to particular treatments. This study estimates inequalities in health across the whole life course for the entire Indian population. These estimates are used to calculate the socioeconomic disparities in life expectancy at birth in the population. Methods Population mortality data from the Indian Sample Registration System were combined with data on mortality rates by wealth quintile from the National Family Health Survey to calculate …


Prevalence Of Anaemia And Associated Factors Among Oraon Females Of North 24 Parganas, West Bengal, India, Tanaya Kundu Chowdhury, Subrata K. Roy Mar 2019

Prevalence Of Anaemia And Associated Factors Among Oraon Females Of North 24 Parganas, West Bengal, India, Tanaya Kundu Chowdhury, Subrata K. Roy

Journal Articles

Low haemoglobin level or anaemia is a health problem worldwide especially in developing countries like India. Anaemia is generally higher among indigenous groups compared to general population globally and females are specifically more prone to anaemia. However, studies are inadequate on indigenous groups of India. The aims of the study are to determine the prevalence of anaemia among the female Oraons of North 24 Parganas and to study the association between anaemia and concomitants like socio-demographic and food habit variables. Data have been collected on demographic, socio-economic and food habit variables using well-tested questionnaire from 309 Oraon females living in …


The Association Between Neonatal Death And Facility Birth In Regions Of India, Diane Coffey Jan 2019

The Association Between Neonatal Death And Facility Birth In Regions Of India, Diane Coffey

Journal Articles

BACKGROUND Reducing neonatal mortality in India is critical to achieving the 2030 Sustainable Development Goal of a global neonatal mortality rate (NNM) of no more than 12 per 1,000. Policy efforts to reduce India's NNM, including a large-scale conditional cash transfer program, have focused on promoting birth in health facilities, rather than at home. Between 2005 and 2015, the percentage of facility births doubled, from 40% to 80%. OBJECTIVE We assess evidence for the hypothesis that facility births reduce NNM by using new data from the National Family Health Survey, 2015-2016. METHODS We analyze the association between neonatal death and …