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Review On Personalized Colorectal Cancer, Hussein Ageely Sep 2017

Review On Personalized Colorectal Cancer, Hussein Ageely

Menoufia Medical Journal

Objective The aim of this work was to study biomarkers as indicators of personalization of medicine (PM) for colorectal cancer (CRC). Background PM is considered to be the medicine of the future, as the scope of interest has shifted to patient-specific treatments and remedies. The understanding of human genomics improves the capability of better understanding diseases from the genetic perspective, which is particularly useful in treating CRC. Biomarkers are considered indicators that help in evaluating the prognosis of CRC; in fact, they are now considered to be reliable indices for the diagnosis and leveling of the different stages of cancer. …


Role Of Vitamin D And Its Deficiency In Pediatric Critical Illness, Ahmed A. Khattab, Mohamed A. El Monem Gohar, Nagwan Y. Saleh Sep 2017

Role Of Vitamin D And Its Deficiency In Pediatric Critical Illness, Ahmed A. Khattab, Mohamed A. El Monem Gohar, Nagwan Y. Saleh

Menoufia Medical Journal

Objectives The aim of this study was to assess the role of vitamin D and its deficiency in pediatric critical illness. Methods Medline databases (PubMed, Medscape, ScienceDirect) and all materials available in the Internet from 2003 to 2016. The initial search presented 98 articles, of which 32 fulfilled the inclusion criteria. The articles studied the role of vitamin D and its deficiency in pediatric critical illness. If the studies did not fulfill the inclusion criteria, they were excluded. Study quality assessment included whether ethical approval was obtained, eligibility criteria were specified, there were appropriate controls, there was adequate information, and …


Puberty Disorders And Environmental Disruptors, Alaa A. Dawood, Marwa G. Elsayed, Mostafa G. El Nagar Sep 2017

Puberty Disorders And Environmental Disruptors, Alaa A. Dawood, Marwa G. Elsayed, Mostafa G. El Nagar

Menoufia Medical Journal

Objectives The aim of this study was to perform review studying the effect of different environmental disruptors on normal puberty and occurrence of its disorders. Data sources PubMed, Web of science, Wiley Online Library, Central Authentication Service, and Astrophysics Data System were searched. The search was performed from 1 September 2016 to 15 October 2016. Study selection The initial search presented 250 articles. The researches that met the inclusion criteria were six articled. The articles included physiology of puberty in male and female individuals, puberty disorders, endocrinal disruptors, and effects of endocrinal disruptors on puberty. Data extraction Data from each …


Study Of Osteopontin In Chronic Hepatitis C Virus-Related Liver Cirrhosis, Ashraf G. Dalaa, Eslam M. Rashed, Mohamad A. Holwa Sep 2017

Study Of Osteopontin In Chronic Hepatitis C Virus-Related Liver Cirrhosis, Ashraf G. Dalaa, Eslam M. Rashed, Mohamad A. Holwa

Menoufia Medical Journal

Background Osteopontin (OPN) is a phosphorylated acidic glycoprotein. Its expression increases during pathogenesis of hepatic fibrosis. However, its clinical usefulness in the pathogenesis of liver disease remains obscure. Objective We aimed to evaluate the role of OPN in the degree of hepatic fibrosis in chronic hepatitis C virus (HCV) patients and hepatocellular carcinoma (HCC) patients. Patients and methods This study was conducted on 85 patients who were divided into four groups. Group A consisted of 15 HCV patients with decompensated liver cirrhosis. Group B consisted of 20 HCV patients with HCC. Group C consisted of 35 HCV patients with compensated …


Study Of Association Between Carboxymethyllysine And Circulating Soluble Receptor For Advanced Glycation End Products And Cardiovascular Dysfunction In Nondiabetic Chronic Kidney Disease, Hany Elbarbary, Hassan Abdel-Hady, Heba E. Kasem, Said S. A. Khamis, Seham A. Khodeer Sep 2017

Study Of Association Between Carboxymethyllysine And Circulating Soluble Receptor For Advanced Glycation End Products And Cardiovascular Dysfunction In Nondiabetic Chronic Kidney Disease, Hany Elbarbary, Hassan Abdel-Hady, Heba E. Kasem, Said S. A. Khamis, Seham A. Khodeer

Menoufia Medical Journal

Objective The objective of this study was to evaluate the association between serum advanced glycation end products (AGEs) and their soluble receptors assessed on the basis of carboxymethyllysine (CML) and soluble receptor for advanced glycation end products (sRAGE) and the presence of cardiovascular dysfunction in nondiabetic chronic kidney disease (CKD) patients. Background AGE is involved in left ventricular hypertrophy (LVH) and myocardial damage, whereas sRAGE attenuates the progression of heart disease and prevents death in diabetic and nondiabetic CKD patients. Patients and methods Eighty nondiabetic CKD patients were subclassified according to estimated glomerular filtration rate (GFR) into two subgroups, CKD-3 …


Assessment Of Safety Measures In Hemodialysis Units In Qalyubia Governorate, Hany S. El Barbary, Mahmoud Abd El Aziz Kora, Said S. Ahmed Khamis, Sameh M. Gharib Sep 2017

Assessment Of Safety Measures In Hemodialysis Units In Qalyubia Governorate, Hany S. El Barbary, Mahmoud Abd El Aziz Kora, Said S. Ahmed Khamis, Sameh M. Gharib

Menoufia Medical Journal

Objective The objective of this study was to assess the infection-control measures that are considered one of the most important factors that threaten the safety of the patients and all workers in hemodialysis units. Background Patients undergoing hemodialysis are at risk for multiple infections, and preventing these infections in this high-risk population is a national priority. Patients and methods Nineteen hemodialysis units in Qalyubia Governorate were included in a descriptive study. A questionnaire was developed to assess infection-control measures in units. Results Most of the units studied were clean in general. Most dialysis units had enough basins, soap, and disinfectants …


The Correlation Between Residual Renal Function And Inflammation In Chronic Hemodialysis Patients, Ashraf A. Dawood, Elsayed G. Mahros, Khaled M. Amin El Zorkany, Said S. Ahmed Khamis, Yassin S. Yassin Sep 2017

The Correlation Between Residual Renal Function And Inflammation In Chronic Hemodialysis Patients, Ashraf A. Dawood, Elsayed G. Mahros, Khaled M. Amin El Zorkany, Said S. Ahmed Khamis, Yassin S. Yassin

Menoufia Medical Journal

Objective The aim of the study was to study any possible correlation between inflammation and residual renal function (RRF) in chronic hemodialysis (HD) patients. Background RRF plays an important role in maintaining fluid balance, phosphorus control, nutrition, and removal of middle molecular uremic toxins. Decline of RRF also contributes significantly to anemia, inflammation, and malnutrition in patients on dialysis. Inflammation and activation of acute-phase responses are common in chronic kidney disease patients. The causes of inflammation in HD patients are multifactorial. Inflammatory reaction may originate from several sources, including graft or fistula infections, bioincompatible dialysis membrane, dialysate, endotoxin exposure, back …


Prevalence Of Mineral Bone Disorders Among Hemodialysis Patients In Menoufia Governorate, Egypt, Ahmed F. Abd-Elsattar Saif, Hassan A. E. Ahmed, Khaled M. A. Elzorkany, Yasein S. Yasein Sep 2017

Prevalence Of Mineral Bone Disorders Among Hemodialysis Patients In Menoufia Governorate, Egypt, Ahmed F. Abd-Elsattar Saif, Hassan A. E. Ahmed, Khaled M. A. Elzorkany, Yasein S. Yasein

Menoufia Medical Journal

Objective The aim of this study was to determine the prevalence of mineral bone disorders (MBDs) among hemodialysis (HD) patients in Menoufia Governorate. Background As kidney function declines, there is progressive deterioration in mineral homeostasis manifesting as disruption of serum and tissue concentrations of phosphorus and calcium (Ca), as well as changes in circulating levels of hormones such as parathyroid hormone (PTH). These mineral and endocrine functions are critically important in the regulation of both bone modeling and bone remodeling. Chronic kidney disease-MBD describes a broad clinical syndrome that develops as a systemic disorder of mineral and bone metabolism because …


Serum Peroxiredoxin-3 As A Useful Biomarker For Detection Of Hepatocellular Carcinoma, Alaa E. A. Al-Hamid, Ehab A. A. Al-Atty, Gasser I. Al-Azab, Mohamed H. S. Al-Karafy, Yasser A. A. Alghobashy Sep 2017

Serum Peroxiredoxin-3 As A Useful Biomarker For Detection Of Hepatocellular Carcinoma, Alaa E. A. Al-Hamid, Ehab A. A. Al-Atty, Gasser I. Al-Azab, Mohamed H. S. Al-Karafy, Yasser A. A. Alghobashy

Menoufia Medical Journal

Objective The aim of this study is to evaluate serum peroxiredoxin-3 (PRDX3) as a noninvasive serum marker for the diagnosis of hepatocellular carcinoma (HCC). Background Early diagnosis of HCC is the most important step in successful treatment. However, it is usually rare because of the lack of a highly sensitive and specific biomarker so that the HCC is usually fatal within a few months after diagnosis. PRDX3 is a c-Myc target gene that is required for mitochondrial homeostasis and neoplastic transformation. In our study, we attempted to evaluate the value of PRDX3 as a useful serum biomarker for the detection …


Evaluation Of Serum Prolactin As A Potential Tumor Marker In Hepatocellular Carcinoma, Ashraf E. Abdelghani, Ehab A. Abdelatty, Elsayed I. Elshayeb, Mohamad A. Abouhabal, Yasser A. El Ghobashy Sep 2017

Evaluation Of Serum Prolactin As A Potential Tumor Marker In Hepatocellular Carcinoma, Ashraf E. Abdelghani, Ehab A. Abdelatty, Elsayed I. Elshayeb, Mohamad A. Abouhabal, Yasser A. El Ghobashy

Menoufia Medical Journal

Objectives The aim of this study was to evaluate serum prolactin (PRL) as a potential tumor marker in the detection of hepatocellular carcinoma (HCC). Background HCC ranks fifth among the most prevalent cancers worldwide. In Egypt, the incidence of HCC had been doubling because of hepatitis C viral infection. New serum tumor markers are required for the diagnosis of HCC instead of α-fetoprotein (AFP) (the most widely used marker) due to its poor diagnostic accuracy. Prolactin receptor has been identified in a variety of human tissues, such as the liver. When PRL binds to its receptor, it leads to the …


Vitamin D Receptor Polymorphisms As Predictors Of Response To Interferon/Ribavirin-Based Therapy In Egyptians With Chronic Hepatitis C Infection, A Efat, A El Shormilisy, H Zaghla, M Abd El Hafez, R Mohamed, S Shoeib, S Dina Sep 2017

Vitamin D Receptor Polymorphisms As Predictors Of Response To Interferon/Ribavirin-Based Therapy In Egyptians With Chronic Hepatitis C Infection, A Efat, A El Shormilisy, H Zaghla, M Abd El Hafez, R Mohamed, S Shoeib, S Dina

Menoufia Medical Journal

Objective The aim of the present study was to assess the influence of polymorphisms in vitamin D receptors (VDRs) Fok1 and Apa1 and interleukin 28B rs12979860 C/T on the response to interferon/ribavirin-based therapy in Egyptians with chronic hepatitis C. Background Vitamin D exerts immunomodulatory effects on the host response against infection with hepatitis C virus. Genetic polymorphisms affecting the VDR gene have been implicated in several immune disorders. Patients and methods This retrospective study was conducted on 80 patients who were divided into two groups: group I – the nonresponders group – comprised 40 patients and group II – the …


Assessment Of Serum Betatrophin Concentrations In Patients With Chronic Hepatitis C-Related Liver Cirrhosis, Ahmed R. El-Gazzarah, Amira M. F. Shehata, Moemena S. El-Hamouly, Naglaa S.M. El-Abd Sep 2017

Assessment Of Serum Betatrophin Concentrations In Patients With Chronic Hepatitis C-Related Liver Cirrhosis, Ahmed R. El-Gazzarah, Amira M. F. Shehata, Moemena S. El-Hamouly, Naglaa S.M. El-Abd

Menoufia Medical Journal

Objective The aim of this study was to evaluate serum betatrophin concentrations in patients with chronic hepatitis C-related liver cirrhosis and to explore its potential relations with liver cirrhosis progression and insulin resistance (IR). Background Hepatitis C virus infection is a serious clinical condition that usually progresses to liver cirrhosis. Betatrophin is a newly discovered hormone that has been considered as important regulator of pancreatic β-cell proliferation. Patients and methods We analyzed 70 patients who were diagnosed with chronic hepatitis C-related liver cirrhosis. Patients were assorted into three groups according to Child–Pugh score. In addition, a control group was included …


Study Of Serum Hepcidin In Patients With Chronic Hepatitis C, Ayman M. El Lehleh, Rania A. El Shazly, Rania R. Hamza Sep 2017

Study Of Serum Hepcidin In Patients With Chronic Hepatitis C, Ayman M. El Lehleh, Rania A. El Shazly, Rania R. Hamza

Menoufia Medical Journal

Objective The aim of the present work was to study serum hepcidin in patients with chronic hepatitis C (CHC) as an iron homoeostasis-regulating hormone. Background Persistent infection with hepatitis C virus (HCV) is a major cause of chronic liver disease. Many experimental and clinical studies suggest that excessive iron in CHC is a cofactor promoting the progression of liver damage and increasing the risk for fibrosis. Patients and methods In all, 40 patients with CHC (group 1) and 20 healthy individuals (group 2) who served as a control group were included in this study. All patients were subjected to the …


The Plasma Zinc/Serum Copper Ratio As A Biomarker In Children With Autism Spectrum Disorders, Ghada M. El-Meshad, Mahmoud S. Abou El-Khair, Nashwa M. Moharam, Sameh A. Abd El-Nabi Sep 2017

The Plasma Zinc/Serum Copper Ratio As A Biomarker In Children With Autism Spectrum Disorders, Ghada M. El-Meshad, Mahmoud S. Abou El-Khair, Nashwa M. Moharam, Sameh A. Abd El-Nabi

Menoufia Medical Journal

Objective The aim of this study was to assess the plasma zinc (Zn)/serum copper (Cu) ratio as a biomarker in children with autism spectrum. Background Autism is a complex, behaviorally defined neurodevelopmental disorder characterized by significant impairments in social interaction, verbal and nonverbal communication, and restrictive, repetitive, and stereotypic patterns of behavior. The possible etiologies that precipitate autism symptoms remain controversial in many cases, but both genetic and environmental factors have been implicated. Children with autism spectrum disorder (ASD) appear to be at risk for Zn deficiency, Cu toxicity, and often have low Zn/Cu ratio. Patients and methods The present …


Assessment Of Intellectual Development In Preschool Children In West Of Menoufia Governorate, Egypt, Amany A. Kamal Baker Gomma, Maha A. Mohammed Tawfik, Soheir S. Abou El-Ella, Wafaa M. Abo El-Fotoh Sep 2017

Assessment Of Intellectual Development In Preschool Children In West Of Menoufia Governorate, Egypt, Amany A. Kamal Baker Gomma, Maha A. Mohammed Tawfik, Soheir S. Abou El-Ella, Wafaa M. Abo El-Fotoh

Menoufia Medical Journal

Objective The aim of the present study was to assess intellectual development with screening of other domains of development in preschool children in west of Menoufia Governorate, Egypt. Background Ages and Stages Questionnaires (ASQ) is one of the validated developmental screening tools recommended by the American Academy of Pediatrics for the early detection of developmental delay in preschool children. Patients and methods This cross-sectional study was conducted on 502 children from the age group 24–60 months (304 children were recruited from three city centers and 198 from three villages located in the west of Menoufia Governorate). All children were screened …


Assessment Of Intellectual Development In Preschool Children In The East Of Menoufia Governorate, Egypt, Amany M. Ali Mohammed Elatabany, Maha A. Mohammed Tawfik, Naglaa F. Barseem, Soheir S. Abou El-Ella Sep 2017

Assessment Of Intellectual Development In Preschool Children In The East Of Menoufia Governorate, Egypt, Amany M. Ali Mohammed Elatabany, Maha A. Mohammed Tawfik, Naglaa F. Barseem, Soheir S. Abou El-Ella

Menoufia Medical Journal

Objective The aim of the present study was to assess the intellectual development and other developmental domains in apparently normal preschool children in the east of Menoufia Governorate, Egypt. Background Assessing suspected developmental delays (SDDs) in preschool children is necessary for early intervention and decreasing developmental disabilities, because subtle disabilities, such as language impairment, mild intellectual and learning disabilities, are associated with poor health status. Patients and methods This cross-sectional study included 510 kindergarten children of both sexes chosen from the age group 24–60 months in the east of Menuofia Governorate, Egypt. The mean age of the children was 48.4 …


Critical Illness Myopathy And Polyneuropathy In Children Admitted To The Icu, Ahmed T. Mahmoud, Maha A. Tawfik, Nahla M. Said, Sameh A. Abd El-Naby Abdella Sep 2017

Critical Illness Myopathy And Polyneuropathy In Children Admitted To The Icu, Ahmed T. Mahmoud, Maha A. Tawfik, Nahla M. Said, Sameh A. Abd El-Naby Abdella

Menoufia Medical Journal

Objective The aim of the present study was to detect critical illness polyneuropathy and myopathy in children admitted to the ICU in relation to clinical findings and therapeutic regimen. Background Critical illness polyneuropathy and myopathy is a frequent complication of critical illness, acutely and primarily affecting the motor and sensory axons. This disorder can cause severe limb weakness and prolonged weaning. Patients and methods This study included 75 patients with different diseases admitted to the pediatric ICU at Menoufia University and was conducted for the period of 2 years. The patients were divided into five groups. All patients underwent nerve …


Supportive Aids For Children With Cerebral Palsy, Fatma L. Abdallah Farag, Naglaa F. Barseem, Soheir S. Abou El-Ella Sep 2017

Supportive Aids For Children With Cerebral Palsy, Fatma L. Abdallah Farag, Naglaa F. Barseem, Soheir S. Abou El-Ella

Menoufia Medical Journal

Objective The objectives of this study were to support families of children with cerebral palsy (CP), to improve their lifestyle, and decrease complications through effective interventions. Background CP is the most common physical disability of childhood with variable manifestations and comorbidities; many interventions are pursued to help children with CP. Patients and methods This study was conducted on 75 children with CP (37 males and 38 females), aged 2–15 years, with variable types, degrees, and severity of CP. They were selected randomly from an outpatient pediatric clinic of Menoufia University Hospitals. In the first 4 months, parents of these children …


Celiac, Thyroid Diseases, And Helicobacter Pylori Infection In Association With Type 1 Diabetes Mellitus, Fady M. Elgendy, Heba S. Elsaka, Neama H. Zearaban, Zein A. El-Latif Omar Sep 2017

Celiac, Thyroid Diseases, And Helicobacter Pylori Infection In Association With Type 1 Diabetes Mellitus, Fady M. Elgendy, Heba S. Elsaka, Neama H. Zearaban, Zein A. El-Latif Omar

Menoufia Medical Journal

Objectives To study the association between the diagnostic markers of celiac, thyroid diseases, and Helicobacter pylori infection with type 1 diabetes mellitus (T1DM) and the effect of these diseases on glycemic control. Background T1DM is a chronic metabolic disease characterized by chronic hyperglycemia because of defects in insulin secretion or action or both, and results from the autoimmune destruction of the insulin-producing β-cells in the pancreas. It is commonly associated with autoimmune diseases such as celiac and thyroid diseases. There is a higher prevalence of H. pylori infections in T1DM. Patients and methods This study included 60 patients who presented …


A Study Of Serum Leptin Level In Both Full-Term And Preterm Newborns, Ahmed T. Mahmoud, Dalia M. Ellahony, Maha A. El-Rafea Elbassuoni, Sarah M. A. Elmohsen Sheir Sep 2017

A Study Of Serum Leptin Level In Both Full-Term And Preterm Newborns, Ahmed T. Mahmoud, Dalia M. Ellahony, Maha A. El-Rafea Elbassuoni, Sarah M. A. Elmohsen Sheir

Menoufia Medical Journal

Objective This study aims to compare serum leptin level in preterm and full-term newborns in relation to clinical findings. Background Leptin is a hormone made by fat cells that regulates the amount of fat stored in the body. Fetal and infant nutrition and growth have previously been correlated with disease in adulthood. The inadequate fat tissue in premature infants and infants with intrauterine growth restriction leads to impaired glucose metabolism and insulin resistance. Recent studies refer development of obesity, insulin resistance, and other metabolic disturbances later in life in patients born preterm or small for gestational age. Only few studies …


Effect Of Abnormalities In Leptin Levels On Pituitary-Hypothalamic Axis In Patients With Chronic Hemolytic Anemia, Ahmed T. Lasheen, Asmaa A. Mahmoud, Enas S. Essa, Farida H. El-Rasheidy Sep 2017

Effect Of Abnormalities In Leptin Levels On Pituitary-Hypothalamic Axis In Patients With Chronic Hemolytic Anemia, Ahmed T. Lasheen, Asmaa A. Mahmoud, Enas S. Essa, Farida H. El-Rasheidy

Menoufia Medical Journal

Objective The aim this study was to investigate the serum leptin level and its pathological correlations in children with chronic hemolytic anemia. Background Thalassemia syndromes are hemoglobin disorders that result from significantly reduced or absent synthesis of either α-globin or β-globin chains. This results in chronic hemolytic anemia with high serum ferritin level, which affects serum leptin level through the influence of peripheral adipocytes. Patients and methods This is a comparative observational cross-sectional study carried out on 52 children diagnosed as having β-thalassemia major and 35 healthy children as controls. Patients with thalassemia were recruited from Pediatric Hematology–Oncology Unit of …


Serum Neutrophil Gelatinase-Associated Lipocalin As An Early Biomarker In Acute Kidney Injury In The Pediatric Icu Of Menoufia University, Atef M. Ibrahim, Fady M. El Gendy, Mohammed S. Rizk, Nagwan Y. Saleh Sep 2017

Serum Neutrophil Gelatinase-Associated Lipocalin As An Early Biomarker In Acute Kidney Injury In The Pediatric Icu Of Menoufia University, Atef M. Ibrahim, Fady M. El Gendy, Mohammed S. Rizk, Nagwan Y. Saleh

Menoufia Medical Journal

Objective The objective of the present study was to study the role of neutrophil gelatinase-associated lipocalin (NGAL) as an early biomarker of acute kidney injury (AKI) in the pediatric ICU (PICU) of Menoufia University. Background AKI represents a very devastating problem in critically ill children. Nephrologists are aware of the usefulness of serum NGAL as a biomarker of AKI. Participants and methods This study was carried out at the PICU of Menoufia University Hospital. This study included 80 participants. They were classified into group I (n = 20), including apparently healthy volunteers, and group II (n = 60), …


Anemia Among Pregnant Women Attending The Family Health Center In Kafr Al-Sheikh City, Egypt (An Intervention Study), Hala M. El-Moselhy, Nora A. Khalil, Rasha F. Abd-Elhaleem Sep 2017

Anemia Among Pregnant Women Attending The Family Health Center In Kafr Al-Sheikh City, Egypt (An Intervention Study), Hala M. El-Moselhy, Nora A. Khalil, Rasha F. Abd-Elhaleem

Menoufia Medical Journal

Objective The aim of this study was to assess the prevalence of anemia among pregnant women and estimate the effect of iron supplementation on hemoglobin concentration among the anemic participants. Background Anemia in pregnancy is a major health problem. It is the most common cause of maternal mortality. Severe anemia is associated with preterm birth, low birth weights, and a fetus small for gestational age. Most of the complications are preventable through increased awareness and improving health status of pregnant women. Participants and methods This was a cross-sectional study conducted in the family health center of Kafr Al-Sheikh city. The …


Burnout And Quality Of Life Among Physicians In Primary Healthcare Facilities In Egypt: A Cross-Sectional Study, Dalia H. Mohamed, Nagwa N. Hegazy, Tagraeed M. Farahat Sep 2017

Burnout And Quality Of Life Among Physicians In Primary Healthcare Facilities In Egypt: A Cross-Sectional Study, Dalia H. Mohamed, Nagwa N. Hegazy, Tagraeed M. Farahat

Menoufia Medical Journal

Objectives The aim of this study was to deter mine the prevalence of burnout among physicians in primary healthcare facilities and explore the relationship between perceived quality of life and levels of burnout among the physicians. Background Healthcare workers, particularly physicians, are exposed to high levels of stress at work. Burnout syndrome may increase the risk for medical errors and affects the physician's quality of life. Patients and methods The study was a cross-sectional one conducted on 76 physicians in El Kanater El Kharia primary healthcare units and centers in Qalyubia Governorate, Egypt. It was conducted during a period of …


Anemia Among The Elderly Attending A Family Health Center, Menoufia University, Egypt, Enshad Badawy, Enshad E. Mohammed, Hala M. Shaeen, Nagwa N. Hegazy Sep 2017

Anemia Among The Elderly Attending A Family Health Center, Menoufia University, Egypt, Enshad Badawy, Enshad E. Mohammed, Hala M. Shaeen, Nagwa N. Hegazy

Menoufia Medical Journal

Objective The aim of the present study was to assess the prevalence of anemia and the associated cognitive and nutritional status among the elderly attending the Munshat Sultan Family Health Center. Background Anemia is a common health problem with serious consequences among the elderly. Multiple studies demonstrate that anemia is an independent risk factor for increased morbidity and mortality among the elderly. Patients and methods This case-controlled, cross-sectional study was conducted on 200 elderly persons of both sexes recruited from Munshat Sultan Family Health Center, Menoufia district, Menoufia governorate, Egypt. Initially, the sample size was calculated to be 163, which …


Undiagnosed Diabetes Among Adult Attendants Of A Rural Primary Healthcare Center In Menoufia Governorate, Ahmed M. Zahran, Aml A. Salama, Asma S. Beddah Sep 2017

Undiagnosed Diabetes Among Adult Attendants Of A Rural Primary Healthcare Center In Menoufia Governorate, Ahmed M. Zahran, Aml A. Salama, Asma S. Beddah

Menoufia Medical Journal

Objective The present study aimed to estimate the prevalence of undiagnosed diabetes in adult attendants of a primary healthcare center in a rural area. Background The prevalence of diabetes is rapidly increasing worldwide. T2DM may remain undetected for many years, leading to severe complications and healthcare costs. Patients and methods We carried out a cross-sectional study on 1255 cases, with a mean age of 38.9±11.16 years. All participants were subjected to history taking, complete medical examination, and laboratory investigations (measurement of fasting blood glucose level and 2-h postprandial blood glucose level). We then compared our findings between the diabetic group …


Risk Factors Of Lung Cancer Among Women In Menoufia Governorate, Egypt, Marwa K. Abo Aianh, Nagwa N. Hegazy, Naser M. Abd Elbary Sep 2017

Risk Factors Of Lung Cancer Among Women In Menoufia Governorate, Egypt, Marwa K. Abo Aianh, Nagwa N. Hegazy, Naser M. Abd Elbary

Menoufia Medical Journal

Objectives The objectives of this study were to assess the risk factors and distribution of lung cancer among women in Menoufia governorate. Background Lung cancer used to be thought of as a man's disease, but women now account for almost half of new cases and deaths from lung cancer. Patients and methods The study was a case–control study. Women were selected according to the following inclusion criteria: adult females above 18 years, histopathological proof lung cancer, controlled comorbidity. The recruited participants were 60 women from the clinical oncology hospital records from January 2011 to December 2015 in Menoufia University, Shebin …


Prevalence And Risk Factors Of Musculoskeletal Disorders Among Natural Gas Field Workers, Heba K. Allama, Mahmoud E. Abu Salema, Mohamed M. Hasan El-Kholyb, Omaima A. Mahrousa, Zeinab A. Kasemya Sep 2017

Prevalence And Risk Factors Of Musculoskeletal Disorders Among Natural Gas Field Workers, Heba K. Allama, Mahmoud E. Abu Salema, Mohamed M. Hasan El-Kholyb, Omaima A. Mahrousa, Zeinab A. Kasemya

Menoufia Medical Journal

Objectives This work aimed at studying the prevalence of musculoskeletal disorders among workers in natural gas fields and studying the relationship between the resultant health disorders and the working conditions. Background Workers at natural gas fields are continuously exposed to numerous hazardous materials and working conditions that place them at continuous risk of injury or death. Participants and methods A cross-sectional study carried out on 172 workers in one of the natural gas fields in Egypt. Results The prevalence of regional musculoskeletal pain was 47.7% in the studied workers. Low back pain was the most prevalent (30.5%), followed by knee …


Hepatitis C As A Risk Factor For Coronary Artery Disease In Silent Myocardial Ischemia, Ashraf G. Dala, Mohammad H. Badr, Ramy M. Omar, Waleed Abdou Hamed Sep 2017

Hepatitis C As A Risk Factor For Coronary Artery Disease In Silent Myocardial Ischemia, Ashraf G. Dala, Mohammad H. Badr, Ramy M. Omar, Waleed Abdou Hamed

Menoufia Medical Journal

Objective The aim of the present study was to evaluate the relationship between seropositivity of hepatitis C virus (HCV) and the severity of coronary artery disease in silent myocardial ischemic patients. Background Silent myocardial ischemia is defined as an objective evidence of myocardial ischemia occurring in the absence of symptoms. HCV was found to have a positive association with carotid artery plaque. Patients and methods We investigated 50 patients with silent myocardial ischemia. Patients were divided into two groups (group A included 25 HCV-seropositive patients and group B included 25 HCV-seronegative patients). Patients were subjected to history taking, clinical examination, …


Assessment Of Right Atrium Function In Hypertrophic Cardiomyopathy By Speckle-Tracking Echocardiography, Ghada M. Sultan, Hala M. Badran, Hatem A. Mohamed, Naglaa F. Ahmed Sep 2017

Assessment Of Right Atrium Function In Hypertrophic Cardiomyopathy By Speckle-Tracking Echocardiography, Ghada M. Sultan, Hala M. Badran, Hatem A. Mohamed, Naglaa F. Ahmed

Menoufia Medical Journal

Objective We sought to evaluate the regional and global longitudinal strain/strain rate (SR) profiles in the right atrial (RA) wall to quantify RA function in hypertrophic cardiomyopathy. Background According to previous studies on the deformational properties of the left atrium, the systolic strain and SRs represent the atrial reservoir function and the early and late diastolic SRs show the conduit and booster functions, respectively. Patients and methods Speckle-tracking echocardiography of the RA, right ventricle, and left ventricle was acquired from apical four-chamber view in 118 hypertrophic cardiomyopathic patients and 33 healthy individuals; all had normal left ventricular systolic function. Subendocardium …