Open Access. Powered by Scholars. Published by Universities.®
- Institution
- Keyword
-
- Stroke epidemiology (12)
- Brazil (10)
- Cardiovascular epidemiology (10)
- Stroke (9)
- Obesity and diabetes epidemiology (6)
-
- Internal medicine and geriatrics (5)
- Mortality (5)
- Cerebrovascular (3)
- Education and public health (3)
- Prevalence (3)
- Cerebral infarction (2)
- Cohort studies (2)
- WHO Steps (2)
- Adiposity (1)
- Autopsy (1)
- Cancer epidemiology (1)
- Cardiovascular diseases (1)
- Cerebrovascular diseases (1)
- Children (1)
- Diabetes (1)
- ELSA-Brasil (1)
- Elderly (1)
- Epidemiological transition (1)
- Epidemiology (1)
- Heart disease (1)
- Hepatitis (1)
- High blood pressure (1)
- Methods (1)
- Obesity (1)
- Race (1)
Articles 1 - 29 of 29
Full-Text Articles in Entire DC Network
Setting Up The Longitudinal Study For Adult Health (Elsa-Brasil), Paulo A. Lotufo
Setting Up The Longitudinal Study For Adult Health (Elsa-Brasil), Paulo A. Lotufo
Paulo A Lotufo
Baseline data collection of the Brazilian Longitudinal Study for Adult Health (ELSA-Brasil) was complete by December 2010. A cohort of 15,105 subjects has been followed up on incident events at six study sites for three years. The ELSA-Brasil is remarkable for its large sample size and wide variety of data collected to investigate biological and social determinants of cardiovascular diseases and diabetes mellitus in adults in Brazil. A group of Brazilian experts in chronic noncommunicable disease research started planning this study project in 2004. It was launched at a meeting on August 20 to 21, 2004 held at the Universidade …
Brazilian Longitudinal Study Of Adult Health (Elsa-Brasil): Objectives And Design., Paulo A. Lotufo
Brazilian Longitudinal Study Of Adult Health (Elsa-Brasil): Objectives And Design., Paulo A. Lotufo
Paulo A Lotufo
The Brazilian Longitudinal Study of Adult Health (ELSA-Brasil) aims to contribute relevant information with respect to the development and progression of clinical and subclinical chronic diseases, particularly cardiovascular diseases and diabetes. In this report, the authors delineate the study's objectives, principal methodological features, and timeline. At baseline, ELSA-Brasil enrolled 15,105 civil servants from 5 universities and 1 research institute. The baseline examination (2008-2010) included detailed interviews, clinical and anthropometric examinations, an oral glucose tolerance test, overnight urine collection, a 12-lead resting electrocardiogram, measurement of carotid intima-media thickness, echocardiography, measurement of pulse wave velocity, hepatic ultrasonography, retinal fundus photography, and an …
Hypothyroidism In The Elderly, Paulo A. Lotufo
Hypothyroidism In The Elderly, Paulo A. Lotufo
Paulo A Lotufo
An overview adressing observational and randomized clinical trials about hypothyroidism in the elderly.
Chronic Non-Communicable Diseases In Brazil: Priorities For Disease Management And Research, Bruce B. Duncan, Dora Chor, Estela M. Aquino, Isabela M. Bensenor, J.Geraldo Mill, M.Ines Schmidt, Paulo A. Lotufo, Alvaro Vigo, Sandhi M. Barreto
Chronic Non-Communicable Diseases In Brazil: Priorities For Disease Management And Research, Bruce B. Duncan, Dora Chor, Estela M. Aquino, Isabela M. Bensenor, J.Geraldo Mill, M.Ines Schmidt, Paulo A. Lotufo, Alvaro Vigo, Sandhi M. Barreto
Paulo A Lotufo
Chronic Non-Communicable Diseases are the main source of disease burden in Brazil. In 2011, the Brazilian Ministry of Health launched the Strategic Plan of Action for Management of Chronic Non-Communicable Diseases focusing on population-based interventions to manage cardiovascular diseases, diabetes, cancer, and chronic respiratory diseases mainly through fi ghting tobacco use, unhealthy diets, physical inactivity and the harmful use of alcohol. Although a signifi cant number of scientifi c studies on chronic diseases and their risk factors have been undertaken in Brazil, few are of cohort design. In this context, the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil), a cohort …
A Reappraisal Of Stroke Mortality Trends In Brazil (1979 To 2009), Paulo A. Lotufo
A Reappraisal Of Stroke Mortality Trends In Brazil (1979 To 2009), Paulo A. Lotufo
Paulo A Lotufo
Background: Brazil has the highest cerebrovascular death rate in the Western Hemisphere. We investigated temporal trends according to gender and stroke subtypes. Methods: We analysed mortality rates between 1979 and 2009 for different stroke subtypes. Data were stratified by sex and age (35–74 y). The annual percent change (APC) and significant changes in the trends were identified with joinpoint Poisson regression. The average annual percent change (AAPC) for 2005-09 was presented because that period had the best quality of information. Results: After excluding deaths due to stroke sequels, for men, the APCs (95% confidence intervals) were: 1979-84: 0.7 (-0.8 to …
Prevalence Of Thyroid Disorders Among Older People: Results From The São Paulo Ageing & Health Study, Paulo A. Lotufo
Prevalence Of Thyroid Disorders Among Older People: Results From The São Paulo Ageing & Health Study, Paulo A. Lotufo
Paulo A Lotufo
This study aimed to estimate prevalence of thyroid disorders in the São Paulo Ageing & Health Study, an epidemiological study addressing several health-adverse outcomes among elderly people living in a poor area of São Paulo, Brazil. All participants answered a questionnaire and had a blood sample collected to assess levels of tireotropic hormone and free-thyroxine. Among 1,373 people (60.8% women), prevalence rates (95% confidence interval) for thyroid dysfunction (%) were: overt hyperthyroidism, 0.7% (0.2-1.1) [women: 0.8% (0.2-1.5); men: 0.4% (0.01-0.9)]; overt hypothyroidism, 5.7% (4.5-6.9) [women: 5.9% (4.3-7.5); men: 5.4% (3.5-7.3)]; subclinical hyperthyroidism, 2.4% (1.6-3.2) [women: 2.8% (1.6-3.9); men: 1.9% (0.7-3.0)]; …
A Stepwise Approach To Stroke Surveillance In Brazil: The Emma (Estudo De Mortalidade E Morbidade Do Acidente Vascular Cerebral) Study, Paulo A. Lotufo
A Stepwise Approach To Stroke Surveillance In Brazil: The Emma (Estudo De Mortalidade E Morbidade Do Acidente Vascular Cerebral) Study, Paulo A. Lotufo
Paulo A Lotufo
Background: Stroke mortality rates in Brazil are the highest in the Americas. Deaths from cerebrovascular disease surpass coronary heart disease. Aim: To verify stroke mortality rates and morbidity in an area of Sa˜o Paulo, Brazil, using the World Health Organization Stepwise Approach to Stroke Surveillance. Methods: We used the World Health Organization Stepwise Approach to Stroke Surveillance structure of stroke surveillance. The hospital-based data comprised fatal and nonfatal stroke (Step 1). We gathered stroke-related mortality data in the community using World Health Organization questionnaires (Step 2). The questionnaire determining stroke prevalence was activated door to door in a family-healthprogramme neighbourhood …
Validation Of A Stroke Symptom Questionnaire For Epidemiological Surveys., Paulo A. Lotufo
Validation Of A Stroke Symptom Questionnaire For Epidemiological Surveys., Paulo A. Lotufo
Paulo A Lotufo
CONTEXT AND OBJECTIVE:Stroke is a relevant issue within public health and requires epidemiological surveillance tools. The aim here was to validate a questionnaire for evaluating individuals with stroke symptoms in the Stroke Morbidity and Mortality Study (Estudo de Mortalidade e Morbidade do Acidente Vascular Cerebral, EMMA), São Paulo, Brazil.DESIGN AND SETTING:This was a cross-sectional study performed among a sample of the inhabitants of Butantã, an area in the western zone of the city of São Paulo.METHODS:For all households in the coverage area of a primary healthcare unit, household members over the age of 35 years answered a stroke symptom questionnaire …
Gender Differences Of Case-Fatality Rate In A Brazilian Stroke Registry, Paulo A. Lotufo
Gender Differences Of Case-Fatality Rate In A Brazilian Stroke Registry, Paulo A. Lotufo
Paulo A Lotufo
No abstract provided.
Subclinical Hyperthyroidism And Dementia: The Sao Paulo Ageing & Health Study (Spah), Paulo A. Lotufo
Subclinical Hyperthyroidism And Dementia: The Sao Paulo Ageing & Health Study (Spah), Paulo A. Lotufo
Paulo A Lotufo
Background: Several epidemiologic studies have shown a possible association between thyroid function and cognitive decline. Our aim was to evaluate the association of subclinical hyperthyroidism and dementia in a population sample of older people. Methods: A cross-sectional study - São Paulo Ageing & Health Study (SPAH) - in a population sample of low-income elderly people ≥ 65 years-old to evaluate presence of subclinical thyroid disease as a risk factor for dementia. Thyroid function was assessed using thyrotropic hormone and free-thyroxine as well as routine use of thyroid hormones or antithyroid medications. Cases of dementia were assessed using a harmonized one-phase …
Stroke Mortality In Brazil: One Example Of Delayed Epidemiological Cardiovascular Transition, Paulo A. Lotufo
Stroke Mortality In Brazil: One Example Of Delayed Epidemiological Cardiovascular Transition, Paulo A. Lotufo
Paulo A Lotufo
No abstract provided.
Prevalence Of Electrocardiographic Findings In Elderly Individuals: The Sao Paulo Aging & Health Study, Paulo A. Lotufo
Prevalence Of Electrocardiographic Findings In Elderly Individuals: The Sao Paulo Aging & Health Study, Paulo A. Lotufo
Paulo A Lotufo
Background: The determination of the prevalence of electrocardiographic alterations in the older age strata of the Brazilian population represents important information with clinical and epidemiological purpose. Objective:To verify the prevalence rates of atrial fibrillation, enlarged Q/QS waves (Minnesota code 1.1-1.2) and left bundle branch block. Methods: In a population-based study, 1,524 participants (921 women and 603 men) aged > 65 years and living in Sao Paulo, Brazil, were submitted to electrocardiographic assessment at rest as well as anthropometric and blood pressure measurements, in addition to fasting blood collection for the measurement of glycemia, total cholesterol and fractions. Results: The age-adjusted prevalence …
Nutritional Evaluation Of The Patients With Head And Neck Squamous Cell Carcinoma [Portuguese], Paulo A. Lotufo
Nutritional Evaluation Of The Patients With Head And Neck Squamous Cell Carcinoma [Portuguese], Paulo A. Lotufo
Paulo A Lotufo
Patients with head and neck squamous cell carcinoma (HNSCC) usually present nutritional disorders, secondary to the upper aerodigestive tract involvement or due to the treatment sequels. Objective: To assess the nutritional status of patients with HNSCC in different phases of the disease treatment. Methods: Cross-sectional study with 155 patients divided in 4 groups: 103 patients with HNSCC (29 before treatment, 47 post-treatment with no recurrence and 27 post treatment with recurrent disease) and 52 controls without HNSCC. Clinical and epidemiological data were collected and a nutrition assessment was performed from anthropometric parameters (weight, height and Body Mass Index – BMI), …
Patterns Of Viral Load In Chronic Hepatitis B Patients In Brazil And Their Association Withalt Levels And Hbeag Status, Paulo A. Lotufo
Patterns Of Viral Load In Chronic Hepatitis B Patients In Brazil And Their Association Withalt Levels And Hbeag Status, Paulo A. Lotufo
Paulo A Lotufo
Serum hepatitis B virus (HBV) DNA level is a predictor of the development of cirrhosis and hepatocellular carcinoma in chronic hepatitis B patients. Nevertheless, the distribution of viral load levels in chronic HBV patients in Brazil has yet to be described. This cross-sectional study included 564 participants selected in nine Brazilian cities located in four of the five regions of the country using the database of a medical diagnostics company. Admission criteria included hepatitis B surface antigen seropositivity, availability of HBV viral load samples and age >or=18 years. Males comprised 64.5% of the study population. Mean age was 43.7 years. …
Measurements Of Adiposity And High Blood Pressure Among Children And Adolescents Living In Belo Horizonte, Paulo A. Lotufo
Measurements Of Adiposity And High Blood Pressure Among Children And Adolescents Living In Belo Horizonte, Paulo A. Lotufo
Paulo A Lotufo
Abstract Objective: To verify an association, if it exists, between obesity and blood pressure raised beyond the 90th percentile in children and adolescents, and to determine the measure of adiposity that best correlates with blood pressure in these subjects. Design: Cross-sectional study. Setting: A school-based study in Belo Horizonte, Brazil. Participants: We selected randomly 1,403 students, aged from 6 to 18 years, from 545,046 students attending 521 public and private schools. Those selected completed the study. Main measures of outcome: We recorded the weight, height, skin fold in the triceps, subscapular, and suprailiac areas, waist and hip circumference, body-mass index, …
Estudo Longitudinal De Saúde Do Adulto -Elsa-Brasil [English], Paulo A. Lotufo
Estudo Longitudinal De Saúde Do Adulto -Elsa-Brasil [English], Paulo A. Lotufo
Paulo A Lotufo
Presentation update on September, 2011.
Framingham Score For Cardiovascular Diseases [Portuguese], Paulo A. Lotufo
Framingham Score For Cardiovascular Diseases [Portuguese], Paulo A. Lotufo
Paulo A Lotufo
Review about cardiovascular risk factors.
Race, Gender And Stroke Subtypes Mortality In Sao Paulo, Brazil., Paulo A. Lotufo
Race, Gender And Stroke Subtypes Mortality In Sao Paulo, Brazil., Paulo A. Lotufo
Paulo A Lotufo
Stroke mortality rates have a discrepant distribution according to socioeconomic variables as social exclusion in Brazil. Recently, data from race has been available from the official health statistics considering five categories: White, Mixed, Black, Asian and Native. We addressed in the city of São Paulo, Brazil, an analysis of cerebrovascular mortality according to race (excluding Asian and Native due to small number of events) and gender during 1999-2001 for people aged 30 to 79 years-old. For all cerebrovascular diseases, age-adjusted mortality rates (x 100,000) for men were higher for Black (150.2), intermediate for Mixed (124.2) and lower for White (104.5) …
Sunshine And Suicide At The Tropic Of Capricorn, São Paulo, Brazil, 1996–2004, Paulo A. Lotufo
Sunshine And Suicide At The Tropic Of Capricorn, São Paulo, Brazil, 1996–2004, Paulo A. Lotufo
Paulo A Lotufo
Several studies have confi rmed seasonal variation in suicide rates according to hours of sunshine. The suicide pattern was assessed in São Paulo, southeastern Brazil, at the tropic of Capricorn from 1996 to 2004. Poisson regression was employed to estimate parameters of seasonality, as well as to verify associations for each day between daylight duration and suicide. During the nine-year study period, there were 3,984 suicides (76.9% in men; median age=38.7 years old). Seasonal averages of suicides were similar, as were monthly averages. Poisson regression did not reveal any association between suicide rates and hours of sunshine (p=0.45) for both …
Air Pollutants And Respiratory Symptoms Among Adults, Paulo A. Lotufo
Air Pollutants And Respiratory Symptoms Among Adults, Paulo A. Lotufo
Paulo A Lotufo
Air pollutants are associated with adverse respiratory effects mainly in susceptible groups such as children, elderly people and people with pre-existent respiratory disease. This study was designed to assess the impact of the inorganic composition of particulate matter on 33 adult asthmatics respiratory functions in São Paulo city, Brazil. From May to July 2002, fine and coarse particulate matter fractions were collected and trace metals (Fe2+, Mn2+, Zn2+, Pb2+, Cu2+) and major ions (Na+, Mg2+, K+, Ca2+, NH4 +, Cl-, NO3-, SO42-) composition was determined in each aqueous-extract fraction by Atomic Absorption Spectrometry with Graphite Furnace (AAS-GF) and Ion Chromatography, …
Additional Cardiovascular Risk Factors Associated With Excess Weigth In Children And Adolescents. The Belo Horizonte Heart Study, Paulo A. Lotufo
Additional Cardiovascular Risk Factors Associated With Excess Weigth In Children And Adolescents. The Belo Horizonte Heart Study, Paulo A. Lotufo
Paulo A Lotufo
OBJECTIVE: To examine the association of overweight and obesity with physical activity, blood pressure (BP) and serum lipid profiles. METHODS Epidemiologic investigation of 1,450 students, between the ages of 6 and 18, in the city of Belo Horizonte, MG. Data: weight, height, BP, skinfold thickness, waist circumference, physical activity, total cholesterol (TC), LDL-c, HDL-c, and dietary habits. RESULTS The prevalence rates for overweight and obesity were 8.4% and 3.1%, respectively. In relation to the students in the lower quartile (Q1) of the distribution of subscapular skinfold, the students in the upper quartile (Q4) presented a 3.7 times higher risk (odds …
Higher Burden Of Hemorrhagic Stroke Among Women An Autopsy-Based Study In São Paulo, Brazil, Paulo A. Lotufo
Higher Burden Of Hemorrhagic Stroke Among Women An Autopsy-Based Study In São Paulo, Brazil, Paulo A. Lotufo
Paulo A Lotufo
The aim of this study was to verify the gender difference in sudden cardiovascular death, mainly comparing brain infarction and hemorrhagic stroke. We analyzed 970 autopsy cases from a total of 3,802 nonviolent deaths (448 considered as sudden deaths, 296 undetermined, and 226 non-sudden deaths) including patients aged 30–69 years. All cardiovascular diseases were responsible for 69% of sudden deaths, and all types of stroke for only 14%. The proportions of sudden death for all cardiovascular diseases, coronary heart disease and ischemic stroke deaths were similar for both sexes. However, sudden deaths due to all types of stroke (women 20.0%; …
Stroke In Brazil: A Neglected Disease, Paulo A. Lotufo
Stroke In Brazil: A Neglected Disease, Paulo A. Lotufo
Paulo A Lotufo
The turning point in the transition from infectious diseases to non-transmittable diseases in Brazil occurred in the 1960s, taking the country as a whole. However, considering the main cities, such as São Paulo and Rio de Janeiro, cerebrovascular disease mortality rates have surpassed the “old cardiovascular diseases” like rheumatic heart disease and syphilitic aortic disease since the end of World War II. Until the end of the 1980s, the burden of stroke mortality observed in the main Brazilian cities was higher than in the United States, Canada and western European countries, and similar to what is observed in Eastern Europe …
Trends Of Stroke Subtypes Mortality In Sao Paulo, Brazil (1996-2003), Paulo A. Lotufo, Isabela M. Bensenor
Trends Of Stroke Subtypes Mortality In Sao Paulo, Brazil (1996-2003), Paulo A. Lotufo, Isabela M. Bensenor
Paulo A Lotufo
The decline of stroke mortality rates has been described in Brazil; however, there is no data about stroke subtypes. We described the changes of stroke mortality rates in the city of Sao Paulo (1996-2003) emphasizing intracerebral hemorrhage and cerebral infarction. We categorized mortality data by gender and 10-year age-strata from 30 to 79 years-old. For men, an annual reduction of all types of stroke (-3.9%), and of stroke subtypes as intracerebral hemorrhage (-3.0%) and cerebral infarction was observ e d (-2.7%) as well as, a decline of ill-defined stroke (-7.4%). For women, a decline was observed for all types of …
Progress Testing: Evaluation Of Four Years Of Application In The School Of Medicine, University Of São Paulo, Paulo A. Lotufo
Progress Testing: Evaluation Of Four Years Of Application In The School Of Medicine, University Of São Paulo, Paulo A. Lotufo
Paulo A Lotufo
Progress testing is a longitudinal tool for evaluating knowledge gains during the medical school years. Objectives: (1) To implement progress testing as a form of routine evaluation; (2) to verify whether cognitive gain is a continuous variable or not; and (3) to evaluate whether there is loss of knowledge relating to basic sciences in the final years of medical school. Methods: A progress test was applied twice a year to all students from 2001 to 2004. The mean percentage score was calculated for each school year, employing ANOVA with post hoc Bonferroni test evaluation for each test. Results:Progress testing was …
Stroke Mortality In Sao Paulo (1997-2003). A Description Using The Tenth Revision Of The International Classification Of Diseases, Paulo A. Lotufo
Stroke Mortality In Sao Paulo (1997-2003). A Description Using The Tenth Revision Of The International Classification Of Diseases, Paulo A. Lotufo
Paulo A Lotufo
Stroke mortality rates are higher in Brazil when compared to other countries. The city of Sao Paulo has a good system of mortality surveillance that allow us to describe the epidemiology of the stroke in the city. Our aim was to describe the stroke mortality pattern by gender and age characterizing the ischemic/hemorrhagic ratio. We categorized mortality data by gender and a 10-year age-strata from 30-39 years-old to 70-79 years-old. To avoid random variations, we calculated the mean of all deaths occurred during the period of 1997 to 2003. Mortality rates were calculated using the population from the Brazilian National …
Brazil Is Getting Older: Some Lessons From The Bambuí Health And Aging Study, Paulo A. Lotufo
Brazil Is Getting Older: Some Lessons From The Bambuí Health And Aging Study, Paulo A. Lotufo
Paulo A Lotufo
No abstract provided.
Winter And Cardiovascular Mortality, Paulo A. Lotufo
Winter And Cardiovascular Mortality, Paulo A. Lotufo
Paulo A Lotufo
Winter time and mortality due to heart failure in Sao Paulo, Brazil during the 1930's.
Premature Mortality From Chronic Diseases In Brazil. [Portuguese], Paulo A. Lotufo
Premature Mortality From Chronic Diseases In Brazil. [Portuguese], Paulo A. Lotufo
Paulo A Lotufo
This thesis evaluated the pattern of chronic diaseases mortality in Brazil during the 1980´s. We studied the age strata from 35-years-old to 64-years-old to analyze the chronic disease-related premature deaths. The questions are the following: 1. Are chronic disease-related premature deaths higher in Brazil than abroad? 2. Is premature mortality higher in males than in females? Which is the best indicator for premature mortality, age-adjusted rates or the impact of deaths elimination by Chiang’ method? Are there geographic or temporal differences in chronic diseases mortality rates among Brazilian metropolitan areas? 5. Which are the social and economics determinants of chronic …