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Do Resistance Training Exercises Help Improve Symptoms Of Depression Or Depression Scores?, Michalia Humphrey

PCOM Physician Assistant Studies Student Scholarship

OBJECTIVE: The objective of this selective EBM review is to determine whether or not resistance training exercises help improve symptoms of depression and/or depression scores.

STUDY DESIGN: Review of three randomized control trials (RTCs), all published from 2009 to present and all written in the English language.

DATA SOURCES: Data sources included peer reviewed articles that were published on PubMed and were selected based on their relevance to the research question and patient outcomes measured.

OUTCOME MEASURED: The clinical outcome of depression symptom improvement with resistance training exercises was measured in these studies using the Center for Epidemiological Studies Depression …

Is Ketamine Effective In Reducing Depressive Symptoms In Adults With Treatment-Resistant Major Depressive Disorder?, Andrew J. Suplicki

PCOM Physician Assistant Studies Student Scholarship

Objective: The objective of this selective EBM review is to determine whether or not ketamine is effective in reducing depressive symptoms in adults with treatment-resistant major depressive disorder.

Study Design: A systematic review of 3 randomized, double-blind placebo controlled trials performed in or after the year 2016.

Data Sources: All 3 studies published in peer-reviewed journals found on PubMed and Cochrane Collection.

Outcome Measures: The studies utilized quantitative scales, either the Montgomery-Asberg Depression Scale (MADRS) or Hamilton Depression Rating Scales (HAMD) for the POEM, depressive symptoms.

Results: George et al. (Am J Geriatr Psychiatry. 2017;25(11):1199-1209. doi: 10.1016/j.jagp.2017.06.007) did show significant …

Is Psilocybin An Effective Treatment To Reduce Depression And Anxiety In Cancer Patients With A Diagnosis Of An Anxiety Disorder, Mood Disorder, And/Or Stress Disorder?, Brooke Reichenbach

PCOM Physician Assistant Studies Student Scholarship

Objective: The objective of this selective EBM review is to determine whether or not psilocybin is an effective treatment to reduce depression and anxiety in cancer patients with a diagnosis of an anxiety disorder, mood disorder, and/or stress disorder.

Study design: Systematic review of three cross-over randomized placebo-controlled trials published in peer reviewed journals between 2010-2016.

Data sources: All articles were published in English and were selected from Cochrane Collaboration and PubMed based on if they were relevant to my clinical question and included patient-oriented outcomes (POEMs).

Outcomes measured: Outcomes measured included self-reported anxiety and depression via the State-Trait Anxiety …