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What Are The Effects Of Curcumin, Whether Alone Or In Conjunction With Alternative Therapy, On Major Depressive Disorder?, Preeti Jain

PCOM Physician Assistant Studies Student Scholarship

Objective: The objective of this selective EBM review is to determine whether or not curcumin, whether alone or in conjunction with alternative therapy, has an effect on Major Depressive Disorder (MDD).

Study Design: Systematic review of 3 primary studies, published between 2013 and 2016.

Data Sources: Three randomized control trials (RCT), two of which were double blind. These studies were found using Cochrane Systematic Reviews and PubMed.

Outcomes Measured: Outcome for all three articles are symptomatic changes of MDD. The outcomes measured were Patient-Oriented Evidence that Matters (POEMS) and were assessed using various self-rated tools.

Results: All three studies demonstrated …

Are The Use Of Probiotics An Effective Treatment For Relieving Symptoms Of Depression In Adults?, Olynda B. Mileon-Etuk

PCOM Physician Assistant Studies Student Scholarship

OBJECTIVE: The objective of this selective EBM is to determine whether or not, “Are the use of antibiotics an effective treatment for relieving symptoms of depression in adults?”

STUDY DESIGN: Review of three English language primary studies, published between 2010- 2016.

DATA SOURCES: Three randomized controlled trials (RCTs) were found using PubMed- NCBI. These studies analyzed the effectiveness of probiotics in adults with symptoms of depression.

OUTCOME MEASURED: The main outcome measured was improvement of symptoms of depression after the administration of probiotic supplements. Outcomes were assessed using data from self-reported questionnaires, which include the Hopkins Symptom Checklist (HSCL-90), Hospital …