Digital Commons Network^™

Vaccines At The Intersection Of Religion And Politics, Charles Downey

Master's Theses

Vaccine hesitancy – a delay in acceptance or refusal of vaccines despite their availability – is a rising threat to global health and has increased in recent years in higher income countries. This is a complex phenomenon with the potential to undo decades of progress toward eradicating communicable diseases. The recent COVID-19 pandemic introduced a new wave of vaccine hesitancy, with evangelical Christians as leading actors in the movement away from vaccines in the United States. The present study investigated factors related to vaccine hesitancy and sources of health-related information among members of evangelical Christian churches in and around Hattiesburg, …

Exploring The Relationships Between Food Insecurity, Wic Participation, Early Life Feeding Practices, Diversity Of Dietary Exposures, And Diet Quality In The First Two Years Of Life, Vivian M. Drewelow

Master's Theses

Diet quality during early childhood is a strong predictor of mental and physical outcomes, as well as future diet quality. Although many factors determine diet quality during childhood, food insecurity is a significant predictor of lower diet quality. On the other hand, participation in nutrition assistant programs, such as the Special Supplemental Nutrition Program for Women, Infants, and Children (WIC) is a significant predictor of higher diet quality. In addition, specific feeding practices, including timing of complementary food and beverage (CFB) introduction, types of CFB introduced early, and diversity of dietary exposures (DD), in the first year may predict future …

Fine-Tuning Gene Expression: A Novel Therapeutic Approach For Rett Syndrome, Yewon Rhee

Master's Theses

Rett Syndrome (RTT) is a neurodevelopmental disorder that is characterized by a myriad of debilitating symptoms impacting nearly every aspect of life, including motor and gait impairment, social and cognitive deficits, as well as seizures and breathing abnormalities. RTT is caused by X-linked de novo loss-of-function mutations in the methyl-CpG binding protein 2 gene (MECP2), which is an essential epigenetic modulator. Any cure for RTT must directly target MECP2, a highly dosage-sensitive gene. This thesis developed a novel MECP2-targeted therapeutic approach using site-blocking antisense oligonucleotides to prevent microRNA-induced repression of MECP2, allowing fine-tuned control of gene expression. Here we report …

Development Of An Advanced Step Counting Algorithm With Integrated Activity Detection For Free Living Environments, Paige M. Dolan

Master's Theses

Physical activity plays a crucial role in maintaining overall health and reducing the risk of various chronic diseases. Step counting has emerged as a popular method for assessing physical activity levels, given its simplicity and ease of use. However, accurately measuring step counts in free-living environments presents significant challenges, with most activity trackers exhibiting a percent error above 20%. This study aims to address these challenges by creating a machine learning algorithm that leverages activity labels to improve step count accuracy in real-world conditions. Two approaches to balancing data were used: one employed a simpler oversampling technique, while the other …

Deciphering The Contribution Of Microglia To Neurodegeneration In Friedreich's Ataxia, Sydney N. Gillette

Master's Theses

Friedreich's ataxia (FRDA) is the most prevalent inherited ataxia, affecting one in every 50,000 individuals in the United States. This hereditary condition is caused by an abnormal GAA trinucleotide repeat expansion within the first intron of the frataxin gene resulting in decreased levels of the frataxin protein (FXN). Insufficient cellular frataxin levels results in iron accumulation, increased reactive oxygen species production and mitochondrial dysfunction. Tissues most heavily impacted are those most dependent on oxidative phosphorylation as an energy source and include the nervous system and muscle tissue. This is evident in the clinical phenotype which includes muscle weakness, ataxia, neurodegeneration …

Accessible Real-Time Eye-Gaze Tracking For Neurocognitive Health Assessments, A Multimodal Web-Based Approach, Daniel C. Tisdale

Master's Theses

We introduce a novel integration of real-time, predictive eye-gaze tracking models into a multimodal dialogue system tailored for remote health assessments. This system is designed to be highly accessible requiring only a conventional webcam for video input along with minimal cursor interaction and utilizes engaging gaze-based tasks that can be performed directly in a web browser. We have crafted dynamic subsystems that capture high-quality data efficiently and maintain quality through instances of user attrition and incomplete calls. Additionally, these subsystems are designed with the foresight to allow for future re-analysis using improved predictive models, as well as enable the creation …

Design And Implementation Of A Vision-Based Deep-Learning Protocol For Kinematic Feature Extraction With Application To Stroke Rehabilitation, Juan Diego Luna Inga

Master's Theses

Stroke is a leading cause of long-term disability, affecting thousands of individuals annually and significantly impairing their mobility, independence, and quality of life. Traditional methods for assessing motor impairments are often costly and invasive, creating substantial barriers to effective rehabilitation. This thesis explores the use of DeepLabCut (DLC), a deep-learning-based pose estimation tool, to extract clinically meaningful kinematic features from video data of stroke survivors with upper-extremity (UE) impairments.

To conduct this investigation, a specialized protocol was developed to tailor DLC for analyzing movements characteristic of UE impairments in stroke survivors. This protocol was validated through comparative analysis using peak …

Red Raspberries Attenuate Blood Glucose Spike Of A High Glycemic Load Breakfast Cereal, Dante J. Martin

Master's Theses

Blood glucose (BG) spikes increase chronic disease risk in those with and without diabetes. The fiber and phytonutrient content of fruit, such as raspberries has the potential to attenuate the BG spike of a high glycemic load (HGL) meal. We examined the effect of red raspberries (RRs) on the BG spike when added to a HGL meal. In this randomized cross-over trial, 16 university students were given breakfast cereal and almond milk (control), the control breakfast with 140g added RRs, and the control breakfast with sugar equivalent to the sugar content of the RRs (50% sugar increase from control). Meals …

Barriers To Gluten-Free Diet Adherence And How They Relate To Quality Of Life And Self-Efficacy In College Students With Celiac Disease, Caitlin Elizabeth Wall

Master's Theses

Celiac disease (CD) is a chronic, autoimmune disorder with an increasing global prevalence. As the only current treatment is a strict gluten-free diet (GFD), adherence is imperative to maintain optimal health in individuals with the disease. There are many potential barriers to GFD adherence, including social, mental, and financial difficulties. College also presents a unique set of challenges for students with CD that may not be experienced by those without the disease. The purpose of this study was to determine the potential barriers to GFD adherence experienced by college students with celiac disease in the United States. This study also …

Impact Of Temperature On Children’S Nutrition: A Comparative Study Of Three Ecological Regions Of Nepal, Prakriti Shakya

Master's Theses

Nutrition obtained during the growth period of childhood significantly influences long-term well-being and overall productivity, ultimately contributing to the economy of a society. However, weather shocks can wreak havoc by damaging crops, changing yields of important crops and disrupting market access, which directly impacts the food intake of both adults and children. When these adverse events occur during childhood, short term and long term inadequacy in nutrition as well as disease incidence can cause malnutrition leading to stunted growth and cognitive impairment that may persist into adulthood, affecting the labor market and increasing health expenditure. To address this issue, we …

The Impact Of Female Political Leadership On Intimate Partner Violence In India, Khushboo Patel

Master's Theses

Abstract:

This study employs an instrumental variable approach to examine the impact of female political leadership on women’s experiences of Intimate Partner Violence (IPV). It finds that in rural areas with more female leaders, incidents of sexual and psychological IPV increase. The analysis investigates the drivers behind this impact, revealing that entrenched gender norms and expectations, such as a husband’s preference for more sons, may exacerbate IPV. Additionally, despite the increase in female leaders, attitudes toward violence remain largely unchanged. These findings highlight the need for research and policy initiatives that not only encourage female political participation but also specifically …

Matrilineal Ethnic Affiliation And Female Empowerment: Investigating Attitudes Towards Female Autonomy And Health In Ivorian Households, Martine Hind Stølan

Master's Theses

Kinship structure is a fundamental aspect of anthropology, however, there is still a gap in literature on its impact on economic research, particularly regarding female autonomy and health. This study aims to address this gap by examining the influence of matrilineal ethnic affiliation on attitudes towards female autonomy and health within Ivorian households. Using data from the 2011 IPUMS Demographic and Health Survey for the Ivory Coast, using female responses, this study investigates the complex dynamics shaping attitudes towards female autonomy and access to health care. Analysis on these aspects is done using ordinary least squares (OLS) and logistic estimations. …

Supplemental High-Tech Augmentative And Alternative Communication Experiences: A Study On Graduate Student Self-Efficacy, Confidence, And Knowledge With Pre-Service Training, Emily Sikes

Master's Theses

Providing assessment and intervention with high-tech augmentative and alternative communication is within the scope of practice of American Speech-Language Pathologists (SLPS). Therefore, SLPs should be able to properly identify and implement assessment, intervention, and caregiver coaching strategies in this area of practice. Due to the lack of confidence ratings of current SLPs in providing assessment and intervention in AAC that is found in current research, this study was designed to find plausible solutions for which confidence ratings can be increased beginning at the graduate level of a Speech-Pathology Master’s program. The researchers sought to answer the following questions: “Do students …

Gestalt Language Processing In Accredited Communication Sciences And Disorders Programs, William Harris

Master's Theses

The language development and usage of autistic individuals has become a controversial topic in many of the disciplines and professions providing support to these individuals. As a result, two theories of language processing have been proposed. Analytical language processing suggests that children process and develop language from its most simple form, a phoneme, to its most complex form, a word or phrase. However, the theory of gestalt language processing proposes that some children may instead extract larger, more complex language such as whole words and phrases first and break it down to the simpler language. Gestalt language processing is often …

Athletic Identity Association And Prospective Basic Psychological Needs Satisfaction Predict Attitudes Of Collegiate Athletes Toward Seeking Help From The Athletic Department, Allie Zerr

Master's Theses

There is an epidemic of mental health issues that has begun to be more openly talked about in college athletics. In 2022, the National Collegiate Athletic Association has found that college student-athletes are now 1.5-2 times more likely to report struggling with mental health than ever before. Previous research has shown a significant association with basic psychological needs satisfaction and overall psychological well-being. Furthermore, the purpose of this study was to investigate the possible ways that reported of autonomy, competence, and relatedness need satisfaction predicted whether athletes would seek mental health services and identify how athletic identity plays into this …

The Relationship Between Social Cognition And Team Cohesion In Collegiate Athletes, Jessica Pegg

Master's Theses

Thesis Abstract

Purpose: This study aimed to investigate the relationship between social cognition and team cohesion in Division III collegiate athletes. Methods: A total of 103 athletes from SUNY Cortland participated. Two questionnaires were used: social cognition was assessed via the Tromsø Social Intelligence Scale (TSIS), and team cohesion was assessed via the Group Environment Questionnaire (GEQ). The two questionnaires, along with demographics, were completed online. Analysis: Pearson’s bivariate correlations were analyzed to assess the relationships among TSIS total score, GEQ total score, and GEQ social cohesion for the total sample and separately by sports season and sports type. Linear …

The Role Of B Cell Activation State And Sex In Aryl Hydrocarbon Receptor Mediated Induction Of Chemokine Receptor 9 And Alpha4beta7 Expression In Vitro, Logan Bauerle

Master's Theses

Defense of mucosal tissues from microbial infection and allergy is reliant on continual production of antibodies. The aryl hydrocarbon receptor (AhR) is known to regulate B cell development and is associated with suppression of systemic humoral immunity. Recent attention has been paid to the role of the AhR in altering expression of cell adhesion molecules (CAMs). B cells express CAMs and chemokine receptors to migrate around the body for localized secretion of antibodies. AhR agonists promote B cell migration to the small intestine through upregulation of chemokine receptor 9 (CCR9) and integrin α₄β₇. Both the AhR …

Does Appearance Matter? The Relationship Of Perceived Body Size And Physical Appearance On Students' Attraction To Physical Activity At Recess, Danielle Belcher

Master's Theses

Drastic declines in recess physical activity (PA) have been observed within recent years (Center for Disease Control (CDC), 2017). Due to recess’ discretionary nature, psychosocial variables associated with PA are predictors of students’ PA levels. Recess is also a time of heightened bullying occurrences (Vaillancourt et al., 2010). Appearance-based bullying is the most common type of victimization that occurs in schools, transpiring more often in children with larger body max indexes (BMI), and possibly altering students’ physical self-perceptions. Physical self-perceptions have been shown to impact PA motivation, however, it is still unknown the extent to which appearance-based bullying, body size, …

How Speech-Language Pathologists Account For Self-Determination Across The Progression Of Dementia, Emilee Mcgahee

Master's Theses

Dementia diagnoses are continuing to increase, with the number of diagnoses expected to reach 231 million globally by 2050 (World Alzheimer’s Report, 2019). With this comes a greater need for Speech-Language Pathologists (SLPs) who are able to best treat those who are diagnosed. Providing person-centered and strengths-based treatment approaches for people with dementia (PWD) has been proven to increase positive engagement responses while decreasing negative engagement responses (Skrainer et al., 2007). The primary objective of this research study was to assess treatment approaches used by SLPs in dementia care setting, along with how SLPs provide person-centered dementia treatment throughout the …

Kinetic And Kinematic Effect Of Flag-Carrying On Referee Agility And Sprinting Performance, William Reed

Master's Theses

Within competitive soccer, assistant referees are expected to keep up with the top speed of players on the field, despite being hindered mechanically by a flag held down at their side. This ability to keep up with speed-of-play can determine effectiveness of calls on the field, yet while being tested, referees are not required to replicate the game-like state of flag-carrying. The purpose of this study was to examine kinetic and kinematic effects of flag-carrying within sprinting and change-of-direction performance in assistant referees to better inform training programs and testing protocols. 18 male referees (mean age 32.11 ± 9.08 years) …

Evaluating A Common Book Program's Effect On Gains In Knowledge And Position Toward Sustainability In The Nutrition Professions, Hallie Lanice Shupe

Master's Theses

A Common Reader Program, also called a common book, summer reading, or a one-book program, has been reported to enhance the college educational experience yet appears to have been underutilized by colleges and universities. In the case of health sciences, there can be great benefits in having students learn from the literature not typically found in textbooks used in the curricula. Common reader programs allow for different teaching methods to be implemented and using multiple teaching methods in a single program can be beneficial. In nutrition and dietetics (ND) programs there is a need for additional education regarding sustainability in …

Parental Beliefs About Mental Health And Available Support, Michele O'Geare

Master's Theses

This study adds information to the field by investigating the relationship between parental beliefs about mental health and the services they use to support their child’s mental health issues. The study targeted 224 parents from a private K-12 school in the Midwest. The school was selected because of the many students from diverse backgrounds. This study does not intend to influence parental beliefs but investigates ways families seek support for their children. Descriptive statistics like mean and standard deviation were combined to analyze quantitative data used to interpret parents’ beliefs toward mental health and the use of specific mental health …

The Impact Of High Temperatures On Child Anthropometric Outcomes Worldwide, Natalia A. Cancino Garcia

Master's Theses

High temperatures caused by climate change significantly impact society, including child nutrition. Our research focuses on the impact of high temperatures on the anthropometric outcomes of children aged 1 to 5 in 54 countries worldwide. We analyze the historical climate and anthropometric data to evaluate the effect of high temperature on weight-for-age (WAZ) and weight-for-height (WHZ) in children. Results indicate that high temperatures negatively affect child nutrition, particularly in areas above 20°C, and children in rural areas are more vulnerable. The impact of monthly temperature on child anthropometric outcomes varies across countries, regions, and cultural practices. Economic status alone is …

Using Noninvasive Calibrated Cuff Plethysmography To Observe The Effects Of Cold-Water Immersion On Arterial Compliance, Rita M. Grigorian

Master's Theses

As the prevalence of cardiovascular diseases continues to exponentially grow in populations across the globe, the necessity of determining underlying factors, effective methods of diagnoses, and universally available preventive measures also grows. Early detection of endothelial dysfunction, a proven precursor of cardiovascular diseases, can be extremely impactful in encouraging preventative measures and early intervention before medical conditions become chronic. In recent years, ice plunging, a form of cryotherapy involving full body immersion in cold water, has gained popularity within circles of fitness and health practitioners, gaining the interest of people of all backgrounds. Certain parallels observed between the human physiological …

Nanodiscs: A Novel Approach To The Study Of The Methionine Abc Transporter System, Michael T. Winslow

Master's Theses

Membrane transporter proteins play the vital role of moving compounds in and out of the cell and are essential for all living organisms. ATP Binding Cassette (ABC) family transporters function both as importers and exporters in prokaryotes. MetNI is an E. coli Type I ABC transporter responsible for the uptake of methionine into the cytosol from the cell periplasmic space through the cell membrane to maintain intracellular methionine pools. ABC transporters, like other membrane proteins, are most often mechanistically and structurally studied in vitro, solubilized by detergents. However, detergent micelles may affect the conformational changes of membrane proteins relative to …

Predictive Ability Of A 3d Body Scanning Mobile Application For Metabolic Health Risk, Caleb Brandner

Master's Theses

There is an increasing prevalence of obesity within the US and rising rates of metabolic syndrome among those aged 20-39 concurrent with a decrease in the reception of primary care. Limitations to healthcare including access, cost, and availability, highlighting the need for simple, efficient, and accessible cardiometabolic health risk screening. Given the surge in smartphone ownership over the last decade, this study sought to determine the predictive ability of a mobile 3D-optical (3DO) body composition assessment application in determining metabolic health risk. A total of 62 participants (female: 36) underwent traditional anthropometric measurements, 3DO body scanning using a smartphone application, …

Effects Of Concussion And Visuomotor Metrics On Nhl Performance: An Explainable Ai Approach, Michael T. Moschitto

Master's Theses

Cognitive motor integration (CMI), the simultaneous coordination between cerebral function and motor output, is known to deteriorate following a mild traumatic brain injury (mTBI). This thesis explores the relationship between mTBI, CMI, and the performance of elite athletes in the National Hockey League (NHL). The approach focuses on examining the predictive value of various supervised Machine Learning (ML) models with an emphasis on Explainable Artificial Intelligence (XAI) models. Since the ML solution is intended to complement human scouting decisions, we evaluate the experiments based on both interpretability and accuracy on a limited class imbalanced dataset. The contributions of this research …

Tempers Rising: The Effect Of Heat On Spite, Jake C. Cosgrove

Master's Theses

The relationship between heat and harmful outcomes is well documented, with research connecting various adverse economic outcomes to the climate. In the presence of increasing global warming and climate change, understanding why the climate leads to negative economic outcomes is essential for forming peaceful institutions of the future. We study how behavioral economic outcomes change in the presence of heat through a lab experiment involving 1,110 observations conducted in five different countries. This paper specifically focuses on the social preference outcome of spite. We find that increased time exposure to the treatment effect of heat is required to elicit an …

An Investigation Of Resistance Training Behavior, Non-Specific Psychological Distress, And Perceived Barriers To Resistance Training In Self-Identifying Female Undergraduate Students, Jody Sobel

Master's Theses

The prevalence and severity of depression symptoms amongst college students, specifically female identifying undergraduate students, is worrisome. There is a great deal of research that suggests a relationship between exercise, specifically resistance training (RT), and mental health. That said, current literature suggests that many female identifying students are not engaging due to perceived barriers. This, perhaps because of the plethora of barriers one can perceive. The purpose of this study was multifold 1) to examine the prevalence and severity of non-specific psychological distress; 2) to determine if there were differences between Kessler 6 Non-Specific Psychological Distress Scale (K6) categories (i.e., …

Murine Tbk1 Is Required By Flt3+ Leukemia Stem Cells Yet Dispensable In Homeostatic Hematopoiesis, Austin Runde

Master's Theses

The TANK-binding kinase 1 (TBK1) is a cytoplasmic, serine/threonine kinase and a critical activator of the innate immune system. Reports have implicated TBK1 as a promoter of multiple cancer types. Acute myeloid leukemia (AML) is a cancer arising from the hematopoietic stem/progenitor cells (HSPCs). Although ~70% of AML patients achieve complete remission with chemotherapy, at least half will relapse due to the failure to eradicate leukemia stem cells (LSCs). As our previous data indicate the TLR-TAK1/TICAM-1 axes regulate LSCs, we suspect TBK1 also regulates LSCs. To study TBK1 in AML, we generated tamoxifen-inducible, Tbk1-knockout (Tbk1NULL) mice and Tbk1NULL MLL-AF9+ mouse …