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Dietary Inclusion Of Enriched Chicken Bone Broth Prevents Trigeminal Sensitization Meditated By Early Life Stress, Orion Peterson
Dietary Inclusion Of Enriched Chicken Bone Broth Prevents Trigeminal Sensitization Meditated By Early Life Stress, Orion Peterson
MSU Graduate Theses
Early life stress is considered a risk factor for development of migraine, which is a prevalent painful neurological disorder involving sensitization and activation of trigeminal neurons, and irritable bowel syndrome, a condition often comorbid with chronic migraine. The focus of my study was to determine the effects of early life stress and dietary inclusion of enriched chicken bone broth on trigeminal nociceptor sensitization and the gut microbiota. Adult Sprague-Dawley male “sender” rats subjected to primary traumatic stress were placed next to breeding or pregnant female rats that served as “receiver” rats (secondary traumatic stress) and in proximity to the offspring …
Electrogenerated Chemiluminescence Of Transition Metal Octaethylporphyrin And Tetraphenylporphyrin/Tri-N-Propylamine System, Jamie Lee Gray
Electrogenerated Chemiluminescence Of Transition Metal Octaethylporphyrin And Tetraphenylporphyrin/Tri-N-Propylamine System, Jamie Lee Gray
MSU Graduate Theses
The electrogenerated chemiluminescence (ECL) of octaethylporphyrin (OEP), tetraphenylporphyrin (TPP) and a series of metal-ligand porphyrin complexes (Zinc, Copper, Palladium, Platinum, Ruthenium, Vanadium, Cobalt and Nickel) in CH2Cl2 is reported. ECL was generated upon sweep to positive potentials using tri-n-propylamine (TPrA) as an oxidative-reductive coreactant. ECL efficiencies were between 0.010 and 0.770 using Ru(bpy)3(PF6)2 (bpy = 2,2’-bpyridine) as a relative standard (ecl = 1). The ECL intensity peaks at a potential corresponding to oxidation of the complexes and TPrA, suggesting that the same excited states are formed in both photoluminescence and ECL. Although the ECL was weaker than corresponding PL efficiencies, …
Enhanced Production Of Pro-Il-1Βeta Contributes To Immunopathology During The Coinfection Of Influenza A Virus And Streptococcus Pneumoniae, Angeline E. Rodriguez
Enhanced Production Of Pro-Il-1Βeta Contributes To Immunopathology During The Coinfection Of Influenza A Virus And Streptococcus Pneumoniae, Angeline E. Rodriguez
MSU Graduate Theses
Viral bacterial coinfections are known to cause severe pneumonia, especially in the elderly and in pediatric patients. Antibiotics like β-Lactams kill the bacteria but fail to improve symptoms suggesting a faulty immune system may play an important role in the disease. Interleukin-1β (IL-1β) is an important immune signaling cytokine responsible for inflammation. It exists as an inactive precursor that can be activated by caspase-1 containing inflammasomes (multi-protein complex). Influenza A virus (IAV) and Streptococcus pneumoniae (S. pneumoniae) activate the inflammasome through the NOD-like receptor protein NLRP3 and/or AIM2. Previous reports in mice indicate that IL-1β levels are dramatically …
Controlling The Uncontrollable: Understanding The Relationships Between Psychological Distress, Physical Impairment, And Acceptance Among Women With Gynecological Cancer, Kirby L. Williams
Controlling The Uncontrollable: Understanding The Relationships Between Psychological Distress, Physical Impairment, And Acceptance Among Women With Gynecological Cancer, Kirby L. Williams
MSU Graduate Theses
As women age, the risk for being diagnosed with any gynecological cancer increases. Despite outnumbering the number of breast cancer diagnoses in a given year, there are significantly fewer studies addressing gynecological cancers. Treatment for gynecological cancers can be incredibly debilitating, both physically and psychologically. Although previous studies have evaluated and shown a relationship between physical impairment and perceived control on psychological distress in cancer patients during treatment, none have evaluated the influence of willingness and acceptance. The present study sought to expand this theory by assessing 25 gynecological cancer participants via self-report measures. Utilizing structural equation modelling, a moderated …
Investigation Into The Role Of Platelet Derived Growth Factor (Pdgf) In Type I Collagen Glomerulopathy, Isaac C. Springer
Investigation Into The Role Of Platelet Derived Growth Factor (Pdgf) In Type I Collagen Glomerulopathy, Isaac C. Springer
MSU Graduate Theses
Progressive accumulation of collagen and extracellular matrix (ECM) proteins within renal glomeruli have implications for or result in renal fibrosis and glomerulosclerosis, with both events culminating in renal failure. To model this accumulation the Col1a2-deficient mouse model was used. The Col1a2-deficientmouse model is characterized by a mutation in the a2(I) chain, preventing incorporation into the type I collagen molecule. As a result, an α1(I) collagen chain incorporates into the collagen triple helix forming homotrimeric type I collagen, as opposed to heterotrimeric type I collagen. This change is due to the secondary wound healing response in response to ECM accumulation, …
Levels Of Professional Stress In Missouri State University Sport Coaches, James Edgar Seratt
Levels Of Professional Stress In Missouri State University Sport Coaches, James Edgar Seratt
MSU Graduate Theses
Due to the particular nature of collegiate sport coaching, that is, the need to secure victories at all costs in order to ensure job security, collegiate sport coaches are a population that are likely to experience high levels of personal and professional stress. Previous research has indicated that coaches at all levels of competition, experience degrees and levels of stress similar to those experienced by individuals in other high stress professions, including police officers, medical professionals, and teachers. Furthermore, research has indicated that high levels of stress are positively correlated with decreased work performance. For this research, 45 Missouri State …
Temporal And Intensity Relationships Between Physical Activity And Drunkorexia Behaviors Among First-Year College Students, Robert E. Booker Jr
Temporal And Intensity Relationships Between Physical Activity And Drunkorexia Behaviors Among First-Year College Students, Robert E. Booker Jr
MSU Graduate Theses
The purpose of this research was to examine the temporal element of physical activity (PA) in relation to drunkorexia occurrences and how PA intensities predict severity of drunkorexia behaviors. No research, to our knowledge, has explored if students are proactively or reactively engaging in PA to reduce the effects of calories consumed from alcohol nor if there exists a dose relationship among PA intensities (sedentary, moderate, vigorous) and severity of drunkorexia behaviors. A convenience sample of first-year college students living in residence halls was selected to participate in the current study. Participants completed an online survey including The Drunkorexia Motives …