Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 1 of 1
Full-Text Articles in Entire DC Network
Ace And Ucp2 Gene Polymorphisms And Their Association With Baseline And Exercise-Related Changes In The Functional Performance Of Older Adults, Justin W. Keogh, Barry Palmer, Denise Taylor, Andrew Kilding
Ace And Ucp2 Gene Polymorphisms And Their Association With Baseline And Exercise-Related Changes In The Functional Performance Of Older Adults, Justin W. Keogh, Barry Palmer, Denise Taylor, Andrew Kilding
Justin Keogh
Maintaining high levels of physical function is an important aspect of successful ageing. While muscle mass and strength contribute to functional performance in older adults, little is known about the possible genetic basis for the heterogeneity of physical function in older adults and in how older adults respond to exercise. Two genes that have possible roles in determining levels of muscle mass, strength and function in young and older adults are angiotensin-converting enzyme (ACE) and mitochondrial uncoupling protein 2 (UCP2). This study examined whether polymorphisms in these two individual genes were associated with baseline functional performance levels and/or the training-related …