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Evaluation Of Selenomethionine Entrapped In Nanoparticles For Oral Supplementation Using In Vitro, Ex Vivo And In Vivo Models, Shane Forde, Giuliana Vozza, David J. Brayden, Jesus Maria Frias, Sinead M. Ryan
Evaluation Of Selenomethionine Entrapped In Nanoparticles For Oral Supplementation Using In Vitro, Ex Vivo And In Vivo Models, Shane Forde, Giuliana Vozza, David J. Brayden, Jesus Maria Frias, Sinead M. Ryan
Articles
Selenium methionine (Se Met) is an essential micronutrient required for normal body function and is associated with additional health benefits. However, oral administration of Se Met can be challenging due to its purported narrow therapeutic index, low oral bioavailability, and high susceptibility to oxidation. To address these issues, Se Met was entrapped in z e i n-coated nanoparticles made from chitosan using an ionic gelation formulation. The high stability of both the Se Met and s e l e n o methionine nanoparticles (Se Met-NPs) was established using cultured human intestinal and liver epithelial cells, rat liver homogenates, and rat …
Tio2-Mwcnt Nanohybrid: Cytotoxicity, Protein Corona Formation And Cellular Internalisation In Rtg-2 Fish Cell Line, Gabriela Helena Da Silva, Lidiane Silva Franqui, Marcelo A. De Farias, Vera Lucia S.S. De Castro, Hugh Byrne, Diego S.T. Martinez, Regina T.R. Monteiro, Alan Casey
Tio2-Mwcnt Nanohybrid: Cytotoxicity, Protein Corona Formation And Cellular Internalisation In Rtg-2 Fish Cell Line, Gabriela Helena Da Silva, Lidiane Silva Franqui, Marcelo A. De Farias, Vera Lucia S.S. De Castro, Hugh Byrne, Diego S.T. Martinez, Regina T.R. Monteiro, Alan Casey
Articles
Titanium dioxide nanoparticles-multiwalled carbon nanotubes (TiO2-MWCNT) nanohydrid has an enhanced photocatalytic activity across the visible light with promising applications in environmental remediation, solar energy devices and antimicrobial technologies. However, it is necessary to evaluate the toxicological effects of TiO2-MWCNT towards safe and sustainable development of nanohybrids. In this work, we studied the cytotoxicity, protein corona formation and cellular internalisation of TiO2-MWCNT on fibroblasts derived from gonadal rainbow trout tissue (RTG-2) for the first time. This nanohydrid did not show any toxicity effect on RTG-2 cells up to 100 mg L-1 after 24 h of exposure as monitored by alamar blue, …
Extraction Yield And Biological Activity Of Phycobiliproteins From Porphyridium Purpureum Using Atmospheric Cold Plasma Discharge And Jet Systems, Shaba Noore, Brijesh K. Tiwari, Anet R. Jambrak, Josipa Dukic, Janith Wanigasekara, James Curtin, Claudio Fuentes-Grunewald, Colm P. O’Donnell
Extraction Yield And Biological Activity Of Phycobiliproteins From Porphyridium Purpureum Using Atmospheric Cold Plasma Discharge And Jet Systems, Shaba Noore, Brijesh K. Tiwari, Anet R. Jambrak, Josipa Dukic, Janith Wanigasekara, James Curtin, Claudio Fuentes-Grunewald, Colm P. O’Donnell
Articles
Phycobiliproteins (PBPs) extracted from Porphyridium purpureum (P.p) have bioactive properties and are widely used as ingredients in nutraceutical and food applications. This study investigated the use of two cold plasma systems, namely cold plasma discharge system (CPDS) and cold plasma jet system (CPJS), for the aqueous extraction of PBPs from P. p. Three types of PBPs, namely phycoerythrin (PE), phycocyanin (PC) and allophycocyanin (APC) were identified in the crude extracts obtained. The highest PBPs extraction yield (11.31 ± 1.02 mg/g DW P. p) was obtained from CPDS treated samples at 25 kV using N2 for 9 min. CPDS treatments were …
Valorisation Of Phytochemical From Sitka Spruce (Picea Sitchensis) Needles: Impact Of Ultrasound/Microwave-Assisted Extraction, Hadil Alaydi, Xianglu Zhu, Julie Mondala, Brijesh K. Tiwari, Bibha Kumari, James Curtin, Peter Downey, Michelle Mckeon-Bennett, Tanya Beletskaya
Valorisation Of Phytochemical From Sitka Spruce (Picea Sitchensis) Needles: Impact Of Ultrasound/Microwave-Assisted Extraction, Hadil Alaydi, Xianglu Zhu, Julie Mondala, Brijesh K. Tiwari, Bibha Kumari, James Curtin, Peter Downey, Michelle Mckeon-Bennett, Tanya Beletskaya
Articles
Sitka spruce (Picea sitchensis) needles contain a variety of bioactive compounds including phenolic compounds and flavonoids, many of which have been used in the cosmetic, pharmaceutical, and food industries. This study aimed to investigate the effects of novel extraction techniques, including ultrasound-assisted extraction (UAE), microwave-assisted extraction (MAE) and simultaneous ultrasound–microwave-assisted extraction (UMAE) on the recovery of phenolic, flavonoids and associated antioxidant and anti-cancer properties from Sitka spruce (Picea sitchensis) needles. The ferric reducing antioxidant power (FRAP) assay was used to evaluate the antioxidant capacity, and the Alamar Blue assay using the human brain glioblastoma cancer cell line (U-251 MG) was …