Digital Commons Network^™

The Role Of Angiogenesis-Inducing Micrornas In Vascular Tissue Engineering, May-Hui Ding, Eloy G. Lozoya, Rene N. Rico, Sue Anne Chew

Health & Biomedical Sciences Faculty Publications and Presentations

Angiogenesis is an important process in tissue repair and regeneration as blood vessels are integral to supply nutrients to a functioning tissue. In this review, the application of microRNAs (miRNAs) or anti-miRNAs that can induce angiogenesis to aid in blood vessel formation for vascular tissue engineering in ischemic diseases such as peripheral arterial disease and stroke, cardiac diseases, and skin and bone tissue engineering is discussed. Endothelial cells (ECs) form the endothelium of the blood vessel and are recognized as the primary cell type that drives angiogenesis and studied in the applications that were reviewed. Besides ECs, mesenchymal stem cells …

Nuclear And Chloroplast Dnas Reveal Diverse Origins And Mis-Identifications Of Juniperus Cultivars From Windsor Gardens, Uk, Part 3 Of 3, Robert P. Adams, Sam T. Johnson, John Anderson, Keith Rushforth, Nicolas Valentin, Andrea E. Schwarzbach, Sonja Siljak-Yakovlev

Health & Biomedical Sciences Faculty Publications and Presentations

Ploidy was determined for 15 plants labeled as Juniperus squamata at the Windsor Gardens, UK and revealed 12 were tetraploids (2n=4x=44) and 3 were diploids (2n=2x=22). nrDNA (ITS) and cp DNA sequencing the tetraploids found: 4 J. squamata (4x); 4 J. tibetica (4x) x J. squamata (4x); 2 J. sabina var. balkanensis (4x) x J. squamata (4x); and one J. chinensis var. sargentii (4x) x J. squamata (4x). Sequencing the 3 diploids revealed: 2 J. pingii (2x) x J. pingii (2x); and 1 J. pingii (2x)? x J. komarovii(2x)? Ploidy analyses of 18 additional cultivars, putatively from Juniperus davurica, J. …

Brain-Wide Structural And Functional Disruption In Mice With Oligodendrocyte-Specific Nf1 Deletion Is Rescued By Inhibition Of Nitric Oxide Synthase, Jad Asleh, Ben Shofty, Nadav Cohen, Alexandra Kavushansky, Alejandro Lopez-Juarez, Shlomi Constantini, Nancy Ratner, Itamar Kahn

Health & Biomedical Sciences Faculty Publications and Presentations

Neurofibromin gene (NF1) mutation causes neurofibromatosis type 1 (NF1), a disorder in which brain white matter deficits identified by neuroimaging are common, yet of unknown cellular etiology. In mice, Nf1 loss in adult oligodendrocytes causes myelin decompaction and increases oligodendrocyte nitric oxide (NO) levels. Nitric oxide synthase (NOS) inhibitors rescue this pathology. Whether oligodendrocyte pathology is sufficient to affect brain-wide structure and account for NF1 imaging findings is unknown. Here we show that Nf1 gene inactivation in adult oligodendrocytes (Plp-Nf1fl/+ mice) results in a motor coordination deficit. Magnetic resonance imaging in awake mice showed that fractional …

Understanding The Intention To Use Telehealth Services In Underserved Hispanic Border Communities: Cross-Sectional Study, Suad Ghaddar, Kristina Vatcheva, Samantha G. Alvarado, Laryssa Mykyta

Health & Biomedical Sciences Faculty Publications and Presentations

Background: Despite the United States having one of the leading health care systems in the world, underserved minority communities face significant access challenges. These communities can benefit from telehealth innovations that promise to improve health care access and, consequently, health outcomes. However, little is known about the attitudes toward telehealth in these communities, an essential first step toward effective adoption and use.

Objective: The purpose of this study is to assess the factors that shape behavioral intention to use telehealth services in underserved Hispanic communities along the Texas-Mexico border and examine the role of electronic health (eHealth) literacy in telehealth …

Long Distance Gene Flow Facilitated By Bird-Dispersed Seeds In Wind-Pollinated Species: A Story Of Hybridization And Introgression Between Juniperus Ashei And J. Ovata Told By Nrdna And Cpdna, Robert P. Adams, Sam T. Johnson, Andrea E. Schwarzbach

Health & Biomedical Sciences Faculty Publications and Presentations

nrDNA and cpDNA were sequenced of J. ashei and J. ovata from populations throughout their ranges. No J. ashei populations were found to be pure in their nrDNA for every tree, however all J. ashei trees in every population contained only the pure J. ashei chloroplast type. Populations of J. ovata in trans-Pecos Texas were almost pure in both nrDNA and cp DNA. Several plants in the J. ashei range contained J. ovata-type nrDNA (White Cliffs, AR, 3/10); Ranger, TX (1/5); Waco, TX (1/12). Every J ashei population contained at least 1 plant with hybrid (heterozygous) nrDNA and 3 J. …

A Qualitative Analysis Of The Social And Cultural Contexts That Shape Screen Time Use In Latino Families Living On The U.S.-Mexico Border, Cristina S. Barroso, Andrew E. Springer, Christopher Ledingham, Steven H. Kelder

Health & Biomedical Sciences Faculty Publications and Presentations

Purpose: The purpose of this study was to understand how first generation Latino parents, whose primary language is Spanish and live in a colonia on the U.S.-Mexico border, use screen time in their homes.

Methods: A purposeful sampling approach was used to recruit eligible parents of pre-adolescents (ages 9–14) who were native Spanish speakers, and living on the U.S.-Mexico border. Three focus groups in Spanish (two with mothers and one with fathers) were conducted. Data were codified using a general inductive approach based on grounded theory. A consensus process was repeated until a final codebook was developed.

Results …

A Review Of Clinical Informatics Competencies In Nursing To Inform Best Practices In Education And Nurse Faculty Development, Tracia M. Forman, David A. Armor, Ava S. Miller

Health & Biomedical Sciences Faculty Publications and Presentations

AIM

The aim of this literature review was to determine the state of the science related to clinical informatics competencies of registered nurses and to determine best practices in educational strategies for both nursing students and faculty.

BACKGROUND

Continued emphasis on the provision of evidence-based patient care has implications for requisite informatics-focused competencies to be threaded throughout all levels of nursing educational programs.

METHOD

Whittemore and Knalf’s five-step integrative review process guided this research. An extensive search yielded 69 publications for critical appraisal.

RESULTS

Results suggest nursing educational programs do not adhere to standardized criteria for teaching nursing informatics competencies. …

Short Treatment With Antalarmin Alters Adrenal Gland Receptors In The Rat Model Of Endometriosis, Annelyn Torres-Reveron, Maahrose Rana, Varesh Gorabi, Leslie L. Rivera-Lopez, Caroline B. Appleyard

Health & Biomedical Sciences Faculty Publications and Presentations

Endometriosis is a chronic inflammatory disorder in which endometrial tissue is found outside the uterine cavity. Previous reports suggest that there is a dysregulation of the hypothalamic pituitary adrenal axis during the progression of endometriosis. Our previous report showed that a short-term treatment with antalarmin, a corticotrophin releasing hormone receptor type 1 (CRHR1) antagonist decreases the number and size of endometriotic vesicles in the auto-transplantation rat model of endometriosis. Our current goal was to examine the mRNA expression of intra-adrenal receptors to better understand the mechanisms of the hypothalamic pituitary adrenal (HPA) axis involvement in endometriosis. We used two groups …