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Roadside Exposure And Inflammation Biomarkers Among A Cohort Of Traffic Police In Kathmandu, Nepal, Kabindra M. Shakya, Richard E. Peltier, Yimin Zhang, Basu D. Pandey
Roadside Exposure And Inflammation Biomarkers Among A Cohort Of Traffic Police In Kathmandu, Nepal, Kabindra M. Shakya, Richard E. Peltier, Yimin Zhang, Basu D. Pandey
Environmental Health Sciences Faculty Publication Series
Air pollution is a major environmental problem in the Kathmandu Valley. Specifically, roadside and traffic-related air pollution exposure levels were found at very high levels exceeding Nepal air quality standards for daily PM2.5. In an exposure study involving traffic police officers, we collected 78 blood samples in a highly polluted spring season (16 February 2014–4 April 2014) and 63 blood samples in the less polluted summer season (20 July 2014–22 August 2014). Fourteen biomarkers, i.e., C-reactive protein (CRP), serum amyloid A (SAA), intracellular adhesion molecule (ICAM-1), vascular cell adhesion molecule (VCAM-1), interferon gamma (IFN-γ), interleukins (IL1-β, IL-2, IL-4, …