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Articles 1 - 4 of 4
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Personalized Medicine: The Use Of Biomarkers And Molecularly Targeted Therapies For Patient Care And Cancer Intervention, Wafa Asad, Emily Schmitt Lavin
Personalized Medicine: The Use Of Biomarkers And Molecularly Targeted Therapies For Patient Care And Cancer Intervention, Wafa Asad, Emily Schmitt Lavin
Mako: NSU Undergraduate Student Journal
Personalized medicine and targeted therapy have been emerging fields of study for the remediation and inhibition of cancer. Personalized medicine in the treatment of cancer involves using genetic, immune, and proteomic profiling to provide therapeutic options as well as prognostic background for every patient and their tumor’s genetic mutations. Targeted therapies allow researchers and medical personnel alike to determine the appropriate treatment for a patient based on the molecular basis and mechanistic actions of a cancerous tumor. The overall significance of this study was to express how these treatments use biomarkers to pinpoint the location, and severity of the cancer, …
The Interplay Of The Oral-Gut Microbiome With Chronic Inflammation In Rheumatoid Arthritis And Crohn's Disease, Anuradha Rampersaud
The Interplay Of The Oral-Gut Microbiome With Chronic Inflammation In Rheumatoid Arthritis And Crohn's Disease, Anuradha Rampersaud
Mako: NSU Undergraduate Student Journal
Abstract
Rheumatoid Arthritis (RA) and Crohn’s Disease (CD) are both chronic inflammatory diseases that share developmental and treatment similarities. RA’s symptoms include swelling, stiffness, and pain in synovial joints, corresponding with bone and cartilage destruction. CD’s symptoms include abdominal pain, bowel obstruction, bloating, diarrhea, and fever. The purpose of this literature review was to investigate the links between these two diseases and propose future treatment and prevention targets. Current treatment for RA and CD aims to suppress inflammation by targeting its mediators. However, this review noted that there should be greater focus on resolving inflammation. Both diseases are characterized by …
Ace2/Ang1-7 Mas Axis: The Counter-Regulator Of The Classical Renin Angiotensin System, Widelyne Dorsainval
Ace2/Ang1-7 Mas Axis: The Counter-Regulator Of The Classical Renin Angiotensin System, Widelyne Dorsainval
Mako: NSU Undergraduate Student Journal
To maintain homeostasis, the renin-angiotensin system (RAS) works to regulate the cardiovascular, renal, respiratory, and neurological systems of the body. However, there is evidence that abundant amounts of certain components of the RAS have detrimental effects and enhance disease. Recent studies have proved that there is a lesser known RAS which acts to counterbalance the classical RAS. To better understand their interaction, the effects of the alternate RAS against the classical RAS in the homeostatic systems of the body are researched and analyzed. The classical pathway employs these components: angiotensin converting enzyme (ACE), angiotensin II (AngII), and angiotensin II type …
Arranged Marriages: An Inappropriate Fabrication, Karika Sethi, Michael D. Reiter
Arranged Marriages: An Inappropriate Fabrication, Karika Sethi, Michael D. Reiter
Mako: NSU Undergraduate Student Journal
This paper explores what an inappropriate relationship is and the taxonomy scale used to evaluate different relationships, specifically, arranged marriages. Arranged marriage is a topic that is considered taboo depending on global location. It is more prevalent in Eastern nations such as India, China, Oriental countries, and the Middle East. However, Western influence plays a significant role on what is and is not acceptable, as societal norms differ from place to place. What is defined as normal by culture is what helps to define if a relationship is or is not viewed as inappropriate. This paper is designed to explore …