Open Access. Powered by Scholars. Published by Universities.®
- Keyword
-
- Animal behavior (1)
- Animal sexual behavior (1)
- Applied Physiology and Kinesiology (1)
- Beans (1)
- Biophysics (1)
-
- Center for Movement Disorders and Neurorestoration (1)
- Conformational dynamics (1)
- Conformational selection (1)
- Contraception (1)
- Data management (1)
- Enzyme I (1)
- Gd(III) complexes (1)
- Glycemic response (1)
- Horses (1)
- Isotopic labeling (1)
- Malaria (1)
- Mosquito (1)
- NMR (1)
- NMR spectroscopy (1)
- Neurology (1)
- Paramagnetic probe (1)
- Parasitism (1)
- Phosphoenolypruvate: sugar phosphotransferase system (1)
- Phosphorylation enzymes (1)
- Plasmodium (1)
- Protein hydration (1)
- Protein structure (1)
- Protein surface assessibility (1)
- Relaxation dispersion (1)
- Reproductive physiology (1)
Articles 1 - 15 of 15
Full-Text Articles in Entire DC Network
Regulation Of Anti-Plasmodium Immunity By A Litaf-Like Transcription Factor In The Malaria Vector Anopheles Gambiae, Ryan C. Smith, Abraham G. Eappen, Andrea J. Radtke, Marcelo Jacobs-Lorena
Regulation Of Anti-Plasmodium Immunity By A Litaf-Like Transcription Factor In The Malaria Vector Anopheles Gambiae, Ryan C. Smith, Abraham G. Eappen, Andrea J. Radtke, Marcelo Jacobs-Lorena
Ryan C. Smith
The mosquito is the obligate vector for malaria transmission. To complete its development within the mosquito, the malaria parasite Plasmodium must overcome the protective action of the mosquito innate immune system. Here we report on the involvement of the Anopheles gambiae orthologue of a conserved component of the vertebrate immune system, LPS-induced TNFα transcription factor (LITAF), and its role in mosquito anti-Plasmodium immunity. An. gambiae LITAF-like 3 (LL3) expression is up-regulated in response to midgut invasion by both rodent and human malaria parasites. Silencing of LL3 expression greatly increases parasite survival, indicating that LL3 is part of an anti-Plasmodium defense …
Create Change Through Knowledge About Traumatic Brain Injury (Tbi), Debra M. Sellers
Create Change Through Knowledge About Traumatic Brain Injury (Tbi), Debra M. Sellers
Debra M. Sellers
Fact sheet about traumatic brain injury. Describes types of injuries, risk groups, physical, cognitive, emotional, and behavioral changes. Consequences affect relationships, daily living and work. Communities and individuals can help survivors adjust.
Create A Supportive Community For People Who Experience Traumatic Brain Injury (Tbi), Debra M. Sellers
Create A Supportive Community For People Who Experience Traumatic Brain Injury (Tbi), Debra M. Sellers
Debra M. Sellers
Community tip sheet to help people with traumatic brain injuries.
Create Positive Differences For People Who Experience Traumatic Brain Injuries, Debra M. Sellers
Create Positive Differences For People Who Experience Traumatic Brain Injuries, Debra M. Sellers
Debra M. Sellers
Individual tip sheet to help those who work with people with traumatic brain injuries.
Bean And Rice Meals Reduce Postprandial Glycemic Response In Adults With Type 2 Diabetes: A Cross-Over Study, Sharon V. Thompson, Donna M. Winham, Andrea M. Hutchins
Bean And Rice Meals Reduce Postprandial Glycemic Response In Adults With Type 2 Diabetes: A Cross-Over Study, Sharon V. Thompson, Donna M. Winham, Andrea M. Hutchins
Donna Winham
Background: Around the world, beans and rice are commonly consumed together as a meal. With type 2 diabetes increasing, the effect of this traditional diet pattern on glycemic response has not been studied fully. Methods: We evaluated the glycemic response of bean and rice traditional meals compared to rice alone in adults with type 2 diabetes. Seventeen men and women with type 2 diabetes controlled by metformin (n = 14) or diet/exercise (n=3) aged 35–70 years participated in the randomized 4 × 4 crossover trial. The white long grain rice control, pinto beans/rice, black beans/rice, red kidney beans/rice test meals, …
Traumatic Brain Injury: Exploring The Role Of Cooperative Extension In Kansas Communities, Debra M. Sellers, Jane Mertz Garcia
Traumatic Brain Injury: Exploring The Role Of Cooperative Extension In Kansas Communities, Debra M. Sellers, Jane Mertz Garcia
Debra M. Sellers
TBIoptions helps survivors of traumatic brain injury and their families identify, locate, and contact helpful organizations in their local communities to promote successful living. This article discusses the role of county agents in the program and the support offered by community partners. Results of pre- and post-surveys for both groups are reported. The research provides information regarding changes in knowledge and noteworthy outcomes for participating agents and community partners. Through engagement in the issue of traumatic brain injury, Extension is better positioned to meet the needs of survivors, family members, and caregivers within Kansas.
Living Wills In Kansas, Debra M. Sellers, Erin J. Dittman
Living Wills In Kansas, Debra M. Sellers, Erin J. Dittman
Debra M. Sellers
A living will allows you to record in writing, what type of care you want at the end of your life, if you have a terminal illness.
Durable Power Of Attorney For Health Care In Kansas, Debra M. Sellers, Erin J. Dittman
Durable Power Of Attorney For Health Care In Kansas, Debra M. Sellers, Erin J. Dittman
Debra M. Sellers
Name a person authorized to make your health care decisions for you, when you are not capable of making decisions for yourself, with a Durable Power of Attorney.
Advanced Directives In Kansas, Debra M. Sellers, Erin J. Dittman
Advanced Directives In Kansas, Debra M. Sellers, Erin J. Dittman
Debra M. Sellers
Advance directives are documents to state how you want to be cared for at the end of your life: durable power of attorney for health care and living will.
What Is The Risk For Metabolic Syndrome In Police Officers?, Warren D. Franke
What Is The Risk For Metabolic Syndrome In Police Officers?, Warren D. Franke
Warren D Franke
The report by Jayakrishnan and colleagues in this Journal is noteworthy since it provides an assessment of the presence of the metabolic syndrome and related cardiovascular risk factors in one of the largest, if not the largest, cohort of police officers to date. Two aspects of this research especially warrant comment.
Quantitative Normative Gait Data In A Large Cohort Of Ambulatory Persons With Parkinson’S Disease, Chris J. Hass, Paul Malczak, Joe Nocera, Elizabeth L. Stegemoller, Aparna Wagle Shukala, Irene Malaty, Charles E. Jacobson Iv, Michael S. Okun, Nick Mcfarland
Quantitative Normative Gait Data In A Large Cohort Of Ambulatory Persons With Parkinson’S Disease, Chris J. Hass, Paul Malczak, Joe Nocera, Elizabeth L. Stegemoller, Aparna Wagle Shukala, Irene Malaty, Charles E. Jacobson Iv, Michael S. Okun, Nick Mcfarland
Elizabeth L. Stegemoller
Background: Gait performance is widely evaluated to assess health status in older adult populations. While several investigators have presented normative values for spatiotemporal gait parameters drawn from older adult populations, the literature has been void of large-scale cohort studies, which are needed in order to provide quantitative, normative gait data in persons with Parkinson’s disease. The aim of this investigation was to provide reference values for clinically important gait characteristics in a large sample of ambulatory persons with Parkinson’s disease to aid both clinicians and researchers in their evaluations and treatments of gait impairment. Methodology/Principal Findings: Gait performance was collected …
Does Immunocontraception In Feral Horses (Equus Caballus) Extend Reproductive Cycling Beyond The Normal Breeding Season?, Cassandra M.V. Nuñez, James S. Adelman, Daniel I. Rubenstein
Does Immunocontraception In Feral Horses (Equus Caballus) Extend Reproductive Cycling Beyond The Normal Breeding Season?, Cassandra M.V. Nuñez, James S. Adelman, Daniel I. Rubenstein
Cassandra M.V. Nuñez
Although the physiological effects of immunocontraceptive treatment with porcine zona pellucida (PZP) have been well studied, little is known about PZP’s effects on the scheduling of reproductive cycling. Recent behavioral research has suggested that recipients of PZP extend the receptive breeding period into what is normally the non-breeding season. To determine if this is the case, we compiled foaling data from wild horses (Equus caballus) living on Shackleford Banks, North Carolina for 4 years pre- and 8 years post-contraception management with PZP (pre-contraception, n = 65 births from 45 mares; post-contraception, n = 97 births from 46 mares). Gestation lasts …
The Use Of A Ditopic Gd(Iii) Paramagnetic Probe For Investigating Α-Bungarotoxin Surface Accessibility, Andrea Bernini, Ottavia Spiga, Vincenzo Venditti, Filippo Prischi, Mauro Botta, Gianluca Croce, Angela Pui-Ling Tong, Wing-Talk Wong, Neri Niccolai
The Use Of A Ditopic Gd(Iii) Paramagnetic Probe For Investigating Α-Bungarotoxin Surface Accessibility, Andrea Bernini, Ottavia Spiga, Vincenzo Venditti, Filippo Prischi, Mauro Botta, Gianluca Croce, Angela Pui-Ling Tong, Wing-Talk Wong, Neri Niccolai
Vincenzo Venditti
Protein surface accessibility is a critical parameter which drives all intermolecular interaction processes. In this respect a big deal of information has been derived by analyzing paramagnetic perturbation profiles obtained from NMR protein spectra, particularly in the case that the effects due to different soluble paramagnets can be compared. Here Gd2L7, a neutral ditopic paramagnetic NMR probe, has been characterized in terms of structure and relaxivity and its paramagnetic perturbations on α-bungarotoxin CαH signals in 1H–13C HSQC (heteronuclear single quantum coherence) spectra have been analyzed. Then, these signal attenuations have been compared with the ones previously obtained in the presence …
An Efficient Protocol For Incorporation Of An Unnatural Amino Acid In Perdeuterated Recombinant Proteins Using Glucose-Based Media, Vincenzo Venditti, Nicolas L. Fawzi, G. Marius Clore
An Efficient Protocol For Incorporation Of An Unnatural Amino Acid In Perdeuterated Recombinant Proteins Using Glucose-Based Media, Vincenzo Venditti, Nicolas L. Fawzi, G. Marius Clore
Vincenzo Venditti
The in vivo incorporation of unnatural amino acids into proteins is a well-established technique requiring an orthogonal tRNA/aminoacyl-tRNA synthetase pair specific for the unnatural amino acid that is incorporated at a position encoded by a TAG amber codon. Although this technology provides unique opportunities to engineer protein structures, poor protein yields are usually obtained in deuterated media, hampering its application in the protein NMR field. Here, we describe a novel protocol for incorporating unnatural amino acids into fully deuterated proteins using glucose-based media (which are relevant to the production, for example, of amino acid-specific methyl-labeled proteins used in the study …
Conformational Selection And Substrate Binding Regulate The Monomer/Dimer Equilibrium Of The C-Terminal Domain Of Escherichia Coli Enzyme I, Vincenzo Venditti, G. Marius Clore
Conformational Selection And Substrate Binding Regulate The Monomer/Dimer Equilibrium Of The C-Terminal Domain Of Escherichia Coli Enzyme I, Vincenzo Venditti, G. Marius Clore
Vincenzo Venditti
The bacterial phosphotransferase system (PTS) is a signal transduction pathway that couples phosphoryl transfer to active sugar transport across the cell membrane. The PTS is initiated by the binding of phosphoenolpyruvate (PEP) to the C-terminal domain (EIC) of enzyme I (EI), a highly conserved protein that is common to all sugar branches of the PTS. EIC exists in a dynamic monomer/dimer equilibrium that is modulated by ligand binding and is thought to regulate the overall PTS. Isolation of EIC has proven challenging, and conformational dynamics within the EIC domain during the catalytic cycle are still largely unknown. Here, we present …