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Articles 1 - 7 of 7
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The Influence Of Time Perspective On Physical Activity Intentions And Behaviors Among Adolescents Residing In Central Appalachia., Tauna Gulley
Electronic Theses and Dissertations
Obesity and inactivity are prevalent among central Appalachian adolescents. Appalachian residents have been labeled "fatalistic," a time perspective unsupportive of health-promoting behaviors such as regular participation in physical activity. The theory of planned behavior has been used extensively to explain the physical activity behaviors of adolescents. Constructs within the theory of planned behavior include attitudes toward the behavior, subjective norms, perceived behavioral control, and intention to perform the behavior. The purpose of this study was to determine the time perspective of central Appalachian adolescents and examine the relationship between time perspective and the constructs within the theory of planned behavior. …
Genome-Wide Association Analysis Of Major Depressive Disorder And Its Related Phenotypes., Nagesh Ramarao Aragam
Genome-Wide Association Analysis Of Major Depressive Disorder And Its Related Phenotypes., Nagesh Ramarao Aragam
Electronic Theses and Dissertations
Major Depressive Disorder (MDD) is a complex and chronic disease that ranks fourth as cause of disability worldwide. Thirteen to 14 million adults in the U.S. are believed to have MDD and an estimated 75% attempt suicide making MDD a major public health problem. Recently several genome-wide association (GWA) studies of MDD have been reported; however, few GWA studies focus on the analysis for MDD related phenotypes such as neuroticism and age at onset of MDD. The purpose of this study is to determine risk factors for MDD, identify genome-wide genetic variants affecting neuroticism and age at onset as quantitative …
Effect Of Gender On The Association Of Single-Nucleotide Polymorphisms With Bipolar Disorder, Jerald Eric Mullersman
Effect Of Gender On The Association Of Single-Nucleotide Polymorphisms With Bipolar Disorder, Jerald Eric Mullersman
Electronic Theses and Dissertations
Bipolar disorder is a relatively common form of mental illness that depends strongly on genetic inheritance for expression. The author of this study has sought to evaluate whether the gender of subjects influences which genetic variants are associated with the disease. A portion of the cases from a previously published study were analyzed using PLINK software and the association of single-nucleotide polymorphisms was evaluated separately for all cases, for female subjects alone, and for male subjects alone. The results obtained for male subjects alone reached higher levels of statistical significance than when both genders were evaluated together or when female …
Traditional Story As A Tool In Substance Abuse Prevention And Treatment., Claiborne Beth Ohlsson
Traditional Story As A Tool In Substance Abuse Prevention And Treatment., Claiborne Beth Ohlsson
Electronic Theses and Dissertations
This qualitative study examined the viability of traditional stories in substance abuse treatment. The subjects for this study were young women ages 18-30 who were in substance abuse treatment in a small, rural, health department. During the 4-week study, 4 traditional stories were used in group sessions that gave the women a common reference point and a common language to frame discussions. Using story in the IOP sessions helped to create a safe, supportive environment as well as creating an opening for discussions about trauma and abuse, and other significant issues. Principles of 12 Step Recovery were woven into the …
Temperamental Profiles Of Children With Communication Impairment., Whitney Charlena Lau
Temperamental Profiles Of Children With Communication Impairment., Whitney Charlena Lau
Electronic Theses and Dissertations
The temperament literature available that involves children with communication impairments is limited but promising. The purpose of this study was to investigate the temperamental profiles of children with autism spectrum disorders, primary language impairments, phonological/articulation impairments, and combined phonological and language impairments. Participants included 38 children who attended the East Tennessee State University Speech-Language-Hearing Clinic at the time of the study or in the past 10 years. Parents of eligible participants were asked to complete demographic and temperament questionnaires about their children. Results indicated that the temperamental profiles of children with communication impairments differed significantly from typically developing children in …
Biopharmaceutic And Pharmacokinetic Studies Of Sucrose Acetate Isobutyrate As An Excipient For Oral Drug Delivery., Martin Ray Tant
Biopharmaceutic And Pharmacokinetic Studies Of Sucrose Acetate Isobutyrate As An Excipient For Oral Drug Delivery., Martin Ray Tant
Electronic Theses and Dissertations
Sucrose acetate isobutyrate (SAIB), a randomly substituted sucrose approximating sucrose diacetate hexaisobutyrate, is produced by Eastman Chemical Company for a variety of applications. SAIB is widely used in the food industry as a weighting agent to disperse flavoring oils in primarily citrus-based soft drink beverages. Additionally, SAIB is currently being marketed by another company as a parenteral drug delivery system. The studies reported here focused on investigating SAIB as an excipient, or delivery vehicle, for use in oral delivery of several drugs, including ibuprofen, saquinavir, and clarithromycin. Dissolution experiments were conducted using both ibuprofen and caffeine, and results suggest that …
The Lived Experience Of Mothers Bereaved By The Suicide Death Of A Child., Cynthia Walker Lynn
The Lived Experience Of Mothers Bereaved By The Suicide Death Of A Child., Cynthia Walker Lynn
Electronic Theses and Dissertations
Suicide has existed throughout recorded history. It is a phenomenon that has been both culturally and morally defined across time and civilizations. It is estimated that over 34,000 Americans deliberately take their own lives annually. Moreover, according to some experts, between 6 and 28 individuals are directly affected by each completed suicide. These individuals are referred to as suicide survivors. The consequences for suicide survivors are multidimensional in part because relationships to the deceased play a vital role in bereavement. Previous research studies in the areas of suicidology and bereavement have failed to explore the experience of mothers bereaved …