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Comparison Of Equations For Estimating Glomerular Filtration Rate In Screening For Chronic Kidney Disease In Asymptomatic Black Africans: A Cross Sectional Study, Geoffrey Omuse, Daniel Maina, Jane Mwangi, Caroline Wambua, Alice Kiyua, Elizabeth Kagotho, Angela Amayo, Peter Ojwang, Rajiv Erasmus
Comparison Of Equations For Estimating Glomerular Filtration Rate In Screening For Chronic Kidney Disease In Asymptomatic Black Africans: A Cross Sectional Study, Geoffrey Omuse, Daniel Maina, Jane Mwangi, Caroline Wambua, Alice Kiyua, Elizabeth Kagotho, Angela Amayo, Peter Ojwang, Rajiv Erasmus
Pathology, East Africa
Background: Several equations have been developed to estimate glomerular filtration rate (eGFR). The common equations used were derived from populations predominantly comprised of Caucasians with chronic kidney disease (CKD). Some of the equations provide a correction factor for African-Americans due to their relatively increased muscle mass and this has been extrapolated to black Africans. Studies carried out in Africa in patients with CKD suggest that using this correction factor for the black African race may not be appropriate. However, these studies were not carried out in healthy individuals and as such the extrapolation of the findings to an asymptomatic black …
Evaluation Of 'Ckd-Epi Pakistan' Equation For Estimated Glomerular Filtration Rate (Egfr): A Comparison Of Egfr Prediction Equations In Pakistani Population, Sibtain Ahmed, Lena Jafri, Ayesha Habib Khan
Evaluation Of 'Ckd-Epi Pakistan' Equation For Estimated Glomerular Filtration Rate (Egfr): A Comparison Of Egfr Prediction Equations In Pakistani Population, Sibtain Ahmed, Lena Jafri, Ayesha Habib Khan
Department of Pathology and Laboratory Medicine
Objective: To evaluate the results of 24-hour urinary creatinine clearance (CrCl) with estimated glomerular filtration rate (eGFR) using the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI), CKD-EPI Pakistan (CKD-EPI Pak), Cockcroft Gault (CG) and 4-variable Modification of Diet in Renal Disease (MDRD) equations.
Study Design: Descriptive, cross-sectional study.
Place and Duration of Study: Section of Clinical Chemistry, Department of Pathology and Laboratory Medicine, The Aga Khan University, Karachi, from June to October 2013. Methodology: Laboratory data of subjects ≥18 years ordering 24-hour urinary CrCl from June to October 2013 was retrieved. Statistical comparison of eGFR using CKD-EPI, CKD-EPI Pak, CG and …