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Case Report: Nocturnal Low-Frequency Stimulation Of The Centromedian Thalamic Nucleus Improves Sleep Quality And Seizure Control, Surya Suresh, Ganne Chaitanya, Ajay Deep Kachhvah, Vladimir Vashin, Manojkumar Saranathan, Sandipan Pati
Case Report: Nocturnal Low-Frequency Stimulation Of The Centromedian Thalamic Nucleus Improves Sleep Quality And Seizure Control, Surya Suresh, Ganne Chaitanya, Ajay Deep Kachhvah, Vladimir Vashin, Manojkumar Saranathan, Sandipan Pati
Journal Articles
Sleep disturbances and drug-resistant seizures significantly impact people with idiopathic generalized epilepsy (IGE). Thalamic deep brain stimulation (DBS) offers potential treatment, but its effect on sleep and seizure control needs clarification. In this study, we combined wearable sleep monitoring with electroencephalogram (EEG) confirmation to investigate the impact of nocturnal centromedian nucleus (CM) DBS parameters in a patient with drug-resistant IGE. We found that high-frequency (125 Hz) CM stimulation during sleep severely disrupted sleep macro architecture and exacerbated seizures. Conversely, switching to low-frequency (10 Hz) stimulation enhanced both sleep quality and seizure control. This study underscores the critical need to personalize …
Sleep Spindles Promote The Restructuring Of Memory Representations In Ventromedial Prefrontal Cortex Through Enhanced Hippocampal-Cortical Functional Connectivity, E. Cowan, A. Liu, S. Henin, S. Kothare, O. Devinsky, L. Davachi
Sleep Spindles Promote The Restructuring Of Memory Representations In Ventromedial Prefrontal Cortex Through Enhanced Hippocampal-Cortical Functional Connectivity, E. Cowan, A. Liu, S. Henin, S. Kothare, O. Devinsky, L. Davachi
Journal Articles
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