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Medical Humanities

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University of Alabama at Birmingham

Theses/Dissertations

2022

An ectopic fat depot associated with cardiometabolic disease. We found RSF to be inversely associated with diastolic blood pressure in AA individuals. Additionally

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Health Disparities In Cardiometabolic Risk Among African American And European American Adults, Catharine A. Couch Jan 2022

Health Disparities In Cardiometabolic Risk Among African American And European American Adults, Catharine A. Couch

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African American (AA) individuals are disproportionately burdened by cardiometabolic disease, including type 2 diabetes (T2D) and cardiovascular disease (CVD), and associated risk factors. The objective of this dissertation research was to investigate pathophysiological and lifestyle contributors to racial disparities in cardiometabolic disease including beta-cell dysfunction, ectopic fat, the natriuretic peptide system, and diet. These first three risk factors, beta-cell dysfunction, ectopic fat, and the natriuretic peptide system, were explored in a cross-sectional study of young AA and European American (EA) adults. The fourth risk factor, diet, was explored in a large, national cohort of black and white adults. First, we …