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Development Of High-Speed Photoacoustic Imaging Technology And Its Applications In Biomedical Research, Yun He Dec 2019

Development Of High-Speed Photoacoustic Imaging Technology And Its Applications In Biomedical Research, Yun He

McKelvey School of Engineering Theses & Dissertations

Photoacoustic (PA) tomography (PAT) is a novel imaging modality that combines the fine lateral resolution from optical imaging and the deep penetration from ultrasonic imaging, and provides rich optical-absorption–based images. PAT has been widely used in extracting structural and functional information from both ex vivo tissue samples to in vivo animals and humans with different length scales by imaging various endogenous and exogenous contrasts at the ultraviolet to infrared spectrum. For example, hemoglobin in red blood cells is of particular interest in PAT since it is one of the dominant absorbers in tissue at the visible wavelength.The main focus of …


Asme Design Challenge: The Jenga Stacker, Zachary Lin, Alex Chernauskas, Mitch Dorsey, Alex Remmers Dec 2019

Asme Design Challenge: The Jenga Stacker, Zachary Lin, Alex Chernauskas, Mitch Dorsey, Alex Remmers

Mechanical Engineering Design Project Class

The 2020 ASME Design Challenge requires teams to build a compact engineering system capable of manufacturing a tower made exclusively from standard-sized sheets of paper. The validation of the design will include testing for manufacturing speed, height of tower, and ability to support a load. Our senior design project focuses on the stacking mechanism and is designed to stack a 4 in x 4 in tower out of prepared 4 in x 1.5 in x 1.75 in paper boxes from the ground up.


Improved Greens Harvester, Sharon Park, Khalil Clark, Millyn Brieschke Dec 2019

Improved Greens Harvester, Sharon Park, Khalil Clark, Millyn Brieschke

Mechanical Engineering Design Project Class

This paper attempts to provide a prototype of the improved greens harvester. Some inconveniences of the users, including not able to cut greens at a constant length, greens getting clogged in between the brush and the basket, and the need to empty the basket a lot of times. This paper describes problem understanding, concept generation, concept selection, concept embodiment, working prototype, and design refinement. Through these analyses and processes, an improved greens harvester solving the inconveniences is designed. The improved greens harvester has a higher greens harvester with wheels that makes using the harvester less troublesome. Band saw is stuck …


Group A: Asme Student Design Challenge, Dakshi Jindal, Ashley Perry, Ben Liao Dec 2019

Group A: Asme Student Design Challenge, Dakshi Jindal, Ashley Perry, Ben Liao

Mechanical Engineering Design Project Class

This year's student design competition is termed "Building to the Sky." Student teams are required to build a compact engineering system capable of manufacturing a tower made of only standard-sized sheets of paper.


Group E: Improved Greens Harvester, Paige Grittner, Paul Harding, Ned Curran, Jennifer Mata Dec 2019

Group E: Improved Greens Harvester, Paige Grittner, Paul Harding, Ned Curran, Jennifer Mata

Mechanical Engineering Design Project Class

The Improved Greens Harvester is a project designing an improved machine that will be used to harvest crops by our client, EarthDance Organic Farm School in Ferguson, MO. The goal of our design was to provide a simple, easy-to-use, and easyto-fix machine that would cut and collect baby green leaves as the user walks along the plant bed. We first sought to address issue with the client’s current machine including low cutting accuracy, strain on the user’s body, frequent jamming, and low efficiency. Our initial design was a cart design that included: an oscillating blade for cutting, a rotating rope-shaft …


Group S- Arliss Project, Preston Bailey, Zach Stelwagon, Cal Reynolds, James Hardy Dec 2019

Group S- Arliss Project, Preston Bailey, Zach Stelwagon, Cal Reynolds, James Hardy

Mechanical Engineering Design Project Class

Our project was the ARLISS competition project, more specifically the second part of the project where the vehicle must survive a drop and drive to a known location over rough desert terrain. We interviewed our professor, Dr. Potter, who had previous experience with the project to understand what was required in our design. The project started with creating concept ideas and deciding on one, which initially was an airplane to avoid designing a landing mechanism and having to drive over rough terrain. However, this design proved to have too many flaws and was scrapped. The new design was a small …


Longitudinal Acoustic Traps: Design, Fabrication, And Evaluation For Biological Applications, Michael Moore Binkley Dec 2019

Longitudinal Acoustic Traps: Design, Fabrication, And Evaluation For Biological Applications, Michael Moore Binkley

McKelvey School of Engineering Theses & Dissertations

Acoustofluidics combine ultrasonic actuation with small-volume microfluidic channels to enable precise, contactless object manipulation for a range of applications from serial chemical processing to blood component separation and single-cell analysis. Micron- to millimeter-scale vibrational waves generate reproducible pressure fields within the microfluidic channels and chambers. By exploiting the material property mismatch between a particle (polymeric and silica beads, cells, etc.) and a suspending fluid, the acoustic radiation force is used to move particles toward regions of low (nodes) or high pressure (antinodes). An understanding of these field-particle interactions is applied to design and implement complicated channel architectures for preferential segregation …


3d Chocolate Printer Bed Design, Dean Oken, Jacob Margolin, Ben Hartmann, Sam Grossman Dec 2019

3d Chocolate Printer Bed Design, Dean Oken, Jacob Margolin, Ben Hartmann, Sam Grossman

Mechanical Engineering Design Project Class

The client wished for a device to gain the interest of young undergraduate students into basic thermal science and fluid dynamics concepts. A 3D printer bed was created from concept to prototype design and paired with chocolate dropper teams to complete the project and accomplish the client's goals.


Enhanced Heat Transfer Performance By Shape Optimization Of A Non-Axisymmetric Droplet Evaporating On A Heated Micropillar, Haotian Wu Dec 2019

Enhanced Heat Transfer Performance By Shape Optimization Of A Non-Axisymmetric Droplet Evaporating On A Heated Micropillar, Haotian Wu

McKelvey School of Engineering Theses & Dissertations

Abstract

Enhanced Heat Transfer Performance by Shape Optimization of a Non-axisymmetric Droplet Evaporating on a Heated Micropillar

By

Haotian Wu

Department of Mechanical Engineering and Materials Science

Washington University in St. Louis, 2019

Research Advisor: Professor Damena Agonafer

The stacked multilayer 3D IC structure used in next generation high-powered electronics poses great challenges in dissipating their large heat flux, which causes extreme difficulties for traditional cooling technologies. In response, more advanced two-phase liquid cooling technologies, such as droplet evaporation, which utilizes the latent heat of vaporization to remove excessive heat, have been widely investigated. Compared to traditional single-phase cooling techniques, …


Mems 411 Group L (Fall 2019) - Speedy Seeder Final Report, Michael Morrow, Christopher Nelson, Ross Frame Dec 2019

Mems 411 Group L (Fall 2019) - Speedy Seeder Final Report, Michael Morrow, Christopher Nelson, Ross Frame

Mechanical Engineering Design Project Class

The Speedy Seeder or ”SS” is a device designed to decrease the time it takes to fill one seed plot by hand to roughly sixteen percent of the time. The customer of the SS is EarthDance Organic Farms School. EarthDance fills a large number of plots each year by placing a seed in every single compartment which come in three sizes: 32, 72, and 128 compartments per plot. Filling a single plot by hand can take roughly 8 minutes. The SS makes filling a plot much easier and faster, allowing a single plot to be filled in under 75 seconds. …


T-Shirt Strip Dispenser, Maxwell Dimgba, Syeda Mohsin, Sabrina Nguyen Dec 2019

T-Shirt Strip Dispenser, Maxwell Dimgba, Syeda Mohsin, Sabrina Nguyen

Mechanical Engineering Design Project Class

There is a massive amount of waste around the textile industry. New garments are constantly being made and old garments are consistently finding themselves in landfills. This project aims to cut down on this waste. Mary Susan RuppertStroescu of the Sam Fox School at Washington University in St. Louis has developed a process to turn old garments into new ones in a practice known as up-cycling. By cutting old garments into half-inch strips, laying and adhering them flat on a sheet of dissolvable paper, and sewing over them in interesting patterns she is able to create extraordinary new designs. This …


Group M: Arliss Canister Vehicle, Greyson Bourgeois, Eleanor Macklin, Romail Dawani, Rachel Sample Dec 2019

Group M: Arliss Canister Vehicle, Greyson Bourgeois, Eleanor Macklin, Romail Dawani, Rachel Sample

Mechanical Engineering Design Project Class

This project is a dicycle designed for the ARLISS Canister Competition. In this competition, the device is loaded into a rocket which is then launched to about 12000 ft before releasing the device. Then it must safely land and autonomously navigate to a predetermined GPS location on the ground. Due to the fact that this is a mechanical engineering design project and the time restrictions of this class, we focused on the physical aspect of the project, such as building a device that can survive the launch and landing and traverse several kilometers through the desert, forgoing the autonomous navigation …


Violin Bow-Hand Prosthetic, Jonathan Smith, Jonathon Azziz, Shawn Pavey Dec 2019

Violin Bow-Hand Prosthetic, Jonathan Smith, Jonathon Azziz, Shawn Pavey

Mechanical Engineering Design Project Class

The violin bow hand prosthetic was designed for a young violin player seeking to upgrade the functionality of his current violin prosthetic device. His current device is rigid, forcing him to play mostly with his shoulder. Since the strength of his wrist was unknown, we designed a prosthetic with enough brace flexibility to enable the user to control the bow motion with his own wrist. We also added an axis of rotation and spring mechanism to supplement this motion and provide him the equivalence of fine finger adjustments. The full design process of the prosthetic is documented in this report, …


Violin Bow-Hand Prosthetic, Ron Hayes Jr, Kc Cook, Romario Lobban, Muriel Drexler Dec 2019

Violin Bow-Hand Prosthetic, Ron Hayes Jr, Kc Cook, Romario Lobban, Muriel Drexler

Mechanical Engineering Design Project Class

The violin bow-hand prosthetic aims to mimic the natural hold and motion of a violinist’s bow-hand. The prosthetic is for a violinist who is missing the majority of their hand, but still has full range of motion in the wrist. Focusing on maintaining a natural playing style greatly influenced the design of the device to be user safe, durable, comfortable, easy to use, inexpensive, and practical. Many of these features were achieved by using 3D printed plastic and foam composites. These materials were selected based on strength and deflection analyses of 3-D simulations performed in SolidWorks and the ease of …


Group N: Fluid Flow Testing Apparatus, Jonathan Fleming, Braden Kerr, Abel Soloman Dec 2019

Group N: Fluid Flow Testing Apparatus, Jonathan Fleming, Braden Kerr, Abel Soloman

Mechanical Engineering Design Project Class

A fluid flow testing apparatus was needed to accurately test valves relative to the conditions seen in the factory of a local St. Louis brewery. After concept generation, a rotating track that toggled the valve between open and closed was decided on by the team. Construction of an initial prototype was done over 3 weeks with a total budget of 400 USD. The initial prototype satisfied almost all of the performance goals: capable of cycling 200 times without intervention, 1 paper-towel of leakage at most, and upper reservoir level consistency within 10 percent. To improve the initial prototype, the team …


Lupd - Leisure Underwater Propulsion Device, James Abraham, Tanner Nordell, Holden Schmidt, Noah Trimark Dec 2019

Lupd - Leisure Underwater Propulsion Device, James Abraham, Tanner Nordell, Holden Schmidt, Noah Trimark

Mechanical Engineering Design Project Class

The main objective of this Design Project was to create a hands-free, wearable underwater propulsion device. The target consumer is leisure divers, so managing cost was important. Current products on the market do not allow divers to be hands-free while diving and are very expensive. The design process began with an interview with Josh An, a Masters Degree candidate at Washington University in St. Louis. Josh is an avid diver and wanted to see if it was possible to develop a cheap underwater jet pack for leisure diving. After multiple design concepts and mock up prototypes, our team decided on …


Sweet Spot Demonstration, Andrew Amend, Mitchell Smith, Ian Fish, Curtis Hoffman Dec 2019

Sweet Spot Demonstration, Andrew Amend, Mitchell Smith, Ian Fish, Curtis Hoffman

Mechanical Engineering Design Project Class

Our goal was to design and build an exhibit for the St. Louis Science Center to serve as a teaching tool to help explain the unintuitive concept of a baseball bat’s sweet spot to a typical children museum’s visitor, a 5th grade student, in an interesting and visually pleasing way. The sweet spot of the bat is colloquially known as the place that makes the best contact with the ball, and it is determined by a combination of the center of percussion and location of vibrational nodes. We focused on showing how the location of bat-ball impact affects the vibration …


Sweet Spot Demonstration, Keval Amin, Beau Allen, Kieran Lenssen, Ricardo Del Olmo Parrado Dec 2019

Sweet Spot Demonstration, Keval Amin, Beau Allen, Kieran Lenssen, Ricardo Del Olmo Parrado

Mechanical Engineering Design Project Class

The purpose of this project was to create a sweet spot exhibit for the St. Louis Science Center to demonstrate the basic dynamic and vibrational theory behind the game of baseball. This demonstration focuses on the dynamics of batting and the effects that induced bat vibrations have on the energy transfer from the bat to the ball. Through this demonstration, the vibrational nodes within a baseball bat can be measured based on the ball’s contact with the ”sweet spot,” or the area on the barrel of the bat that induces the least amount of bat vibration. The project went through …


Automated Whiteboard Eraser, Trent Houpt, Tyler Polasek, Kenny Huang, Rocky Luo Dec 2019

Automated Whiteboard Eraser, Trent Houpt, Tyler Polasek, Kenny Huang, Rocky Luo

Mechanical Engineering Design Project Class

The Automated Whiteboard Eraser is a product designed to erase whiteboards with the touch of a button. With this product students and teachers will be able to save time and energy as they can continue to work without having to stop and erase. From our research others have attempted to construct similar products. We intend to improve these thoughts and designs in order to build a better and more efficient product.


Jet Beluga: Diver Propulsion Wearable, Jacob Graham, Bernardo Amaral Neves, Ethan Genter Dec 2019

Jet Beluga: Diver Propulsion Wearable, Jacob Graham, Bernardo Amaral Neves, Ethan Genter

Mechanical Engineering Design Project Class

Scuba diving is a physically and mentally challenging task performed in both recreational and professional settings. Recreational divers seek to experience the marine world for extended periods of time without buoyant resistance. Rescue divers, military personnel, and underwater construction workers train to execute complicated tasks in a limited time period. Diver propulsion vehicles can improve the quality of recreational diving as well as the effectiveness of diving as performed in professional settings. The following report describes the design and motivations for a wearable diver propulsion device that provides the benefits of increased speed and mobility while limiting the amount of …


Violin Prosthetic, Justin Kransdorf, Julia Rifkin, Hayden Reynolds, Payal Hukeri Dec 2019

Violin Prosthetic, Justin Kransdorf, Julia Rifkin, Hayden Reynolds, Payal Hukeri

Mechanical Engineering Design Project Class

Sam, an 11-year-old violin player was born without fingers or a thumb on his right hand. In order to learn the basics of violin, he currently uses a custom made prosthetic that allows him to hold a violin bow. However, his current prosthetic does not allow for the bow angle to change relative to his wrist, and thus, he cannot perform many techniques that are important to him furthering his violin skills. Specifically, his prosthetic allows Sam to use only a small percentage of the bow. For this project, a prosthetic was designed for Sam with the goal being to …


Ice Cream Dispensing Machine, Katie Bahnck, Rachel Lockwood, Marie White, Simone Raeth Dec 2019

Ice Cream Dispensing Machine, Katie Bahnck, Rachel Lockwood, Marie White, Simone Raeth

Mechanical Engineering Design Project Class

Each August, Washington University in St. Louis (WashU) welcomes hundreds of new engineering students to its McKelvey School of Engineering. Historically, during orientation activities, WashU’s Engineering Student Services (ESS) serves dessert bars to the new students, where they must line up and make their own desserts manually. To make the dessert bar more interactive and give students a primer for what their engineering studies hold, we would like to introduce an ice cream sundae making machine to the spread. A semi-automated ice cream machine would allow students to customize their ice cream sundae while observing the everyday mechanics required to …


Asme 2020 Design Challenge, Anthony Acosta, Justine Alandy-Dy, Michael Lorberg, Nathan Vaska Dec 2019

Asme 2020 Design Challenge, Anthony Acosta, Justine Alandy-Dy, Michael Lorberg, Nathan Vaska

Mechanical Engineering Design Project Class

Our project was to build a machine that would fulfill the requirements for the ASME 2020 design challenge, which was called, ”Building to the Sky.” The rules of the challenge were to build a machine that would take ordinary 8.5” x 11” sheets of paper and stack them into a tower. To accomplish this task, we decided to make our paper tower out of accordion-shaped folds that would be placed on top of each other, alternating in 90 degree orientations. Our device is divided into various sub-components, each which manipulate the paper in various ways. We first have a mechanism …


3d Chocolate Printer Dropper, Jessica Jimenez, Jacqueline Pielli, Shuhan Zhang Dec 2019

3d Chocolate Printer Dropper, Jessica Jimenez, Jacqueline Pielli, Shuhan Zhang

Mechanical Engineering Design Project Class

The Mechanical Engineering Department at Washington University in St. Louis is working to stimulate interest in the fields of fluid dynamics and thermal sciences, as students are not typically exposed to these topics within the first two years of school. Dr. Okamoto, Jeff Krampf, and Dr. Weisensee of the Mechanical Engineering Department would like to remedy this situation by developing a laboratory experiment for first year students that utilizes a 3D chocolate printer to teach thermal-fluid concepts in a fun and engaging manner. The goal of this project is to build a chocolate droplet dispensing system, which is a part …


Board Erasing Device, Mark Fernandez, Christopher Sheffels, Joshua Miller Dec 2019

Board Erasing Device, Mark Fernandez, Christopher Sheffels, Joshua Miller

Mechanical Engineering Design Project Class

The Board Erasing Device is a portable automatic device designed to streamline a university lecturer’s board writing process by automatically erasing whiteboards while they are writing notes on adjacent boards. Our goal during this project was to design, build, and test a portable, automatic, and aesthetically pleasing device compatible with most standard whiteboards on Washington University in St. Louis’ Danforth campus. To that end, with a budget of $400, we created a prototype device to accomplish just that. Our prototype includes a felt eraser, pressed into the whiteboard via magnets. The eraser piece spans all eight feet of width on …


Diver Propulsion Wearable, Joseph Lucca Paletta, Andrew Kessler, Andrew Beukelman, Nico Topulos Dec 2019

Diver Propulsion Wearable, Joseph Lucca Paletta, Andrew Kessler, Andrew Beukelman, Nico Topulos

Mechanical Engineering Design Project Class

This project was proposed by Jin Hwan (Josh) An, a current undergraduate student in the Olin Business School at Washington University in St Louis. Given his interest in diving and his experience with current diver propulsion vehicles, Josh has challenged us to design a hands-free diver propulsion wearable (DPW). While Josh has left the project rather open-ended for the engineers, the main challenge is to create a design that can propel the diver using a hands-free control system. Having a hands-free controller will allow the user to engage in other tasks while gliding underwater. Ideally, this design would be useful …


Mems 411: Improved Greens Harvester, Matthew Celentano, Nicholas Watts, Sam Friedrich, Ava Mennin Dec 2019

Mems 411: Improved Greens Harvester, Matthew Celentano, Nicholas Watts, Sam Friedrich, Ava Mennin

Mechanical Engineering Design Project Class

Earth Dance Organic Farm School has asked that we design an improved version of their “Quick-Cut” greens harvester. The redesign should be capable of cutting a 36 inch wide bed of greens, should roll on wheels, and should be able to operate for long periods without interruption. This report details the concept generation and selection phases of the project, wherein we elect to design the system with an aluminum extrusion frame, four- wheeled custom band saw system, and rope sweepers, among other key features. In the concept embodiment phase, we explore the features of our initial prototype and areas for …


Reducing Soil Compaction In Agriculture, Chris Gum, Justin Manzella, Brett Kayman Aug 2019

Reducing Soil Compaction In Agriculture, Chris Gum, Justin Manzella, Brett Kayman

Washington University / UMSL Mechanical Engineering Design Project JME 4110

Our project was to prototype a device to reduce compaction in soil during industrial agricultural processes. We chose to highlight tilling as the process to focus on, but our final design could be adapted to work for many different applications.


Alternative Approach To Sand Bags For Flood Prevention Through The Use Of 3d Printed Flood Panels, Thomas Beaver, William Mcbryan, Matthew Gilliam Aug 2019

Alternative Approach To Sand Bags For Flood Prevention Through The Use Of 3d Printed Flood Panels, Thomas Beaver, William Mcbryan, Matthew Gilliam

Washington University / UMSL Mechanical Engineering Design Project JME 4110

This is an alternative approach to sand bags which could save time and money when implementing temporary barriers around critical areas during times of flooding in flood plains or areas near rivers.


Mechanosensitive Epithelial Cell Scattering And Migration On Layered Matrices, Christopher Michael Walter Aug 2019

Mechanosensitive Epithelial Cell Scattering And Migration On Layered Matrices, Christopher Michael Walter

McKelvey School of Engineering Theses & Dissertations

Epithelial cells form multi-layered tissue scaffolding that makes up every organ in the body. Along with epithelial cells, the basement membrane (BM) and connective tissue are composed of various proteins that sculpt the organs and protect them from foreign macromolecules. Epithelial cells respond to various cues, both chemical and mechanical, from their surrounding matrices to aid in maintenance and repair of these layers through degradation and deposition of extracellular matrix (ECM) proteins. In cancer progression, epithelial cells lose their normal function of supporting tissue structure and instead adopt more aggressive behaviors through an epithelial-to-mesenchymal transition (EMT) of their cellular traits. …