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- Adjoint sensitivity analysis (3)
- Adjoint cooling tower model solution verification (2)
- Best-estimate predictions (2)
- Cooling tower (2)
- Data assimilation (2)
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- Model calibration (2)
- Physics, Applied Mechanical Engineering (2)
- Reduced predicted uncertainties (2)
- AIF (1)
- Calcium retention (1)
- Coenzyme Q10 (1)
- Elastodynamics (1)
- Engineering, Mechanical Engineering (1)
- Gauge condition (1)
- Glutamate toxicity (1)
- Lamb Wave (1)
- Mitochondrial fragmentation (1)
- Navier-Lame equations (1)
- Neuronal cell death (1)
- SH wave (1)
- Structural health monitoring; guided wave; damage detection; scatter cube; non-axisymmetric guided waves; sensor design (1)
Articles 1 - 6 of 6
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Predictive Modeling Of A Buoyancy-Operated Cooling Tower Under Unsaturated Conditions: Adjoint Sensitivity Model And Optimal Best-Estimate Results With Reduced Predicted Uncertainties, Federico Di Rocco, Dan Gabriel Cacuci
Predictive Modeling Of A Buoyancy-Operated Cooling Tower Under Unsaturated Conditions: Adjoint Sensitivity Model And Optimal Best-Estimate Results With Reduced Predicted Uncertainties, Federico Di Rocco, Dan Gabriel Cacuci
Faculty Publications
Nuclear and other large-scale energy-producing plants must include systems that guarantee the safe discharge of residual heat from the industrial process into the atmosphere. This function is usually performed by one or several cooling towers. The amount of heat released by a cooling tower into the external environment can be quantified by using a numerical simulation model of the physical processes occurring in the respective tower, augmented by experimentally measured data that accounts for external conditions such as outlet air temperature, outlet water temperature, and outlet air relative humidity. The model’s responses of interest depend on many model parameters including …
Predictive Modeling Of A Paradigm Mechanical Cooling Tower Model: Ii. Optimal Best-Estimate Results With Reduced Predicted Uncertainties, Ruixian Fang, Dan Gabriel Cacuci, Madalina Badea
Predictive Modeling Of A Paradigm Mechanical Cooling Tower Model: Ii. Optimal Best-Estimate Results With Reduced Predicted Uncertainties, Ruixian Fang, Dan Gabriel Cacuci, Madalina Badea
Faculty Publications
This work uses the adjoint sensitivity model of the counter-flow cooling tower derived in the accompanying PART I to obtain the expressions and relative numerical rankings of the sensitivities, to all model parameters, of the following model responses: (i) outlet air temperature; (ii) outlet water temperature; (iii) outlet water mass flow rate; and (iv) air outlet relative humidity. These sensitivities are subsequently used within the “predictive modeling for coupled multi-physics systems” (PM_CMPS) methodology to obtain explicit formulas for the predicted optimal nominal values for the model responses and parameters, along with reduced predicted standard deviations for the predicted model parameters …
Predictive Modeling Of A Paradigm Mechanical Cooling Tower: I. Adjoint Sensitivity Model, Dan Gabriel Cacuci, Ruixian Fang
Predictive Modeling Of A Paradigm Mechanical Cooling Tower: I. Adjoint Sensitivity Model, Dan Gabriel Cacuci, Ruixian Fang
Faculty Publications
Cooling towers discharge waste heat from an industrial process into the atmosphere, and are essential for the functioning of large energy-producing plants, including nuclear reactors. Using a numerical simulation model of the cooling tower together with measurements of outlet air relative humidity, outlet air and water temperatures enables the quantification of the rate of thermal energy dissipation removed from the respective process. The computed quantities depend on many model parameters including correlations, boundary conditions, material properties, etc. Changes in these model parameters will induce changes in the computed quantities of interest (called “model responses”). These changes are quantified by the …
Using The Gauge Condition To Simplify The Elastodynamic Analysis Of Guided Wave Propagation, Bhuiyan Yeasin Md, Victor Giurgiutiu
Using The Gauge Condition To Simplify The Elastodynamic Analysis Of Guided Wave Propagation, Bhuiyan Yeasin Md, Victor Giurgiutiu
Faculty Publications
In this article, gauge condition in elastodynamics is explored more to revive its potential capability of simplifying wave propagation problems in elastic medium. The inception of gauge condition in elastodynamics happens from the Navier-Lame equations upon application of Helmholtz theorem. In order to solve the elastic wave problems by potential function approach, the gauge condition provides the necessary conditions for the potential functions. The gauge condition may be considered as the superposition of the separate gauge conditions of Lamb waves and shear horizontal (SH) guided waves respectively, and thus, it may be resolved into corresponding gauges of Lamb waves and …
Guided Wave Based Crack Detection In The Rivet Hole Using Global Analytical With Local Fem Approach, Bhuiyan Yeasin Md, Yanfeng Shen, Victor Giurgiutiu
Guided Wave Based Crack Detection In The Rivet Hole Using Global Analytical With Local Fem Approach, Bhuiyan Yeasin Md, Yanfeng Shen, Victor Giurgiutiu
Faculty Publications
In this article, ultrasonic guided wave propagation and interaction with the rivet hole cracks has been formulated using closed-form analytical solution while the local damage interaction, scattering, and mode conversion have been obtained from finite element analysis. The rivet hole cracks (damage) in the plate structure gives rise to the non-axisymmetric scattering of Lamb wave, as well as shear horizontal (SH) wave, although the incident Lamb wave source (primary source) is axisymmetric. The damage in the plate acts as a non-axisymmetric secondary source of Lamb wave and SH wave. The scattering of Lamb and SH waves are captured using wave …
Ubisol-Q10 Prevents Glutamate-Induced Cell Death By Blocking Mitochondrial Fragmentation And Permeability Transition Pore Opening, Santosh Kumari, Suresh L. Mehta, Gaolin Z. Milledge, Xinyu Huang, P Andy Li
Ubisol-Q10 Prevents Glutamate-Induced Cell Death By Blocking Mitochondrial Fragmentation And Permeability Transition Pore Opening, Santosh Kumari, Suresh L. Mehta, Gaolin Z. Milledge, Xinyu Huang, P Andy Li
Faculty Publications
Mitochondrial dysfunction and oxidative stress are the major events that lead to the formation of mitochondrial permeability transition pore (mPTP) during glutamate-induced cytotoxicity and cell death. Coenzyme Q10 (CoQ10) has widely been used for the treatment of mitochondrial disorders and neurodegenerative diseases. Comparing to traditional lipid-soluble CoQ10, water soluble CoQ10 (Ubisol-Q10) has high intracellular and intra-mitochondrial distribution. The aims of the present study are to determine the neuroprotective effects of Ubisol-Q10 on glutamate-induced cell death and to explore its functional mechanisms. HT22 neuronal cells were exposed to glutamate. Cell viability was measured and mitochondrial fragmentation was assessed by mitochondrial imaging. …