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Bioprinting A 3d Tubular Structure With Vascular Smooth Muscle Cells To Observe The Process Compatibility, Taieba Tuba Rahman
Bioprinting A 3d Tubular Structure With Vascular Smooth Muscle Cells To Observe The Process Compatibility, Taieba Tuba Rahman
Theses and Dissertations
Printability is the ability to print a reproducible structure using the bioprinting technique. Constructing the relationships between printability and printing parameters of the extrusion printing process is difficult because of the presence of too many independent and inter-correlated factors. For this reason, it is necessary to identify and limit the number of significantly influential factors. In addition, Scaffold based blood vessel fabrication is a key challenge in 3D Bioprinting. As vascular smooth muscle cell (VSMCs) is a major component of blood vessels, the investigation of the behavior and orientation of VSMCs after printing is required to better understand the 3D …
Discrete Element Modeling Of Hydrogel Extrusion, Rohit Boddu
Discrete Element Modeling Of Hydrogel Extrusion, Rohit Boddu
Theses and Dissertations
Hydrogels are widely used in extrusion bioprinting as bioinks. Understanding how the hydrogel microstructure affects the bioprinting process aids researchers in predicting the behavior of biological components. Current experimental tools are unable to measure internal forces and microstructure variations during the bioprinting process. In this work, discrete element modeling was used to study the internal interactions and the elastic deformation of the molecular chains within hydrogel networks during the extrusion process. Two-dimensional models of hydrogel extrusions were created in Particle Flow Code (PFC; Itasca Co., Minneapolis, MN). For our model's calibration, hydrogel compression testing was used in which a cluster …