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In Vitro Assessment Of The Effects Of Valvular Stenosis On Aorta Hemodynamics And Left Ventricular Function, Ashish Madan
In Vitro Assessment Of The Effects Of Valvular Stenosis On Aorta Hemodynamics And Left Ventricular Function, Ashish Madan
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Calcific aortic stenosis (CAS) is the most common valvular heart disease and is associated with aortopathy and ventricular dysfunction. Hemodynamic alterations due CAS could affect the aorta lining (endothelium), that is in direct contact with the blood, triggering adverse biological responses that may possibly cause aortic dilation and dissection. Also, CAS could impose excessive ventricular load leading to ventricular wall thickening, thus putting an individual at a higher risk of heart attack or stroke. These pathophysiological effects of CAS are highly dependent on the degree of calcification. However, the impact of CAS development on aorta flow and left ventricular workload …
Measurement Of Unsteady Characteristics Of Endwall Vortices Using Surface-Mounted Hot-Film Sensors, Emma Michelle Veley
Measurement Of Unsteady Characteristics Of Endwall Vortices Using Surface-Mounted Hot-Film Sensors, Emma Michelle Veley
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High-lift low-pressure turbine blades produce significant losses at the junction with the endwall. The losses are caused by several complex three-dimensional vortical flow structures, which interact with the blade suction surface boundary layer. This study investigates the unsteady characteristics of these endwall flow structures on a highly loaded research profile and the adjacent endwall using surface-mounted hot-film sensors. Experiments were conducted in a low-speed linear cascade wind tunnel. The front-loaded blade profile was subjected to three different inlet conditions, consisting of two turbulence levels, and three incoming boundary layer thicknesses. Multiple surface-mounted hot-film sensors were installed throughout the passage. This …