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Characterizing Mechanical Regulation Of Bone Metastatic Breast Cancer Cells, Boyuan Liu
Characterizing Mechanical Regulation Of Bone Metastatic Breast Cancer Cells, Boyuan Liu
Doctoral Dissertations
Breast cancer most frequently metastasizes to the skeleton. Bone metastatic cancer is incurable and induces wide-spread bone osteolysis, resulting in significant patient morbidity and mortality. Mechanical stimuli in the skeleton are an important microenvironmental parameter that modulates tumor formation, osteolysis, and tumor cell-bone cell signaling, but which mechanical signals are the most beneficial and the corresponding molecular mechanisms are unknown. This work focused on bone matrix deformation and interstitial fluid flow based on their well-known roles in bone remodeling and in primary breast cancer. The goal of our research was to establish a platform that could define the relationship between …
Improving The Efficiency Of Wind Farm Turbines Using External Airfoils, Shujaut Bader
Improving The Efficiency Of Wind Farm Turbines Using External Airfoils, Shujaut Bader
Masters Theses
Wind turbine efficiency typically focuses on the shape, orientation, or stiffness of the turbine blades. In this thesis, the focus is instead on using static fixed airfoils in proximity to the wind turbine to control the airflow coming out of the turbine. These control devices have three beneficial effects. (1) They gather air from “higher up” where the air is moving faster on average (and therefore has more kinetic energy in it). (2) They throw the used (and slowed down air) downwards. This means that any turbines in the wind farm behind the lead turbines do not get “stale” air. …
Optimization Of Mixing In A Simulated Biomass Bed Reactor With A Center Feeding Tube, Michael T. Blatnik
Optimization Of Mixing In A Simulated Biomass Bed Reactor With A Center Feeding Tube, Michael T. Blatnik
Masters Theses 1911 - February 2014
Producing gasoline-type fuels from lignocellulosic biomass has two advantages over producing alcohol-type fuels from plant sugars: gasoline has superior fuel characteristics and plant lignin/cellulose does not compete with human food supplies. A promising technology for converting lignocellulose to fuel is catalytic fast pyrolysis (CFP). The process involves injecting finely ground biomass into a fluidized bed reactor (FBR) at high temperatures, which reduce the biomass to gases that react inside the catalyst particles. This entails complex hydrodynamics to efficiently mix a stream of biomass into a catalyst bed that is fluidized by a separate stream of inert gas. Understanding the hydrodynamics …