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Distribution Of Tremorogenic Activity Among The Majorsuperficial Muscles Of The Upper Limb Insubjects With Essential Tremor, David Jordan Standring

Theses and Dissertations

Optimized peripheral tremor suppression could address many limitations of surgical or medicinal treatments of Essential Tremor, however it is not well understood how the tremorogenic activity is distributed among the muscles of the upper limb, and therefore how to optimize such suppression. We recorded electromyographic (EMG) activity in the 15 major superficial muscles from the shoulder to the wrist while subjects performed postural and kinetic tasks similar to activities of daily living. We calculated the power spectral density and computed the total power in the tremor band (4"12 Hz) for each muscle, from which we determined the distribution of tremorogenic …

Simulated Tremor Propagation In The Upper Limb: From Muscle Activity To Joint Displacement, Thomas Corie, Steven Knight Charles

Faculty Publications

Although tremor is the most common movement disorder, there are few non-invasive treatment options. Creating effective tremor suppression devices requires a knowledge of where tremor originates mechanically (which muscles) and how it propagates through the limb (to which degrees of freedom, DOF).

To simulate tremor propagation, we created a simple model of the upper limb, with tremorogenic activity in the 15 major superficial muscles as inputs and tremulous joint displacement in the 7 major DOF as outputs. The model approximated the muscle excitation-contraction dynamics, musculoskeletal geometry, and mechanical impedance of the limb.

From our simulations, we determined fundamental principles for …

Proof-Of-Concept Tremor Suppression Sleeve For Essential Tremor Patients, S. Adam Stringham, Dr. Steven K. Clarles

Journal of Undergraduate Research

Essential Tremor (ET) is among the most common movement disorders. It is characterized by involuntary, rhythmic movement in the body, most often in the hands or head. The primary treatment options include deep brain surgery and/or medication, both of which can cause undesired side effects. The Neuromechanics Research Group at BYU is investigating alternative treatments by studying the effect of low-level electrical stimulation of affected extrinsic hand muscles on tremor in ET patients. While the research may prove promising, there are still several obstacles to overcome for this approach to be practical. To apply electrical stimulation, self-adhesive electrodes are placed …

Distribution Of Essential Tremor In The Degrees Of Freedom Of The Upper Limb, Charles Charles Pigg

Theses and Dissertations

This study seeks to understand upper limb tremor in subjects with essential tremor (ET). A thorough understanding of tremor distribution will allow for the more effective development of tremor suppression devices, which offer an alternative to current treatments. Previous studies primarily focused on tremor in the hand only. This study seeks to characterize the distribution of tremor throughout the upper limb. We measured tremor in 25 subjects diagnosed with ET using motion capture, which provided 0displacement information of the limb during multiple postural and kinetic tasks. Inverse kinematics allowed us to analyze the motion capture data in the 7 major …

Distribution Of Essential Tremor In The Degrees Of Freedom Of The Upper Limb, Adam Charles Pigg

Theses and Dissertations

This study seeks to understand upper limb tremor in subjects with essential tremor (ET). A thorough understanding of tremor distribution will allow for the more effective development of tremor suppression devices, which offer an alternative to current treatments. Previous studies primarily focused on tremor in the hand only. This study seeks to characterize the distribution of tremor throughout the upper limb.We measured tremor in 25 subjects diagnosed with ET using motion capture, which provided displacement information of the limb during multiple postural and kinetic tasks. Inverse kinematics allowed us to analyze the motion capture data in the 7 major degrees …

Characterization Of Postural Tremor In Essential Tremor Using A Seven-Degree-Of-Freedom Model, Daniel William Geiger

Theses and Dissertations

Essential Tremor (ET), a condition characterized by postural and kinetic tremor in the upper limbs, is one of the most prevalent movement disorders. While pharmaceutical and surgical treatment options exist, they are not ideal. Assistive devices have the potential to provide relief to patients but are largely unexplored for ET. Furthermore, prior characterizations of essential tremor have focused on endpoint tremor and provide insufficient detail for designing such a device. We propose and demonstrate a novel method for characterizing essential tremor in the 7 proximal degrees of freedom (DOF) of the upper limb in various postures. In addition, we provide …