Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 1 of 1
Full-Text Articles in Entire DC Network
Burst Pressure Properties And Ex Vivo Analysis Of Alginate-Based Hydrogels For Tissue Sealant Applications, Patrick Nelson Charron
Burst Pressure Properties And Ex Vivo Analysis Of Alginate-Based Hydrogels For Tissue Sealant Applications, Patrick Nelson Charron
Graduate College Dissertations and Theses
Lung diseases, cancers, and trauma can result in injury to the connective tissue lining the lung, i.e., the pleura. Pleural injuries lead to pneumothoraxes or pleural effusions, i.e., air or fluid leaking out of the lung respectively, and potential lung collapse - an immediately life threatening condition. While several bioengineered soft tissue sealants exist on the market, there is only one sealant FDA-approved for use in pulmonary surgery. In addition, very limited techniques are presented in the literature for characterizing the burst properties of hydrogel tissue sealants. For my thesis, I proposed to develop a protocol for characterizing the burst …