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Mechanical Engineering

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Clemson University

Theses/Dissertations

2019

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Cavopulmonary Support For Failing Fontan Patients: Computational And In Vitro Assessment, Masoud Farahmand Dec 2019

Cavopulmonary Support For Failing Fontan Patients: Computational And In Vitro Assessment, Masoud Farahmand

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Congenital heart defects are responsible for the mortality of approximately 300,000 newborn each year. One study in 2010 estimated that over 2 million patients were living with congenital heart defects in the United States. Congenital heart defects have the highest hospitalization cost among other birth defect categories. The damage on the U.S economy in 2013 was estimated $6.1 billion. The most complex and severe form of these defects results in single ventricle physiology. Fortunately, over the last 50 years, these patients have been able to survive into adulthood as a result of three stages of surgeries culminating with Fontan operation. …