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Modeling Core Generation And Transport Phenomena Of Microcapsules, Xiaoshuo Wu

Doctoral Dissertations

Microcapsules play an important role in chemical, biomedical, and medical research. Of importance is their potential use as bio-sensors, as microreactors, and for drug delivery. In this dissertation, Computational Fluid Dynamics methodology is used to model the generation of droplets or cores (using alginate and oil) and to determine from the model process parameters needed for generating cores of homogeneous size for the manufacturing of microcapsules. Also, material diffusion through a microcapsule for controlled release is modeled based on finite difference methodology. The model was applied to experimental data on dextran release from microcapsules in order to estimate the diffusion …