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Functional Data Analysis And Its Application To Cancer Data, Evgeny Martinenko

Electronic Theses and Dissertations

The objective of the current work is to develop novel procedures for the analysis of functional data and apply them for investigation of gender disparity in survival of lung cancer patients. In particular, we use the time-dependent Cox proportional hazards model where the clinical information is incorporated via time-independent covariates, and the current age is modeled using its expansion over wavelet basis functions. We developed computer algorithms and applied them to the data set which is derived from Florida Cancer Data depository data set (all personal information which allows to identify patients was eliminated). We also studied the problem of …