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Hypersurfaces In Hyperbolic Space With Support Function, Vincent Bonini, José M. Espinar, Jie Qint
Hypersurfaces In Hyperbolic Space With Support Function, Vincent Bonini, José M. Espinar, Jie Qint
Mathematics
Based on [previous publication*], we develop a global correspondence between immersed hypersurfaces ϕ:Mn→Hn+1ϕ:Mn→Hn+1 satisfying an exterior horosphere condition, also called here horospherically concave hypersurfaces, and complete conformal metrics e2ρgSne2ρgSn on domains Ω in the boundary SnSn at infinity of Hn+1Hn+1, where ρ is the horospherical support function, ∂∞ϕ(Mn)=∂Ω∂∞ϕ(Mn)=∂Ω, and Ω is the image of the Gauss map G:Mn→SnG:Mn→Sn. To do so we first establish results on when the Gauss map G:Mn→SnG:Mn→Sn is injective. We also …
An Analysis Of Strategic Treatment Interruptions During Imatinib Treatment Of Chronic Myelogenous Leukemia With Imatinib-Resistant Mutations, Dana Paquin, David Sacco, John Shamshoian
An Analysis Of Strategic Treatment Interruptions During Imatinib Treatment Of Chronic Myelogenous Leukemia With Imatinib-Resistant Mutations, Dana Paquin, David Sacco, John Shamshoian
Mathematics
Chronic myelogenous leukemia (CML) is a cancer of the white blood cells that results from increased and uncontrolled growth of myeloid cells in the bone marrow and the accumulation of these cells in the blood. The most common form of treatment for CML is imatinib, a tyrosine kinase inhibitor. Although imatinib is an effective treatment for CML and most patients treated with imatinib do attain some form of remission, imatinib does not completely eradicate all leukemia cells, and if treatment is stopped, all patients eventually relapse (Cortes, 2005). In Kim (2008), the authors developed a mathematical model for the dynamics …