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Application Of Nano-Plasmonics For Sers Bio-Detection And Photocatalysis In The Same Platform, Muhammad R. Shattique
Application Of Nano-Plasmonics For Sers Bio-Detection And Photocatalysis In The Same Platform, Muhammad R. Shattique
MSU Graduate Theses
Nano-biological systems interfacing nano-structured solid surfaces with biological compounds such as oligonucleotides or proteins are highly regarded as enabling materials for biosensing and biocatalysis applications. In particular, nanostructures of noble metals such as gold or silver, when exposed to light, exhibit a phenomenon known as surface plasmon resonance. When a proper metal nanostructure (plasmonic substrate) is exposed to light, very efficient absorption of incoming photons is possible, resulting in a buildup of localized high-energy regions, or “hot-spots”, where energetic carriers or “hot carriers” can be created. These hot-carriers can be used to catalyze desired chemical transformations in materials located nearby. …
Application Of Raman Spectroscopy To Study Of Biological Systems, Neva Agarwala
Application Of Raman Spectroscopy To Study Of Biological Systems, Neva Agarwala
MSU Graduate Theses
Raman spectroscopy is an important tool of molecular characterization based on inelastic scattering of monochromatic light by molecules. Since Raman spectra reflect unique vibrational properties of materials, the method offers a potential of selective molecular identification. Furthermore, surface-enhanced Raman spectroscopy (SERS) also is capable of a high sensitivity, since inelastic scattering of light from the molecules is strongly enhanced when Raman-active molecules are located close to roughened noble metal surfaces. In this thesis, Raman characterization protocols of liquid biological samples are optimized. Raman spectra of two different cell cultures, yeast cells and HeLa cells, were collected and interpreted. The potentiality …
A Study On The Synthesis And Properties Of Gold Nanoparticles And Their Applications To Surface Enhanced Raman Spectroscopy, Daniel Robert Soden
A Study On The Synthesis And Properties Of Gold Nanoparticles And Their Applications To Surface Enhanced Raman Spectroscopy, Daniel Robert Soden
MSU Graduate Theses
Surface enhanced Raman substrates represent a critical step in the sensitivity augmentation of Raman spectroscopy, but due to the time and expertise currently required in the synthesis process, they have not been fully realized within an industrial setting. This thesis aims to investigate a new technique in surface enhanced Raman spectroscopy (SERS) substrate fabrication designed to decrease synthesis time and map the most effective growth parameters for a successful Raman intensity boost. Sputter physical vapor deposition was utilized to deposit a gold (Au) layer on an insulating substrate, and annealing treatments were applied to agglomerate the Au atoms into the …