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Systematic Study Of The Biological Effects Of Nitric Oxide (No) Using Innovative No Measurement And Delivery Systems, Weilue He Jan 2015

Systematic Study Of The Biological Effects Of Nitric Oxide (No) Using Innovative No Measurement And Delivery Systems, Weilue He

Dissertations, Master's Theses and Master's Reports

Nitric oxide (NO) is recognized as the most important small signaling molecule in the human body. An imbalance of NO is closely associated with many serious diseases such as neurological disorders, cardiovascular diseases, chronic inflammations and cancers. Herein two chemiluminescence-based devices (a real-time NO measurement device and a controllable NO delivery device) were developed to facilitate the NO quantitative study and obtain information for NO related drug design.

The first device used for real-time measuring NO(g) flux from living cells was developed and validated. The principle was to use a two-chamber design, with a cell culture chamber and a gaseous …


Biocorrosion Rate And Mechanism Of Metallic Magnesium In Model Arterial Environments, Patrick Bowen Jan 2015

Biocorrosion Rate And Mechanism Of Metallic Magnesium In Model Arterial Environments, Patrick Bowen

Dissertations, Master's Theses and Master's Reports

A new paradigm in biomedical engineering calls for biologically active implants that are absorbed by the body over time. One popular application for this concept is in the engineering of endovascular stents that are delivered concurrently with balloon angioplasty. These devices enable the injured vessels to remain patent during healing, but are not needed for more than a few months after the procedure. Early studies of iron- and magnesium-based stents have concluded that magnesium is a potentially suitable base material for such a device; alloys can achieve acceptable mechanical properties and do not seem to harm the artery during degradation. …


3d Printing, Open-Source Technology And Their Applications In Research, Chenlong Zhang Jan 2015

3d Printing, Open-Source Technology And Their Applications In Research, Chenlong Zhang

Dissertations, Master's Theses and Master's Reports

Open-source software received tremendous success as it drives down the cost of software and expand the distribution. Open-source hardware, as part of the open-source movement, has just risen into public attention for its potential to further drive down the cost of all kinds of manufacturing goods and reshape the manufacture chain. In this report we explores the history, development and the future of open-source hardware project, summarizing the opportunities, challenges and possible solutions. 3D printing is demonstrated as a booster to assist open-source hardware’s development. Low-cost 3D printer enables at-home and in-time fabrication, the download-print-use-improve-distribute cycle is established to encourage …