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Phasic Response Of Peripheral Nerves To Inflammation, Ralph Lee Myers

University of the Pacific Theses and Dissertations

Acute inflammation is associated with injury to tissues, whether it be from mechanical destruction, or from the introduction of a noxious substance into the tissue. Inflammation is a homeostatic process, adapted to neutralize harmful substances and restore injured tissue. Celsus (c. A.D. 178) provided the first documented characterization of inflammation. He recognized redness, heat, swelling and pain as the cardinal signs of the inflammatory reaction. Loss of function was later added to this list of symptons (Movat. 1971).