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Cache Valley Resident Exposure To Pm2.5, Kristina Krepinski Jul 2017

Cache Valley Resident Exposure To Pm2.5, Kristina Krepinski

Undergraduate Honors Capstone Projects

Air pollution poses one of the largest environmental risks to human health, and greatly contributes to increased mortality within populations. Of the different types of pollutants, fine particulate matter (PM2.5) has the most adverse health effects. Long-term exposure to PM2.5 is known to have serious health outcomes; however, evidence has indicated that even short-term exposure to moderate concentrations of PM2.5 is detrimental to human health. While PM2.5 does contribute to various respiratory conditions by affecting lung function, it also significantly affects the cardiovascular system. Elevated PM2.5 exposure increases risk for cardiovascular disease, congestive heart …


Dietary Supplementation With Tart Cherries For Prevention Of Inflammation-Associated Colorectal Cancer In Mice, Ashlie Hunter May 2017

Dietary Supplementation With Tart Cherries For Prevention Of Inflammation-Associated Colorectal Cancer In Mice, Ashlie Hunter

Undergraduate Honors Capstone Projects

The cherry fruit is a nutrient-dense food with comparatively low caloric content and significant amounts of key nutrients and bioactive food chemicals. Much of the health benefit of cherries is attributed to their high amounts of anthocyanins, which have anti-oxidant and anticancer properties that contribute to changes in cell signaling pathways involved in inflammation, carcinogenesis and angiogenesis. In this project, we aimed to determine whether dietary supplementation with tart cherries prevents colon tumor development in mice consuming a Western diet compared to a prudent diet. Previously, our research team developed the Total Western Diet (TWD) for mice to emulate typical …