Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 1 of 1
Full-Text Articles in Entire DC Network
The Use Of The Xylose Tolerance Test As An Indicator Of Malabsorption In Cryptosporidiosis, James A. Evans
The Use Of The Xylose Tolerance Test As An Indicator Of Malabsorption In Cryptosporidiosis, James A. Evans
Undergraduate Honors Capstone Projects
Cryptosporidium parvum, a protozoan parasite infecting epithelial cells lining the intestinal tract of animals and humans, causes fulminate diarrhea and malabsorption of essential nutrients following damage to the cellular brush border. The present study was undertaken to evaluate the use of a pentose sugar (D-xylose) in a standardized tolerance test as an indicator of malabsorption due to cryptosporidiosis in the dexamethasone (DEX)-immunosuppressed adult C57BL/6N mouse model. One group containing 14 experimental mice (in addition to appropriate control groups) was immunosuppressed using daily intraperitoneal injections of DEX (125 μg/mouse). On day 7 postimmunosuppression, mice were inoculated orally with 104 C. …