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Exercise-Induced Hypoxia, Angiogenesis, And Behavioral Flexibility In The Adult Rat, Kiersten Lee Berggren
Exercise-Induced Hypoxia, Angiogenesis, And Behavioral Flexibility In The Adult Rat, Kiersten Lee Berggren
Theses and Dissertations
Exercise induces a myriad of effects on the brain from the growth of new capillaries and neurons, to improvements in cognitive performance. Additionally, recent research has shown that commencement of an exercise regimen also causes apoptosis. Therefore, it is possible that exercise-induced increases in oxygen demand cause the brain to transiently experience a state of hypoxia. To investigate this hypothesis, we measured protein levels of hypoxia inducible factor 1 alpha (HIF-1α), a transcription factor known to be upregulated in conditions of hypoxia or ischemia, in animals exposed to a single bout of treadmill exercise. After exercise animals were sacrificed at …
The Effect Of Anterior Knee Pain On Serum Cartilage Oligomeric Matrix Protein And Muscular Cocontraction During Running, Scott T. Woodland
The Effect Of Anterior Knee Pain On Serum Cartilage Oligomeric Matrix Protein And Muscular Cocontraction During Running, Scott T. Woodland
Theses and Dissertations
Knee pain can alter lower-extremity neuromechanics and often results in functional disability. The relationship between lower-extremity neuromechanical alterations, due to anterior knee pain, and articular cartilage condition is unclear. The purpose of this study was to determine the independent effect of anterior knee pain during running on articular cartilage condition, as reflected by serum cartilage oligomeric matrix protein concentrations and muscle cocontraction duration. Seven men and five women completed a 30-min run in three different sessions: control (no infusion), sham (isotonic saline infusion), and pain (hypertonic saline infusion). Saline was infused into the right infrapatellar fat pad for the duration …
The Effect Of Cancer Cachexia Severity And Eccentric Muscle Contractions On Selected Myofiber Metabolic Properties In Mouse Skeletal Muscle, Joshua Earl Mangum
The Effect Of Cancer Cachexia Severity And Eccentric Muscle Contractions On Selected Myofiber Metabolic Properties In Mouse Skeletal Muscle, Joshua Earl Mangum
Theses and Dissertations
Cancer cachexia is a complex syndrome that induces skeletal muscle wasting and dysregulation of skeletal muscle metabolism. Alterations in area of myofibers and myofiber metabolic properties can significantly impact the function of skeletal muscle. The purpose of this study was to examine the effect of cachexia severity and resistance exercise training on frequency and area of selected myofiber metabolic characteristics during cachexia-induced myofiber atrophy. Male ApcMin/+ (Min) mice were studied during the progression of cachexia (16-20 weeks of age) and stratified into groups based on the severity of cachexia. For the second study, male Min mice performed resistance exercise (RE) …
Classroom Exercise Breaks And Educational Outcomes In Elementary School Students, Erin Kaye Howie
Classroom Exercise Breaks And Educational Outcomes In Elementary School Students, Erin Kaye Howie
Theses and Dissertations
Previous research has shown that physical activity may have beneficial effects on cognitive performance and academic achievement in children, but the optimal type and dose are unknown. Classroom exercise breaks are one type of physical activity opportunity in schools, with the potential to reach a large number of children. The purpose of this dissertation was to describe the prevalence and characteristics of classroom exercise breaks in central South Carolina, and to determine the acute effects of classroom exercise breaks on executive functions, math performance, on-task behavior and affective responses in 9 to 12 year-old children. Additionally, the dissertation examined the …