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Metabolic Inhibition Of A Toluene-Enriched Microbial Population Due To Lead (Pb2+): Verification Of A Free Metal Ion Toxicity Model, Patrick J. S. Marbas
Metabolic Inhibition Of A Toluene-Enriched Microbial Population Due To Lead (Pb2+): Verification Of A Free Metal Ion Toxicity Model, Patrick J. S. Marbas
Theses and Dissertations
A dissolved oxygen probe and an ion specific electrode were used to study the lead-induced metabolic inhibition in a toluene-enriched microbial population. Predicted toxicity values were compared to the actual toxicity responses using a free metal ion toxicity model (TM) which linked metabolic inhibition with lead activity. Experimentally derived values for the model parameters (lead activity and a lead distribution coefficient) were used in the TM. It was postulated that cellular metabolism is disrupted by the conformational changes to the cell's plasma membrane produced by lead ion adsorption. The predicted toxicity values were higher than the actual toxicity response. This …