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Cell Size Control And Asymmetric Cell Fates In Start Of The Saccharomyces Cerevisiae Cell Cycle, Talia, Stefano Di
Cell Size Control And Asymmetric Cell Fates In Start Of The Saccharomyces Cerevisiae Cell Cycle, Talia, Stefano Di
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Understanding the molecular and biophysical mechanisms that couple the process of cell growth to cell division is one of the major challenges of modern cell biology. Saccharomyces cerevisiae (budding yeast) has been an important model organism to study the coupling between cell growth and cell division. The insights obtained from studies of this unicellular organism have been pivotal for related studies in animal systems. The classical picture that emerged from studies in budding yeast was that cell cycle commitment in G1, at a point called Start, requires growth to a critical cell size. This deterministic model did not address how …