Open Access. Powered by Scholars. Published by Universities.®
- Keyword
-
- Allylic alcohols (1)
- Asymmetric transfer (1)
- Bacterioopsin gene (Bop) (1)
- Cadmium (1)
- Chironomid (1)
-
- Drosophila pseudoobscura (1)
- GPCR characterization (1)
- Halobacterium salinartum (H sal) (1)
- Heavy metal toxicants (1)
- Homogeneous chiral ruthenium catalysts (1)
- LPS-induced activation of hepatic map kinases (1)
- Lipopolysaccharide (1)
- Molecular biomarkers (1)
- Spermatogenesis (1)
- Spermatogenic cysts (1)
- Stem loop structure (1)
- Toxicity (1)
Articles 1 - 5 of 5
Full-Text Articles in Entire DC Network
Modulation Of Lps-Induced Activation Of Hepatic Map Kinases, Oliver Surriga
Modulation Of Lps-Induced Activation Of Hepatic Map Kinases, Oliver Surriga
Seton Hall University Dissertations and Theses (ETDs)
Lipopolysaccharide (LPS) is a potent inflammagen that has been found to be primarily responsible for many symptoms caused by gram-negative bacterial infections. The LPS-initiated signal transduction pathways involve several terminal kinases, mainly p42/44 mitogen-activated protein kinase (MAPK), p38 MAPK and c-Jun N-terminal kinase (JNK), ultimately leading to increased expression of genes encoding such inflammatory cytokines as interleukin (IL )-1 �. IL-6 and tumor necrosis factors (TNF)-u. In this study, the effects of age on LPS-induced activation of MAPKs in the liver of rats were examined. Results show that the basal level of phosphorylated p42/44 MAPK was increased in postnatal day …
Spermiogenesis And In Vitro Culture Of Spermatogenic Cysts In Drosophila Pseudoobscura, Monicah Njogu
Spermiogenesis And In Vitro Culture Of Spermatogenic Cysts In Drosophila Pseudoobscura, Monicah Njogu
Seton Hall University Dissertations and Theses (ETDs)
Spennatogenesis is a complex process that involves differentiation and morphological changes of diploid stem cells into highly specialized, haploid, motile germ cells. Many of the transformative processes involved in mammalian spermatogenesis are conserved in flies, and their study would be facilitated by the availability of a reliable in vitro culture system. Culture of Drosophila melanogaster spermatogenic cysts is limited in usefulness because of early degeneration of cysts, low yield of elongated spermatozoa, and rare occurrences of motile sperm. We have developed a culture system for studying fly spermatogenesis using isolated spermatogenic cysts from the testes of Drosophila pseudoobscura. This species …
The 5' Bop Gene Stem-Loop Sequence: Stability, Structure, And Function, Srikanth Tangelloju
The 5' Bop Gene Stem-Loop Sequence: Stability, Structure, And Function, Srikanth Tangelloju
Seton Hall University Dissertations and Theses (ETDs)
In pursuit of GPCR characterization, our lab chose to work with a model organism Halobacterium salinarum (H sal). This organism contains the bacterioopsin gene (bop), which encodes the protein precursor of the purple membrane protein bacterioopsin (Bop). The bacterioopsin gene (bop) was chosen as the reporter for the study. The putative stem-loop structure within the bop gene is considered to be a key component of the molecular machinery that regulates Bop synthesis. Previous work in our lab has indicated that single base pair disruptions dramatically reduced stem-loop stability (differential scanning calorimetry (DSC), circular dichroism (CD) and ultraviolet (UV) spectroscopy analysis). …
Evaluating Acute Toxicity Of Cadmium To Chironomid Using Hemoglobin As A Molecular Biomarker, Jun Taek Oh
Evaluating Acute Toxicity Of Cadmium To Chironomid Using Hemoglobin As A Molecular Biomarker, Jun Taek Oh
Seton Hall University Dissertations and Theses (ETDs)
Effects of cadmium (Cd), a heavy metal contaminant, on hemoglobin were investigated in aquatic midge fly larvae of the Family, Chironomidae. In this study, chironomid populations from one polluted site, Kearny Marsh, New Jersey, two reference sites, North East Creek, and Bass Harbor, ME, and a laboratory population were taxonomically identified and tested for their sensitivity to Cd. Heavy metals in tissue, water and sediment were analyzed using Atomic Absorption Spectroscopy. Water quality at each site was assessed by measuring pH, dissolved oxygen (DO), oxidation-reduction potential ( eH), salinity and temperature. Hemoglobin proteins in individual larvae were easily detected using …
Asymmetric Transfer Hydrogenation Of Allylic Alcohols With Homogeneous Chiral Ruthenium Catalysts: A Proposed Mechanism, Marie G. Beauchamps
Asymmetric Transfer Hydrogenation Of Allylic Alcohols With Homogeneous Chiral Ruthenium Catalysts: A Proposed Mechanism, Marie G. Beauchamps
Seton Hall University Dissertations and Theses (ETDs)
.