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An Analysis Of The Involvement Of Toll Receptors In Cell Movements During The Elongation Of Tribolium Castaneum, Kathryn Russell Apr 2022

An Analysis Of The Involvement Of Toll Receptors In Cell Movements During The Elongation Of Tribolium Castaneum, Kathryn Russell

Senior Theses and Projects

Elongation of the anterior/posterior body axis is a critical part of embryonic development. Cell movements are known to play a significant role in embryo elongation in the red flour beetle Tribolium castaneum. In the arthropod model organism, Drosophila, Toll receptors have a demonstrated role in the elongation of the embryo by driving convergent extension, in which rows of cells intercalate with one another in one direction to extend tissue in the other. In Drosophila, Toll receptors are a link between anterior-posterior patterning genes expressed in discrete stripes and effector molecules causing cell movements. This cell movement is caused …


Fate Map Of The Blastoderm To Determine Segmental Fate In Tribolium Castaneum, Latanya Coke May 2019

Fate Map Of The Blastoderm To Determine Segmental Fate In Tribolium Castaneum, Latanya Coke

Senior Theses and Projects

Segmentation in arthropods has been modeled on the well-defined segmentation patterns found in Drosophila. In Drosophila, segments form simultaneously in the blastoderm where morphogenic gradients spanning the AP axis provide patterning inputs. However, in most arthropods, segments form sequentially from a posterior growth zone. Sequential segmentation in arthropods has recently been demonstrated to use a vertebrate- like segmentation clock (Sarrazin et al. 2012). The vertebrate segmentation clock is a molecular oscillator that regulates periodic somite formation (Gibb 2010). In the red flour beetle, Tribolium castaneum, the segmentation clock is coordinated by traveling waves of expression generated by a pair-rule gene …