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The Role Of P62/Imp2 In Breast Cancer Progression, Yang Li

Open Access Theses & Dissertations

Breast cancer is one of the most common types of cancer in women. In most patients with breast cancer, it is not the primary tumor that leads to death, but rather metastatic tumors. Once breast cancer spreads to other organs in the body, the disease becomes almost incurable. It is estimated that about 20% to 50% of patients diagnosed with primary breast cancer will develop metastatic disease. Considering this, it is important to understand the molecular and cellular mechanisms behind metastatic breast cancer and to identify new proteins that regulate the metastatic process. These proteins may be used as targets …