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Analysis Of The Cyc1 Promoter In Candida Albicans, Tomica Blocker

McCabe Thesis Collection

Scientists are considering two factors that may be important in the pathogenesis of C. albicans', it's capability to morph from yeast to hyphal phase, and its differences in colony morphology, cell shape, cell surface and cell permeability. (5) Unfortunately, unlike the bacteria, yeasts do not yet have proven virulence factors. However, science is suggesting that some of the major factors which contribute to the virulence of Candida are its ability to form hyphae, its ability to resist phagocytosis, its ability to adhere to epithelial cell surfaces, its ability to grow well at 37 degrees Celsius, and its ability to secrete …

Molecular Screening Of Azoreductase Gene And Its Activity In Human Intestinal Bacteria, Syndia S. Todd

McCabe Thesis Collection

The intestinal microflora are capable of performing a wide variety of metabolic transformations. "The intestinal bacteria can enhance the function of the entire gastrointestinal tract, protect against pathogenic, maintain the vital chemical balance of the gastrointestinal system, and produce needed vitamins and hormones" (http;//www.upwardquest.com/crit2.html). Some of the products of this metabolism have been associated with carcinogenic processes, such as cancer, tumor formation, gastrointestinal disease, and infections. The ability of human intestinal microbes to interact with metabolites directly or after recirculation may contribute toward different toxicological disorders and disease.

The purpose of this study is to characterize and isolate the azoreductase …

Exogenous Expression Of Human Na, K-Atpase Isoforms In Insect Cells, Christal Renee' Carpenter

McCabe Thesis Collection

The Na-K-ATPase or Na pump is a membrane bound enzyme that maintains a high concentration of K+ and low concentration of Na+ in most animal cells. Three subunits constitute the Na pump, named alpha (ex), beta (~). and gamma (y). The ex subunit is responsible for the catalytic and transport of the enzyme, the ~ subunit is important for bringing the ex to the plasma membrane of the cell, and y is a regulatory subunit of the Na pump. In addition, there are several molecular variants or isoforms of the ex and ~ subunits. At present four different ex (ex …

Does Seed Size Affect The Rate Of Germination And Early Seedling Growth In Hairy Vetch?, Joy Ekpo

McCabe Thesis Collection

Size is an important characteristic of seed quality because larger seeds with larger volume contain more resources and are likely to exhibit greater vigor than smaller seeds (Ellis, 1992). In a range of plant species, seed size has been shown to affect germination rate, emergence rate, success of establishment, and growth (Black 1957; Bentley et al. 1980; Sanderson et al. 2002). Hairy vetch is an annual legume that is used for improvement of soil for pasture and to provide ground cover protecting against erosion (Duke 1981; Undersander 2002; Sattell et al 1988). Problems facing the establishment of hairy vetch are …

Genetic Analysis Of The Putative Streptolysin O Regulator From Streptococcus Pyogenes, Robert Tyrone Billingslea

McCabe Thesis Collection

Group A streptococci (Streptococcus pyogenes) is one of the most frequent pathogens of humans. It is estimated that between 5-15% of normal individuals harbor the bacterium, usually in the upper respiratory tract, without signs of disease. S. pyogenes can initiate an active infection when defenses are compromised or when the organism is able to penetrate the host's defenses. When the bacteria invade vulnerable tissues, a variety of suppurative infections can occur. Acute S. pyogenes infection may be present as pharyngitis ("strep throat"), scarlet fever (rash), impetigo (infection of the superficial layers of the skin) or cellulitis (infection of the deep …

Moisture Potential Affects Rate Of Leaf Appearance In Cool Season Grasses, Nina Cherone Terrell

McCabe Thesis Collection

The rate of leaf appearance and onset of growth in cool season grasses may be influenced by soil moisture potential and exposure to below freezing temperatures. Levels of moisture potential and days exposed to freezing temperatures, which will restrict leaf appearance, are not well defined. The first part of this study was to determine the effects of different moisture potentials on the leaf appearance rates in two cool season grasses. Italian ryegrass (IRG) and tall wheat grass (TWG) were grown hydroponically at 4 moisture potentials in seed pouches in an incubator under a photoperiod of 13 hours light and 11 …

Analysis Of The Effects Of Hypogeal And Epigeal Emergence On Seedling Competition In Legumes, Keith E. King

McCabe Thesis Collection

Seedling emergence is either hypogeal or epigeal. In hypogeal emergence the cotyledons remain below the soil surface during seedling development, while in epigeal emergence the cotyledons extend above the soil surface due to elongation of the hypocotyl. Here we examine the effect of seed size, and emergence type, on seedling growth. Six legumes with variation in seed size and either epigeal or hypogeal emergence were grown under dark and light conditions. A competition study was also conducted where a hypogeal and epigeal legume were grown in combination with wheat and ryegrass. Legumes expressing epigeal emergence were cowpea (Vigna unguiculata), mung …

Photodynamic Therapy, Ashley Thomas

McCabe Thesis Collection

Photodynamic therapy is a new treatment that is being introduced into the veterinary community. Photodynamic therapy is the use of light activated chemotherapy to kill cancer cells (Dougherty, 1998). It has already been approved by the US Food and Drug Administration to be used as a form of cancer treatment in humans, but has not been carried over to the veterinary community. That is until now. Photodynamic therapy is now being tested in the veterinary community in hopes to find the same results that the human medical community has when dealing with certain types of cancer. They also hope to …

Do Cellular Phones Cause Headaches?, Jasmine Gay

McCabe Thesis Collection

Many people have recently complained about experiencing headaches in association with the use of their cellular telephones. There is much controversy over this subject because it has not yet been proven that the microwaves emitted by cellular telephones cause headaches. The research questions include the following: What are the effects, if any, of the use of cellular telephones on human health? Do they cause headaches? Are they responsible for the increase in size of some brain tumors?

There have been many experiments performed by various scientists in the field of bioelectromagnetics and by the World Health Organization (WHO); however, these …

Neuromotor And Cognitive Development In Children With Cerebral Palsy In Relation To Neural Plasticity, Vaniecea Pollard

McCabe Thesis Collection

Infants with neurological disabilities, such as cerebral palsy (CP) and Down syndrome (DS), show severe delays in motor and cognitive development relative to chronological age. Involvement of neural plasticity as a treatment of such neurological disorders is increasingly being seen. Previous studies have found that interventions involving sensory linked motor performance have been critical in facilitating motor improvement. The purpose of this study was to compare self-initiated mobility in children with CP and DS. Three infants, ages 8, 9, and 22 months, with diagnoses of no CP, DS, and CP respectively, participated in the study. The infants were videotaped in …

An Analysis Of The Calcium And Iron Intake Of Langston University's Track And Basketball Athletes, Dominique Patrice Moore

McCabe Thesis Collection

Recommended Dietary Allowances (RDA's ) reflect that the average healthy American aged 18-24 years should consume 1,200 mg of calcium daily and 10-12 mg and 15 mg of iron for men and women respectively. These RDA's have not been adjusted for those persons involved in endurance sports. Studies by Telford (1992) and Clarkson (1992) show that endurance athletes suffer from calcium and iron deficiencies. There is a general assumption that athletic coaches are more concerned with the "weigh in" of 4 athletes than overall nutrient requirements. Positive nutrition education should be part of the overall training of athletes. Also, studies …

A Correlative Study Of An At-Risk Population And Low Birth Weight/Infant Mortality In A Northeast Oklahoma City Community, Estacia D. Thrower

McCabe Thesis Collection

Studies show that numerous and complex variables influence pregnancy outcomes and infant mortality rates. These variables include demographic, medical, physical, environmental, behavioral, and attitudinal factors and prenatal care. Improving the health of mothers and infants is a national challenge. In 1987, more than 3.8 million infants were born in the United States. Of these, 38,408 died before their first birthday. Although the infant mortality rate is at an all-time low, the pace of progress has slowed. According to Dr. Robert Deppen of the Oklahoma State Health Department, "In 1992, Oklahoma ranked 29th in the United States for infant mortality and …

Isolation From Soil Microorganisms That Are Inhibitory To Wheat Seeding Pathogens, Kynita Wilson-Humphrey

McCabe Thesis Collection

Many diseases caused by bacteria, viruses, or fungi are responsible for the ruin of a great number of crops annually. At present, many of these crops are being treated for diseases by synthetic or man-made chemicals. Some of the chemicals have been proved to have adverse effects on the environment, including humans and animals. Very few non-chemical means are available to farmers at this time to control these pathogens. This is due to the fact that many of the means of control have little effect against the pathogens or diseases. This research attempts to isolate microorganisms from the soil which …

Synthesis Of Nitrosyl Metallpoprphyrins, Thomas M. Braxton Jr.

McCabe Thesis Collection

Nitric oxide, NO, is a molecule with great versatility and importance. Made up of only a single atom of nitrogen and a single atom of oxygen, nitric oxide is perhaps one of the smallest paramagnetic molecules found in nature. The functions of NO in the body are not all known, but this molecule definitely plays a variety of roles. It is involved in the regulation of blood pressure, and it sometimes acts as a messenger for cells as well as a killer of them. It also is important in the defense of the body against foreign invaders. The significance of …

The Nutritional Knowledge, Food Choices, And Exercise Habits Of Students At Langston University, Preston Solomon

McCabe Thesis Collection

The nutritional knowledge, food choice, and exercise habits of an individual determine his or her overall health and life expectancy. Information on these topics enables nutrition educators to develop strategies to improve knowledge and to tailor educational efforts which affect a large number of persons. Poor health in America today is an ever present reality. Heart disease, cancer, diabetes mellitus, cerebrovascular diseases, renal diseases, and pulmonary diseases are causes of death related in part to lack of nutritional knowledge and poor eating and exercise habits. A few of these diseases are chronic in nature and are the most deadly.

The …

The General Adaptation Syndrome In Gerbillus, Bridget L. Moore

McCabe Thesis Collection

The General Adaptation Syndrome or the G.A.S. is the term applied to collective responses to physiological stress. It is initiated by any disturbance in the normal balance of the body functions. These responses affect humans, monkeys, and other animals. The three main physiological changes which occur as a result of stress are enlarged adrenals, shrunken lymphatic organs, and bleeding gastrointestinal ulcers. There are also concomitant changes in the hematocrit and the formed elements of blood. In particular, there is usually a decrease in lymphocytes and eosinophils accompanied by the increase in neutrophils and platelets.

Stress is defined as pressure, or …

How Amaranth Grain Affects Total Body Weight And Major Organ Weight In The Mongolian Gerbil, Rhoshonda Montgomery- Conway

McCabe Thesis Collection

Purpose and Objectives

The purpose of this research is to determine effects of amaranth grain of the body weight and organ weight of the Mongolian gerbil. The literature research indicates that amaranth results in physiological changes that appear to be species-specific rather than general. Since the gerbil is a granivorous animal, it is hypothesized that amaranth will be completely digested and that its nutritional quality will maintain normal to increased growth. While the results of this study cannot be applied to other animals, information has been gained with regard to the influence of amaranth grain on the Mongolian gerbil.

An Analysis Of The Potability Of Water In Logan County, Oscar D. James

McCabe Thesis Collection

Recent questions have been raised concerning the drinking water supplying the citizens of Logan County. This study seeks to determine how well Logan County's potable water supply conforms with state and national drinking water standards. Emphasis is placed on the maximum contaminant levels of water supplying the Langston community and surrounding areas. Questions posed to

A Survey Of Helminths Of Ondatra Zibethicus In Eight States And Four Foreign Countries, Mike P. Lyons

McCabe Thesis Collection

The muskrat, Ondatra zibethicus. is a large member of the Order Rodentia and regarded as the United States' most important fur bearing mammal (Abram, 19 69) . Helminths, or parasitic worms, include amongst its members: trematodes (flukes), cestodes (tape worms) and nematodes (round worms). Parasite surveys based on geography and subspecies of the host, Ondatra zibethicus. have pieced together information gaps based on these criteria and enabled investigators to construct an overall picture of helminth parasites in the United States and elsewhere.

The question of helminths in representative host species can be addressed either through necropsy examinations or through literature …