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Health Effects Of Dietary Fermentable Fiber (Resistant Starch), Diana Gabriela Carvajal-Aldaz

LSU Doctoral Dissertations

Resistant starch (RS) reaches the large intestine for fermentation and is considered a prebiotic. We wanted to determine if we could reduce fermentation for future mechanistic studies and how there is improved insulin sensitivity in human studies with or without increased incretin hormone glucagon-like peptide 1 (GLP-1). Two main studies were performed. In the first main study, low potency antibiotics (Ampicillin 1g/L and Neomycin 0.5g/L) were added to the drinking water of rats to reduce fermentation of RS. Antibiotics were used either prior (first) to or during (second) feeding of RS. Results demonstrated that low potency antibiotics given prior to …