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Effect Of Voluntary Exercise And Diet On The Unfolded Protein Response In The Brain Of Mice, Yu Ho Kim
Effect Of Voluntary Exercise And Diet On The Unfolded Protein Response In The Brain Of Mice, Yu Ho Kim
All Graduate Theses and Dissertations, Spring 1920 to Summer 2023
The medical costs for many chronic diseases are increasing dramatically and placing a major financial burden on nations and individuals in both developed and developing countries. A number of chronic diseases, such as obesity, type 2 diabetes and some neurodegenerative diseases are all attenuated by a history of physical activity suggesting that they may be interconnected in some way. It has been suggested that cellular stress is a major factor promoting these chronic diseases.
Cellular stress occurs in a specific compartment within the cell, the endoplasmic reticulum, whose normal function is in the synthesis and folding of proteins into the …