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Loss Of Tsc2 Results In Abnormal Postnatal Neurogenesis And Striatal Hamartomas, Victoria Riley May 2024

Loss Of Tsc2 Results In Abnormal Postnatal Neurogenesis And Striatal Hamartomas, Victoria Riley

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Billions of years of evolution have culminated in the most complex organ in all of biology: the brain. Its capacity to sense, store, and predict information uniquely bestows humans with the capability to generate art, music, language, and math and sets humans apart from other species. It is therefore prudent and worthwhile to study the brain and its development. A critical aspect of brain development is neurogenesis, or the production of neurons. Neurogenesis is facilitated by neural stem cells (NSCs) and is influenced by the mTORC1 signaling pathway. For NSCs to differentiate and become committed to a neuronal cell fate, …