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Neural Preparation For Step Initiation In Unpredictable Conditions With Age And Parkinson's Disease, Roman Popov
Neural Preparation For Step Initiation In Unpredictable Conditions With Age And Parkinson's Disease, Roman Popov
Graduate College Dissertations and Theses
Mobility is essential for the independent lifestyle. However, as the US population ages, challenges to mobility start to arise, among them just the aging itself which leads to decreased postural stability, falls and the second most common neurodegenerative disease, that is Parkinson’s disease (PD). We decided to investigate step initiation as it is crucial to mobility: walking is not possible without the first step.
Step initiation is impaired in PD. However, the impact of PD on the neural mechanisms of step initiation when some of the step parameters are unpredictable remains unexplored. Cortical preparation for step initiation can be assessed …